Protective effect of hesperidin against N,N'-dimethylhydrazine induced oxidative stress, inflammation, and apoptotic response in the colon of Wistar rats
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December 11, 2020

Protective effect of hesperidin against N,N’-dimethylhydrazine induced oxidative stress, inflammation, and apoptotic response in the colon of Wistar rats

By Dylan

Hesperidin (HD), a citrus bioflavonoid possesses quite a lot of organic actions together with antioxidant, anti-inflammatory, anti-apoptotic and anti-carcinogenic properties. Within the current examine, we investigated the impact of HD remedy on N,N’-dimethylhydrazine (DMH) induced oxidative stress, irritation, apoptosis and goblet cell disintegration within the colon of Wistar rats. Administration of HD was accomplished at two doses (100 and 200 mg/kg physique weight) orally to rats each day for <em>14</em> days adopted by a single subcutaneous injection of DMH (40 mg/kg physique weight) on the <em>14</em>th day and subsequent day animals had been sacrificed.

The protecting potential of HD towards colon toxicity was measured by membrane oxidation, antioxidant standing, inflammatory and apoptotic markers expression, and histological adjustments. Outcomes demonstrated that HD inhibited DMH mediated oxidative harm by diminishing the extent of peroxidation of lipids and rising the exercise of superoxide dismutase, catalase, diminished glutathione, glutathione peroxidase, glutathione-s-transferase, and glutathione reductase. Furthermore, HD attenuated inflammatory (NF-кB, IL-6, and COX-2) and apoptotic (p38-MAPK, p53, and <em>caspase</em>-3) markers expression.

HD additionally attenuated the DMH induced goblet cell disintegration and restored histoarchitecture of the colon. The outcomes of the current examine exhibit that HD effectively protects towards DMH induced colon toxicity by modulating oxidative stress, irritation, and apoptosis.

 

Molecular subtype-specific responses of colon most cancers cells to the SMAC mimetic Birinapant

Colorectal most cancers is a molecularly heterogeneous illness. Responses to genotoxic chemotherapy within the adjuvant or palliative setting differ drastically between sufferers, and colorectal most cancers cells typically resist chemotherapy by evading apoptosis. Antagonists of an inhibitor of apoptosis proteins (IAPs) can restore faulty apoptosis signaling by degrading cIAP1 and cIAP2 proteins and by inhibition of XIAP. Because of the a number of molecular mechanisms-of-action of those targets, responses to IAP antagonist could differ between molecularly distinct colon most cancers cells. On this examine, responses to the IAP antagonist Birinapant and oxaliplatin/5-fluorouracil (5-FU) had been investigated in <em>14</em> colon most cancers cell strains, representing the consensus molecular subtypes (CMS). Therapy with Birinapant alone didn’t lead to a considerable enhance in apoptotic cells on this cell line panel.
Annexin-V/PI assays quantified by circulate cytometry and high-content screening confirmed that Birinapant elevated responses of CMS1 and partially CMS3 cell strains to oxaliplatin/5-FU, whereas CMS2 cells weren’t successfully sensitized. FRET-based imaging of <em>caspase</em>-Eight and -Three activation validated these variations on the single-cell degree, with CMS1 cells displaying sustained activation of <em>caspase</em>-8-like exercise throughout Birinapant and oxaliplatin/5-FU co-treatment, in the end activating the intrinsic mitochondrial apoptosis pathway. In CMS2 cell strains, Birinapant exhibited synergistic results together with TNFα, suggesting that Birinapant can restore extrinsic apoptosis signaling within the context of inflammatory indicators on this subtype. To discover this additional, we co-cultured CMS2 and CMS1 colon most cancers cells with peripheral blood mononuclear cells. We noticed elevated cell loss of life throughout Birinapant single remedy in these co-cultures, which was abrogated by anti-TNFα-neutralizing antibodies.
Collectively, our examine demonstrates that IAP inhibition is a promising modulator of response to oxaliplatin/5-FU in colorectal cancers of the CMS1 subtype, and will present promise as within the CMS2 subtype, suggesting that molecular subtyping could assist as a affected person stratification software for IAP antagonists on this illness.

