Hesperidin (HD), a citrus bioflavonoid possesses quite a lot of organic actions together with antioxidant, anti-inflammatory, anti-apoptotic and anti-carcinogenic properties. Within the current examine, we investigated the impact of HD remedy on N,N’-dimethylhydrazine (DMH) induced oxidative stress, irritation, apoptosis and goblet cell disintegration within the colon of Wistar rats. Administration of HD was accomplished at two doses (100 and 200 mg/kg physique weight) orally to rats each day for <em>14</em> days adopted by a single subcutaneous injection of DMH (40 mg/kg physique weight) on the <em>14</em>th day and subsequent day animals had been sacrificed.
The protecting potential of HD towards colon toxicity was measured by membrane oxidation, antioxidant standing, inflammatory and apoptotic markers expression, and histological adjustments. Outcomes demonstrated that HD inhibited DMH mediated oxidative harm by diminishing the extent of peroxidation of lipids and rising the exercise of superoxide dismutase, catalase, diminished glutathione, glutathione peroxidase, glutathione-s-transferase, and glutathione reductase. Furthermore, HD attenuated inflammatory (NF-кB, IL-6, and COX-2) and apoptotic (p38-MAPK, p53, and <em>caspase</em>-3) markers expression.
HD additionally attenuated the DMH induced goblet cell disintegration and restored histoarchitecture of the colon. The outcomes of the current examine exhibit that HD effectively protects towards DMH induced colon toxicity by modulating oxidative stress, irritation, and apoptosis.
Molecular subtype-specific responses of colon most cancers cells to the SMAC mimetic Birinapant
Colorectal most cancers is a molecularly heterogeneous illness. Responses to genotoxic chemotherapy within the adjuvant or palliative setting differ drastically between sufferers, and colorectal most cancers cells typically resist chemotherapy by evading apoptosis. Antagonists of an inhibitor of apoptosis proteins (IAPs) can restore faulty apoptosis signaling by degrading cIAP1 and cIAP2 proteins and by inhibition of XIAP. Because of the a number of molecular mechanisms-of-action of those targets, responses to IAP antagonist could differ between molecularly distinct colon most cancers cells. On this examine, responses to the IAP antagonist Birinapant and oxaliplatin/5-fluorouracil (5-FU) had been investigated in <em>14</em> colon most cancers cell strains, representing the consensus molecular subtypes (CMS). Therapy with Birinapant alone didn’t lead to a considerable enhance in apoptotic cells on this cell line panel.
Annexin-V/PI assays quantified by circulate cytometry and high-content screening confirmed that Birinapant elevated responses of CMS1 and partially CMS3 cell strains to oxaliplatin/5-FU, whereas CMS2 cells weren’t successfully sensitized. FRET-based imaging of <em>caspase</em>-Eight and -Three activation validated these variations on the single-cell degree, with CMS1 cells displaying sustained activation of <em>caspase</em>-8-like exercise throughout Birinapant and oxaliplatin/5-FU co-treatment, in the end activating the intrinsic mitochondrial apoptosis pathway. In CMS2 cell strains, Birinapant exhibited synergistic results together with TNFα, suggesting that Birinapant can restore extrinsic apoptosis signaling within the context of inflammatory indicators on this subtype. To discover this additional, we co-cultured CMS2 and CMS1 colon most cancers cells with peripheral blood mononuclear cells. We noticed elevated cell loss of life throughout Birinapant single remedy in these co-cultures, which was abrogated by anti-TNFα-neutralizing antibodies.
Collectively, our examine demonstrates that IAP inhibition is a promising modulator of response to oxaliplatin/5-FU in
colorectal cancers of the CMS1 subtype, and will present promise as within the CMS2 subtype, suggesting that molecular subtyping could assist as a affected person stratification software for IAP antagonists on this illness.
Protective effect of hesperidin against N,N’-dimethylhydrazine induced oxidative stress, inflammation, and apoptotic response in the colon of Wistar rats
The impact of calcium phosphate biodegradable coatings of titanium implants on cell differentiation and apoptosis in rat bone tissue after experimental fracture
Background: The effectiveness of bone restore is set by the stability of proliferative and harmful elements within the fracture union web site. It may be enhanced through the use of varied nanostructured supplies possessing osteoinductive properties, particularly titanium implants with biodegradable calcium phosphate coatings. The consequences of those coatings on the state of stem cells, their differentiation and distribution within the restore zone is unknown.