Protective effect of hesperidin against N,N'-dimethylhydrazine induced oxidative stress, inflammation, and apoptotic response in the colon of Wistar rats

Protective effect of hesperidin against N,N’-dimethylhydrazine induced oxidative stress, inflammation, and apoptotic response in the colon of Wistar rats

The impact of calcium phosphate biodegradable coatings of titanium implants on cell differentiation and apoptosis in rat bone tissue after experimental fracture

Background: The effectiveness of bone restore is set by the stability of proliferative and harmful elements within the fracture union web site. It may be enhanced through the use of varied nanostructured supplies possessing osteoinductive properties, particularly titanium implants with biodegradable calcium phosphate coatings. The consequences of those coatings on the state of stem cells, their differentiation and distribution within the restore zone is unknown.
Goal: To check the dynamics of proliferation, differentiation, and apoptosis of stem cells after experimental fracture adopted by implantation of titanium implants with calcium phosphate coatings
The localization of proliferation (PCNA) and differentiation (CD44 and osteocalcin) elements and apoptotic molecules (MDM2, p53, <em>caspase</em>-3) was studied in a rat femoral fracture mannequin with implant placement. Titanium implant screws with bioactive calcium phosphate and hydroxyapatite coatings fashioned by plasma electrolytic oxidation had been used within the examine. Experimental rats had been organized into three teams (15 animals per group): management group; rats implanted with uncoated implants; and rats implanted with coated implants. Management rats had been topic to the same fracture as experimental ones and had been allowed to heal conservatively. Rats from all teams had been sampled on days 7, <em>14</em>, and 30 after harm.
 Low-differentiated PCNA-, osteocalcin-, and CD44-immunopositive cells had been localized across the implant within the internal layer of the periosteum, layer of outer circumferential lamellae, and connective tissue lining of haversian canals. The spatial density of cells expressing the above proliferation and differentiation elements, in addition to that of MDM2-immunoreactive cells, elevated on day 7 and decreased by day 30 after harm. The spatial density of apoptotic cells reached the utmost on day <em>14</em> after harm. They had been primarily discovered within the internal layer of the periosteum and outer circumferential lamellae. p53- and <em>caspase</em>-3-positive cells occurred on the floor of the concentric lamellae surrounding haversian canals and below the periosteum. Their spatial density decreased by day 30 after harm.

Caspase 12 Blocking Peptide
20-abx064041
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg

Caspase-12 Peptide (Large)
3195P 0.05 mg
EUR 164.75
Description: Caspase-12 peptide (Large)

Caspase-12 Peptide (Small)
3197P 0.05 mg
EUR 164.75
Description: Caspase-12 peptide (Small)

Caspase 12 Blocking Peptide
33R-10465 50 ug
EUR 349
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of Caspase 12 antibody, catalog no. 20R-1513

Caspase 12 Blocking Peptide
33R-10701 50 ug
EUR 191
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of Caspase 12 antibody, catalog no. 70R-11740

Caspase-12 Blocking Peptide
3282BP-50
EUR 153

Caspase 12 (Caspase 12) Antibody
20-abx007974
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

Caspase 12 (Caspase 12) Antibody
abx432451-200ul 200 ul
EUR 384

Caspase 12 (Caspase 12) Antibody
abx231286-100ug 100 ug
EUR 481

Human cysteinyl aspartate specific proteinases 12,Caspase-12 ELISA Kit
201-12-0763 96 tests
EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Caspase-12
RA15048 100 ug
EUR 461

Caspase-12 Antibody
24119-100ul 100ul
EUR 390

Caspase-12 Antibody
24120-100ul 100ul
EUR 390

Caspase-12 Antibody
2325-002mg 0.02 mg
EUR 171.82
Description: Caspase-12 Antibody: Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues.

Caspase-12 Antibody
2325-01mg 0.1 mg
EUR 436.42
Description: Caspase-12 Antibody: Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues.

Caspase-12 Antibody
2327-002mg 0.02 mg
EUR 171.82
Description: Caspase-12 Antibody: Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta.