Goal: To check the dynamics of proliferation, differentiation, and apoptosis of stem cells after experimental fracture adopted by implantation of titanium implants with calcium phosphate coatings
The localization of proliferation (PCNA) and differentiation (CD44 and osteocalcin) elements and apoptotic molecules (MDM2, p53, <em>caspase</em>-3) was studied in a rat femoral fracture mannequin with implant placement. Titanium implant screws with bioactive calcium phosphate and hydroxyapatite coatings fashioned by plasma electrolytic oxidation had been used within the examine. Experimental rats had been organized into three teams (15 animals per group): management group; rats implanted with uncoated implants; and rats implanted with coated implants. Management rats had been topic to the same fracture as experimental ones and had been allowed to heal conservatively. Rats from all teams had been sampled on days 7, <em>14</em>, and 30 after harm.
Low-differentiated PCNA-, osteocalcin-, and CD44-immunopositive cells had been localized across the implant within the internal layer of the periosteum, layer of outer circumferential lamellae, and connective tissue lining of haversian canals. The spatial density of cells expressing the above proliferation and differentiation elements, in addition to that of MDM2-immunoreactive cells, elevated on day 7 and decreased by day 30 after harm. The spatial density of apoptotic cells reached the utmost on day <em>14</em> after harm. They had been primarily discovered within the internal layer of the periosteum and outer circumferential lamellae. p53- and <em>caspase</em>-3-positive cells occurred on the floor of the concentric lamellae surrounding haversian canals and below the periosteum. Their spatial density decreased by day 30 after harm.
 Caspase-12 Blocking Peptide |
|
3282BP-50 |
Biovision |
|
EUR 153 |
 Caspase 12 Blocking Peptide |
|
20-abx064041 |
Abbexa |
|
|
|
|
 Antibody) Caspase 12 (Caspase 12) Antibody |
|
20-abx007974 |
Abbexa |
-
EUR 300.00
-
EUR 439.00
-
EUR 189.00
|
|
|
|
Caspase 12 (Caspase 12) Antibody |
|
abx432451-200ul |
Abbexa |
200 ul |
EUR 384 |
|
|
Caspase 12 (Caspase 12) Antibody |
|
abx231286-100ug |
Abbexa |
100 ug |
EUR 481 |
|
|
 Human cysteinyl aspartate specific proteinases 12,Caspase-12 ELISA Kit |
|
201-12-0763 |
SunredBio |
96 tests |
EUR 440 |
|
|
|
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
 Caspase 12 antibody |
|
70R-51166 |
Fitzgerald |
100 ul |
EUR 244 |
|
Description: Purified Polyclonal Caspase 12 antibody |
Caspase 12 antibody |
|
20R-1513 |
Fitzgerald |
100 ug |
EUR 673 |
|
Description: Rabbit polyclonal Caspase 12 antibody |
Caspase 12 antibody |
|
70R-11740 |
Fitzgerald |
100 ug |
EUR 460 |
|
Description: Rabbit polyclonal Caspase 12 antibody |
 Caspase-12 Antibody |
|
3282-100 |
Biovision |
|
EUR 354 |
Caspase-12 Antibody |
|
3282-30T |
Biovision |
|
EUR 146 |
Caspase-12 Antibody |
|
24119-100ul |
SAB |
100ul |
EUR 390 |
Caspase-12 Antibody |
|
24120-100ul |
SAB |
100ul |
EUR 390 |
 Caspase 12 Assay Kit |
|
55R-1290 |
Fitzgerald |
25 assays |
EUR 328 |
|
Description: Assay Kit for detection of Capase 12 activity in the research laboratory |
) Recombinant Caspase 12 (CASP12) |
|
4-RPA682Mu01 |
Cloud-Clone |
-
EUR 467.36
-
EUR 228.00
-
EUR 1477.60
-
EUR 559.20
-
EUR 1018.40
-
EUR 376.00
-
EUR 3544.00
|
-
100 ug
-
10ug
-
1 mg
-
200 ug
-
500 ug
-
50ug
-
5 mg
|
|
|
|
Description: Recombinant Mouse Caspase 12 expressed in: E.coli |
Recombinant Caspase 12 (CASP12) |
|
4-RPA682Ra01 |
Cloud-Clone |
-
EUR 494.24
-
EUR 235.00
-
EUR 1578.40
-
EUR 592.80
-
EUR 1085.60
-
EUR 394.00
-
EUR 3796.00
|
-
100 ug
-
10ug
-
1 mg
-
200 ug
-
500 ug
-
50ug
-
5 mg
|
|
|
|
Description: Recombinant Rat Caspase 12 expressed in: E.coli |
 Antibody) Caspase 12 (CASP12) Antibody |
|
20-abx129818 |
Abbexa |
-
EUR 411.00
-
EUR 133.00
-
EUR 1135.00
-
EUR 551.00
-
EUR 314.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
|
Caspase 12 (CASP12) Antibody |
|
20-abx111421 |
Abbexa |
|
|
|
|
Caspase 12 (CASP12) Antibody |
|
20-abx100899 |
Abbexa |
-
EUR 425.00
-
EUR 133.00
-
EUR 1177.00
-
EUR 578.00
-
EUR 328.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
|
 Caspase-12 Rabbit pAb |
|
A0217-100ul |
Abclonal |
100 ul |
EUR 308 |
Caspase-12 Rabbit pAb |
|
A0217-200ul |
Abclonal |
200 ul |
EUR 459 |
Caspase-12 Rabbit pAb |
|
A0217-20ul |
Abclonal |
20 ul |
EUR 183 |
Caspase-12 Rabbit pAb |
|
A0217-50ul |
Abclonal |
50 ul |
EUR 223 |
 Caspase 12 Polyclonal Antibody |
|
ABP50853-003ml |
Abbkine |
0.03ml |
EUR 158 |
|
|
|
Description: A polyclonal antibody for detection of Caspase 12 from Human. This Caspase 12 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Caspase12 |
Caspase 12 Polyclonal Antibody |
|
ABP50853-01ml |
Abbkine |
0.1ml |
EUR 289 |
|
|
|
Description: A polyclonal antibody for detection of Caspase 12 from Human. This Caspase 12 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Caspase12 |
Caspase 12 Polyclonal Antibody |
|
ABP50853-02ml |
Abbkine |
0.2ml |
EUR 414 |
|
|
|
Description: A polyclonal antibody for detection of Caspase 12 from Human. This Caspase 12 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Caspase12 |
Caspase 12 (CASP12) Antibody |
|
abx026563-400ul |
Abbexa |
400 ul |
EUR 523 |
|
|
Caspase 12 (CASP12) Antibody |
|
abx026563-80l |
Abbexa |
80 µl |
EUR 286 |
|
|
 Anti-Caspase-12 Antibody |
|
A04700 |
BosterBio |
100ug |
EUR 471 |
|
Description: Rabbit Polyclonal Caspase-12 Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat. |
Caspase 12 (CASP12) Antibody |
|
20-abx318255 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
-
100 ug
-
1 mg
-
200 ug
-
20 ug
-
50 ug
|
|
|
 Antibody) Caspase 12 (Casp12) Antibody |
|
20-abx318989 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
-
100 ug
-
1 mg
-
200 ug
-
20 ug
-
50 ug
|
|
|
Caspase 12 (CASP12) Antibody |
|
abx216233-100ug |
Abbexa |
100 ug |
EUR 439 |
|
|
Caspase 12 (CASP12) Antibody |
|
20-abx213378 |
Abbexa |
|
|
|
|
Caspase 12 (CASP12) Antibody |
|
20-abx210324 |
Abbexa |
|
|
|
|
 Polyclonal Caspase-12 Antibody |
|
APR06275G |
Leading Biology |
0.1 mg |
EUR 659 |
|
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-12 . This antibody is tested and proven to work in the following applications: |
Polyclonal Caspase-12 Antibody |
|
APR06276G |
Leading Biology |
0.1 mg |
EUR 659 |
|
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-12 . This antibody is tested and proven to work in the following applications: |
) Caspase-12 Antibody (Large) |
|
24208-100ul |
SAB |
100ul |
EUR 390 |
) Caspase-12 Antibody (Small) |
|
24209-100ul |
SAB |
100ul |
EUR 390 |
Caspase 12 (CASP12) Antibody |
|
20-abx324638 |
Abbexa |
|
|
|
|
Polyclonal Caspase-12 Antibody |
|
APR00058G |
Leading Biology |
0.1mg |
EUR 484 |
|
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-12 . This antibody is tested and proven to work in the following applications: |
 anti- Caspase 12 antibody |
|
FNab01286 |
FN Test |
100µg |
EUR 505.25 |
|
|
|
Description: Antibody raised against Caspase 12 |
 99445-12 DCT 12 X 75MM |
|
99445-12 |
CORNING |
250/pk |
EUR 67 |
|
Description: Disposable Culture Tubes; DCT's, CGW |
 Human Caspase 12,Casp-12 ELISA Kit |
|
CN-03708H1 |
ChemNorm |
96T |
EUR 486 |
Human Caspase 12,Casp-12 ELISA Kit |
|
CN-03708H2 |
ChemNorm |
48T |
EUR 336 |
 Human Caspase 12 ELISA kit |
|
E01C0690-192T |
BlueGene |
192 tests |
EUR 1270 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Human Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Caspase 12 ELISA kit |
|
E01C0690-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Human Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Caspase 12 ELISA kit |
|
E01C0690-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Human Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Mouse Caspase 12 ELISA kit |