Caspase-12 Antibody
2327-01mg 0.1 mg
EUR 436.42
Description: Caspase-12 Antibody: Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta.

Caspase 12 antibody
20R-1513 100 ug
EUR 673
Description: Rabbit polyclonal Caspase 12 antibody

Caspase 12 antibody
70R-11740 100 ug
EUR 460
Description: Rabbit polyclonal Caspase 12 antibody

Caspase 12 antibody
70R-51166 100 ul
EUR 244
Description: Purified Polyclonal Caspase 12 antibody

Caspase-12 Antibody
3282-100
EUR 354

Caspase-12 Antibody
3282-30T
EUR 146

Recombinant Caspase 12 (CASP12)
4-RPA682Mu01
  • EUR 467.36
  • EUR 228.00
  • EUR 1477.60
  • EUR 559.20
  • EUR 1018.40
  • EUR 376.00
  • EUR 3544.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Caspase 12 expressed in: E.coli

Recombinant Caspase 12 (CASP12)
4-RPA682Ra01
  • EUR 494.24
  • EUR 235.00
  • EUR 1578.40
  • EUR 592.80
  • EUR 1085.60
  • EUR 394.00
  • EUR 3796.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Caspase 12 expressed in: E.coli

Polyclonal Caspase-12 Antibody
APR00058G 0.1mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-12 . This antibody is tested and proven to work in the following applications:

Polyclonal Caspase-12 Antibody
APR06275G 0.1 mg
EUR 659
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-12 . This antibody is tested and proven to work in the following applications:

Polyclonal Caspase-12 Antibody
APR06276G 0.1 mg
EUR 659
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-12 . This antibody is tested and proven to work in the following applications:

Caspase-12 Antibody (Large)
24208-100ul 100ul
EUR 390

Caspase-12 Antibody (Small)
24209-100ul 100ul
EUR 390

Anti-Caspase-12 Antibody
A04700 100ug
EUR 471
Description: Rabbit Polyclonal Caspase-12 Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat.

Caspase 12 Polyclonal Antibody
ABP50853-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of Caspase 12 from Human. This Caspase 12 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Caspase12

Caspase 12 Polyclonal Antibody
ABP50853-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of Caspase 12 from Human. This Caspase 12 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Caspase12

Caspase 12 Polyclonal Antibody
ABP50853-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of Caspase 12 from Human. This Caspase 12 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Caspase12

Caspase 12 (CASP12) Antibody
20-abx129818
  • EUR 411.00
  • EUR 133.00
  • EUR 1135.00
  • EUR 551.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Caspase 12 (CASP12) Antibody
20-abx111421
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Caspase 12 (CASP12) Antibody
20-abx318255
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Caspase 12 (Casp12) Antibody
20-abx318989
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Caspase 12 (CASP12) Antibody
20-abx100899
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Caspase-12 Rabbit pAb
A0217-100ul 100 ul
EUR 308

Caspase-12 Rabbit pAb
A0217-200ul 200 ul
EUR 459

Caspase-12 Rabbit pAb
A0217-20ul 20 ul
EUR 183

Caspase-12 Rabbit pAb
A0217-50ul 50 ul
EUR 223

Caspase 12 (CASP12) Antibody
abx026563-400ul 400 ul
EUR 523

Caspase 12 (CASP12) Antibody
abx026563-80l 80 µl
EUR 286

Caspase 12 (CASP12) Antibody
20-abx213378
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Caspase 12 (CASP12) Antibody
20-abx210324
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Caspase 12 (CASP12) Antibody
abx216233-100ug 100 ug
EUR 439

Caspase 12 (CASP12) Antibody
20-abx324638
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

anti- Caspase 12 antibody
FNab01286 100µg
EUR 505.25
Description: Antibody raised against Caspase 12

Caspase 12 Assay Kit
55R-1290 25 assays
EUR 328
Description: Assay Kit for detection of Capase 12 activity in the research laboratory

Caspase-12 Antibody (Large)
3195-002mg 0.02 mg
EUR 171.82
Description: Caspase-12 Antibody: (Large)Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the main, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues.