|
E03C0690-192T |
BlueGene |
192 tests |
EUR 1270 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Mouse Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Caspase 12 ELISA kit |
|
E03C0690-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Mouse Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Caspase 12 ELISA kit |
|
E03C0690-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Mouse Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Rabbit Caspase 12 ELISA kit |
|
E04C0690-192T |
BlueGene |
192 tests |
EUR 1270 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Rabbit Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Caspase 12 ELISA kit |
|
E04C0690-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Rabbit Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Caspase 12 ELISA kit |
|
E04C0690-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Rabbit Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Rat Caspase 12 ELISA kit |
|
E02C0690-192T |
BlueGene |
192 tests |
EUR 1270 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Rat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Caspase 12 ELISA kit |
|
E02C0690-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Rat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Caspase 12 ELISA kit |
|
E02C0690-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Rat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Caspase-12 Substrate ATAD-AFC |
|
1117-1000 |
Biovision |
|
EUR 1088 |
Caspase-12 Substrate ATAD-AFC |
|
1117-200 |
Biovision |
|
EUR 436 |
 Pig Caspase 12 ELISA kit |
|
E07C0690-192T |
BlueGene |
192 tests |
EUR 1270 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Porcine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Caspase 12 ELISA kit |
|
E07C0690-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Porcine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Caspase 12 ELISA kit |
|
E07C0690-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Porcine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Dog Caspase 12 ELISA kit |
|
E08C0690-192T |
BlueGene |
192 tests |
EUR 1270 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Canine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Caspase 12 ELISA kit |
|
E08C0690-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Canine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Caspase 12 ELISA kit |
|
E08C0690-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Canine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Goat Caspase 12 ELISA kit |
|
E06C0690-192T |
BlueGene |
192 tests |
EUR 1270 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Goat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Caspase 12 ELISA kit |
|
E06C0690-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Goat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Caspase 12 ELISA kit |
|
E06C0690-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Goat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Caspase-12 Fluorometric Assay Kit |
|
K139-100 |
Biovision |
|
EUR 501 |
Caspase-12 Fluorometric Assay Kit |
|
K139-25 |
Biovision |
|
EUR 256 |
 Monkey Caspase 12 ELISA kit |
|
E09C0690-192T |
BlueGene |
192 tests |
EUR 1270 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Monkey Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Caspase 12 ELISA kit |
|
E09C0690-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Monkey Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Caspase 12 ELISA kit |
|
E09C0690-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Monkey Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 Mouse Caspase-12 ELISA Kit |
|
EMC0697 |
Abclonal |
96Tests |
EUR 521 |
 Porcine Caspase-12 ELISA Kit |
|
EPC0697 |
Abclonal |
96Tests |
EUR 521 |
 Rat Caspase-12 ELISA Kit |
|
ERC0697 |
Abclonal |
96Tests |
EUR 521 |
 Rabbit Caspase-12 ELISA Kit |
|
ERTC0697 |
Abclonal |
96Tests |
EUR 521 |
 Anti-Caspase-12/CASP12 Antibody |
|
PA2103 |
BosterBio |
100ug/vial |
EUR 334 |
 Anserini Caspase-12 ELISA Kit |
|
EAC0697 |
Abclonal |
96Tests |
EUR 521 |
 Goat Caspase-12 ELISA Kit |
|
EGTC0697 |
Abclonal |
96Tests |
EUR 521 |
 Canine Caspase-12 ELISA Kit |
|
ECC0697 |
Abclonal |
96Tests |
EUR 521 |
 Human Caspase-12 ELISA Kit |
|
EHC0697 |
Abclonal |
96Tests |
EUR 521 |
 Bovine Caspase-12 ELISA Kit |
|
EBC0697 |
Abclonal |
96Tests |
EUR 521 |
 Protein) Rat Caspase 12 (CASP12) Protein |
|
20-abx065753 |
Abbexa |
-
EUR 690.00
-
EUR 286.00
-
EUR 2124.00
-
EUR 815.00
-
EUR 495.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
|
 Antibody (HRP)) Caspase 12 (Casp12) Antibody (HRP) |
|
20-abx318990 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
-
100 ug
-
1 mg
-
200 ug
-
20 ug
-
50 ug
|
|
|
 Antibody (FITC)) Caspase 12 (Casp12) Antibody (FITC) |
|
20-abx318991 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
-
100 ug
-
1 mg
-
200 ug
-
20 ug
-
50 ug
|
|
|
 Antibody (Biotin)) Caspase 12 (Casp12) Antibody (Biotin) |
|
20-abx318992 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
-
100 ug
-
1 mg
-
200 ug
-
20 ug
-
50 ug
|
|
|
 Antibody (HRP)) Caspase 12 (CASP12) Antibody (HRP) |
|
20-abx316303 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
-
100 ug
-
1 mg
-
200 ug
-
20 ug
-
50 ug
|
|
|
 Antibody (FITC)) Caspase 12 (CASP12) Antibody (FITC) |
|
20-abx316304 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
-
100 ug
-
1 mg
-
200 ug
-
20 ug
-
50 ug
|
|
|
 Antibody (Biotin)) Caspase 12 (CASP12) Antibody (Biotin) |
|
20-abx316305 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
-
100 ug
-
1 mg
-
200 ug
-
20 ug
-
50 ug
|
|
|
 Protein) Mouse Caspase 12 (CASP12) Protein |
|
20-abx167225 |
Abbexa |
-
EUR 648.00
-
EUR 272.00
-
EUR 1998.00
-
EUR 773.00
-
EUR 467.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
|
) Polyclonal Caspase-12 Antibody (Large) |
|
APR06327G |
Leading Biology |
0.1 mg |
EUR 659 |
|
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-12 (Large). This antibody is tested and proven to work in the following applications: |
) Polyclonal Caspase-12 Antibody (Small) |
|
APR06328G |
Leading Biology |
0.1 mg |
EUR 659 |
|
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-12 (Small). This antibody is tested and proven to work in the following applications: |
Caspase-12 Fluorometric Assay Kit |
|
K2150-100 |
ApexBio |
100 assays |
EUR 529 |
Caspase-12 Fluorometric Assay Kit |
|
K2150-25 |
ApexBio |
25 assays |
EUR 251 |
 Apelin-12 Peptide |
|
20-abx266317 |
Abbexa |
-
EUR 495.00
-
EUR 815.00
-
EUR 356.00
|
|
|
|
 Individual Reaction Mix 12 |
|
G065-12 |
ABM |
200 reactions |
EUR 167 |
 Human 12-lipoxygenase,LOX-12 ELISA Kit |
|
201-12-0949 |
SunredBio |
96 tests |
EUR 440 |
|
|
|
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
 Tissue Culture Plate, 12 Well |
|
TCP20-12 |
Bio Basic |
1 UNIT |
EUR 53.48 |
|
|
 Human Interleukin 12,IL-12/P70 ELISA KIT |
|
201-12-0100 |
SunredBio |
96 tests |
EUR 440 |
|
|
|
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
 Human Interleukin 12,IL-12/P40 ELISA KIT |
|
201-12-0101 |
SunredBio |
96 tests |
EUR 440 |
|
|
|
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
 Caspase-12 Inhibitor Z-ATAD-FMK |
|
1079-100 |
Biovision |
|
EUR 218 |
Caspase-12 Inhibitor Z-ATAD-FMK |
|
1079-20C |
Biovision |
|
EUR 218 |
 CaspGLOW Active Caspase 12 Staining Kit |
|
55R-1291 |
Fitzgerald |
25 assays |
EUR 282 |
|
Description: Caspase 12 Staining Kit for use activity in the research laboratory |
 ELISA Kit) Mouse Caspase 12 (CASP12) ELISA Kit |
|
SEA682Mu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 4862.4 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Caspase 12 (CASP12) in tissue homogenates, cell lysates and other biological fluids. |