Caspase-12 Antibody (Large)
3195-01mg 0.1 mg
EUR 436.42
Description: Caspase-12 Antibody: (Large)Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the main, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues.

Caspase-12 Antibody (Small)
3197-002mg 0.02 mg
EUR 171.82
Description: Caspase-12 Antibody: (Small)Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the main, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues.

Caspase-12 Antibody (Small)
3197-01mg 0.1 mg
EUR 436.42
Description: Caspase-12 Antibody: (Small)Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the main, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues.

Anti-Caspase 12 antibody
PAab01286 100 ug
EUR 355

99445-12 DCT 12 X 75MM
99445-12 250/pk
EUR 67
Description: Disposable Culture Tubes; DCT's, CGW

Human Caspase 12,Casp-12 ELISA Kit
CN-03708H1 96T
EUR 486

Human Caspase 12,Casp-12 ELISA Kit
CN-03708H2 48T
EUR 336

Human Caspase peptide-17(Caspase peptide-17)
QY-E05408 96T
EUR 361

Anti-Caspase-12/CASP12 Antibody
PA2103 100ug/vial
EUR 334

Anserini Caspase-12 ELISA Kit
EAC0697 96Tests
EUR 521

Rat Caspase-12 ELISA Kit
ERC0697 96Tests
EUR 521

Rabbit Caspase-12 ELISA Kit
ERTC0697 96Tests
EUR 521

Mouse Caspase-12 ELISA Kit
EMC0697 96Tests
EUR 521

Porcine Caspase-12 ELISA Kit
EPC0697 96Tests
EUR 521

Human Caspase-12 ELISA Kit
EHC0697 96Tests
EUR 521

Canine Caspase-12 ELISA Kit
ECC0697 96Tests
EUR 521

Goat Caspase-12 ELISA Kit
EGTC0697 96Tests
EUR 521

Bovine Caspase-12 ELISA Kit
EBC0697 96Tests
EUR 521

Polyclonal Caspase-12 Antibody (Large)
APR06327G 0.1 mg
EUR 659
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-12 (Large). This antibody is tested and proven to work in the following applications:

Polyclonal Caspase-12 Antibody (Small)
APR06328G 0.1 mg
EUR 659
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-12 (Small). This antibody is tested and proven to work in the following applications:

Caspase 12 (Casp12) Antibody (HRP)
20-abx318990
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Caspase 12 (Casp12) Antibody (FITC)
20-abx318991
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Caspase 12 (Casp12) Antibody (Biotin)
20-abx318992
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Caspase 12 (CASP12) Antibody (HRP)
20-abx316303
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Caspase 12 (CASP12) Antibody (FITC)
20-abx316304
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Caspase 12 (CASP12) Antibody (Biotin)
20-abx316305
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Rat Caspase 12 (CASP12) Protein
20-abx065753
  • EUR 690.00
  • EUR 286.00
  • EUR 2124.00
  • EUR 815.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Caspase 12 (CASP12) Protein
20-abx167225
  • EUR 648.00
  • EUR 272.00
  • EUR 1998.00
  • EUR 773.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Caspase-12 Fluorometric Assay Kit
K2150-100 100 assays
EUR 529

Caspase-12 Fluorometric Assay Kit
K2150-25 25 assays
EUR 251

Caspase 12 ELISA KIT|Human
EF008399 96 Tests
EUR 689

Rat Caspase 12 ELISA kit
E02C0690-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Caspase 12 ELISA kit
E02C0690-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Caspase 12 ELISA kit
E02C0690-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Caspase 12 ELISA kit
E09C0690-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Monkey Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Caspase 12 ELISA kit
E09C0690-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Monkey Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Caspase 12 ELISA kit
E09C0690-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Monkey Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Caspase 12 ELISA kit
E03C0690-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Mouse Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Caspase 12 ELISA kit
E03C0690-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Mouse Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Caspase 12 ELISA kit
E03C0690-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Mouse Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Caspase 12 ELISA kit
E01C0690-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Human Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Caspase 12 ELISA kit
E01C0690-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Human Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Caspase 12 ELISA kit
E01C0690-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Human Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Caspase 12 ELISA kit
E07C0690-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Porcine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Caspase 12 ELISA kit
E07C0690-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Porcine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Caspase 12 ELISA kit
E07C0690-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Porcine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Caspase 12 ELISA kit
E06C0690-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Goat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Caspase 12 ELISA kit
E06C0690-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Goat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Caspase 12 ELISA kit
E06C0690-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Goat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Caspase-12 Fluorometric Assay Kit
K139-100
EUR 501