Mouse Caspase 12 (CASP12) ELISA Kit |
|
SEA682Mu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 488.08 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Caspase 12 (CASP12) in tissue homogenates, cell lysates and other biological fluids. |
Mouse Caspase 12 (CASP12) ELISA Kit |
|
SEA682Mu-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 654.4 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Caspase 12 (CASP12) in tissue homogenates, cell lysates and other biological fluids. |
Mouse Caspase 12 (CASP12) ELISA Kit |
|
SEA682Mu-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 2644.8 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Caspase 12 (CASP12) in tissue homogenates, cell lysates and other biological fluids. |
Mouse Caspase 12 (CASP12) ELISA Kit |
|
4-SEA682Mu |
Cloud-Clone |
-
EUR 4913.00
-
EUR 2595.00
-
EUR 655.00
|
-
10 plates of 96 wells
-
5 plates of 96 wells
-
1 plate of 96 wells
|
|
|
|
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Caspase 12 (CASP12) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
 Polyclonal Antibody (Mouse)) Caspase 12 (CASP12) Polyclonal Antibody (Mouse) |
|
4-PAA682Mu01 |
Cloud-Clone |
-
EUR 236.00
-
EUR 2338.00
-
EUR 586.00
-
EUR 294.00
-
EUR 209.00
|
-
100ul
-
10ml
-
1ml
-
200ul
-
20ul
|
|
|
|
Description: A Rabbit polyclonal antibody against Mouse Caspase 12 (CASP12) |
 Guinea pig Caspase 12 ELISA kit |
|
E05C0690-192T |
BlueGene |
192 tests |
EUR 1270 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Guinea pig Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Guinea pig Caspase 12 ELISA kit |
|
E05C0690-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Guinea pig Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Guinea pig Caspase 12 ELISA kit |
|
E05C0690-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
|
|
Description: A competitive ELISA for quantitative measurement of Guinea pig Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
 ELISA Kit) Human Caspase 12 (CASP12) ELISA Kit |
|
abx513694-96tests |
Abbexa |
96 tests |
EUR 707 |
|
|
ELISA kit) Mouse Caspase 12(CASP13)ELISA kit |
|
GA-E0794MS-48T |
GenAsia Biotech |
48T |
EUR 336 |
Mouse Caspase 12(CASP13)ELISA kit |
|
GA-E0794MS-96T |
GenAsia Biotech |
96T |
EUR 534 |
 Rat Casp12/ Caspase-12 ELISA Kit |
|
E0156Ra |
Sunlong |
1 Kit |
EUR 571 |
 Mouse Casp12/ Caspase-12 ELISA Kit |
|
E0211Mo |
Sunlong |
1 Kit |
EUR 571 |
 Guinea Pig Caspase-12 ELISA Kit |
|
EGC0697 |
Abclonal |
96Tests |
EUR 521 |
 CLIA Kit) Mouse Caspase 12 (CASP12) CLIA Kit |
|
20-abx491877 |
Abbexa |
-
EUR 7973.00
-
EUR 4246.00
-
EUR 981.00
|
-
10 × 96 tests
-
5 × 96 tests
-
96 tests
|
|
|
 ELISA Kit) Rat Caspase 12 (CASP12) ELISA Kit |
|
abx256323-96tests |
Abbexa |
96 tests |
EUR 786 |
|
|
Mouse Caspase 12 (CASP12) ELISA Kit |
|
20-abx258452 |
Abbexa |
-
EUR 7378.00
-
EUR 3933.00
-
EUR 911.00
|
-
10 × 96 tests
-
5 × 96 tests
-
96 tests
|
|
|
Human Caspase 12 (CASP12) ELISA Kit |
|
20-abx259273 |
Abbexa |
-
EUR 6642.00
-
EUR 3542.00
-
EUR 825.00
|
-
10 × 96 tests
-
5 × 96 tests
-
96 tests
|
|
|
Mouse Caspase 12 (CASP12) ELISA Kit |
|
abx254790-96tests |
Abbexa |
96 tests |
EUR 668 |
|
|
Rat Caspase 12 (CASP12) ELISA Kit |
|
abx353550-96tests |
Abbexa |
96 tests |
EUR 786 |
|
|
Human Caspase 12 (CASP12) ELISA Kit |
|
abx358592-96tests |
Abbexa |
96 tests |
EUR 707 |
|
|
 CLIA Kit) Human Caspase 12 (CASP12) CLIA Kit |
|
abx196504-96tests |
Abbexa |
96 tests |
EUR 825 |
|
|
Conclusions: Calcium phosphate coatings stimulate cell proliferation at early levels of fracture restoration and apoptotic cell loss of life at later levels. Coating parts could present positional data guiding the differentiation of mesenchymal stromal cells. A change within the exercise of apoptotic elements, osteocalcin, and CD44 is brought on by gene induction in response to the diffusion of calcium phosphate compounds from coating to surrounding tissue.
)