Caspase-12 Fluorometric Assay Kit
K139-25
EUR 256

Caspase-12 Substrate ATAD-AFC
1117-1000
EUR 1088

Caspase-12 Substrate ATAD-AFC
1117-200
EUR 436

Rabbit Caspase 12 ELISA kit
E04C0690-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rabbit Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Caspase 12 ELISA kit
E04C0690-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rabbit Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Caspase 12 ELISA kit
E04C0690-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rabbit Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Caspase 12 ELISA kit
E08C0690-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Canine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Caspase 12 ELISA kit
E08C0690-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Canine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Caspase 12 ELISA kit
E08C0690-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Canine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Individual Reaction Mix 12
G065-12 200 reactions
EUR 167

Caspase-9 Peptide
2071P 0.05 mg
EUR 164.75
Description: (IN1) Caspase-9 peptide

Caspase-9 Peptide
2073P 0.05 mg
EUR 164.75
Description: (IN2) Caspase-9 peptide

Caspase-13 Peptide
2245P 0.05 mg
EUR 164.75
Description: Caspase-13 peptide

Caspase-14 Peptide
2509P 0.05 mg
EUR 164.75
Description: (CT) Caspase-14 peptide

Caspase-3 Peptide
3445P 0.05 mg
EUR 164.75
Description: (IN) Caspase-3 peptide

Caspase-2 Peptide
3447P 0.05 mg
EUR 164.75
Description: (NT) Caspase-2 peptide

Caspase-4 Peptide
3451P 0.05 mg
EUR 164.75
Description: (NT) Caspase-4 peptide

Caspase-4 Peptide
3453P 0.05 mg
EUR 164.75
Description: (IN) Caspase-4 peptide

Caspase-5 Peptide
3455P 0.05 mg
EUR 164.75
Description: (NT) Caspase-5 peptide

Caspase-5 Peptide
3457P 0.05 mg
EUR 164.75
Description: (IN) Caspase-5 peptide

Caspase-1 Peptide
3459P 0.05 mg
EUR 164.75
Description: (CT) Caspase-1 peptide

Caspase-1 Peptide
3463P 0.05 mg
EUR 164.75
Description: (IN) Caspase-1 peptide

Caspase-7 Peptide
3465P 0.05 mg
EUR 164.75
Description: (CT) Caspase-7 peptide

Caspase-7 Peptide
3467P 0.05 mg
EUR 164.75
Description: (NT) Caspase-7 peptide

Caspase-6 Peptide
3469P 0.05 mg
EUR 164.75
Description: (IN) Caspase-6 peptide

Caspase-6 Peptide
3471P 0.05 mg
EUR 164.75
Description: (IN) Caspase-6 peptide

Caspase-8 Peptide
3473P 0.05 mg
EUR 164.75
Description: (CT) Caspase-8 peptide

Caspase-8 Peptide
3475P 0.05 mg
EUR 164.75
Description: (CT) Caspase-8 peptide

Caspase 6 Peptide
43-365P 0.1 mg
EUR 338

Caspase-10 Peptide
1128P 0.05 mg
EUR 164.75
Description: (CT) Caspase-10 peptide

Human 12-lipoxygenase,LOX-12 ELISA Kit
201-12-0949 96 tests
EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.
Conclusions: Calcium phosphate coatings stimulate cell proliferation at early levels of fracture restoration and apoptotic cell loss of life at later levels. Coating parts could present positional data guiding the differentiation of mesenchymal stromal cells. A change within the exercise of apoptotic elements, osteocalcin, and CD44 is brought on by gene induction in response to the diffusion of calcium phosphate compounds from coating to surrounding tissue.
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