Hesperidin (HD), a citrus bioflavonoid possesses quite a lot of organic actions together with antioxidant, anti-inflammatory, anti-apoptotic and anti-carcinogenic properties. Within the current examine, we investigated the impact of HD remedy on N,N’-dimethylhydrazine (DMH) induced oxidative stress, irritation, apoptosis and goblet cell disintegration within the colon of Wistar rats. Administration of HD was accomplished at two doses (100 and 200 mg/kg physique weight) orally to rats each day for <em>14</em> days adopted by a single subcutaneous injection of DMH (40 mg/kg physique weight) on the <em>14</em>th day and subsequent day animals had been sacrificed.
The protecting potential of HD towards colon toxicity was measured by membrane oxidation, antioxidant standing, inflammatory and apoptotic markers expression, and histological adjustments. Outcomes demonstrated that HD inhibited DMH mediated oxidative harm by diminishing the extent of peroxidation of lipids and rising the exercise of superoxide dismutase, catalase, diminished glutathione, glutathione peroxidase, glutathione-s-transferase, and glutathione reductase. Furthermore, HD attenuated inflammatory (NF-кB, IL-6, and COX-2) and apoptotic (p38-MAPK, p53, and <em>caspase</em>-3) markers expression.
HD additionally attenuated the DMH induced goblet cell disintegration and restored histoarchitecture of the colon. The outcomes of the current examine exhibit that HD effectively protects towards DMH induced colon toxicity by modulating oxidative stress, irritation, and apoptosis.
Molecular subtype-specific responses of colon most cancers cells to the SMAC mimetic Birinapant
Colorectal most cancers is a molecularly heterogeneous illness. Responses to genotoxic chemotherapy within the adjuvant or palliative setting differ drastically between sufferers, and colorectal most cancers cells typically resist chemotherapy by evading apoptosis. Antagonists of an inhibitor of apoptosis proteins (IAPs) can restore faulty apoptosis signaling by degrading cIAP1 and cIAP2 proteins and by inhibition of XIAP. Because of the a number of molecular mechanisms-of-action of those targets, responses to IAP antagonist could differ between molecularly distinct colon most cancers cells. On this examine, responses to the IAP antagonist Birinapant and oxaliplatin/5-fluorouracil (5-FU) had been investigated in <em>14</em> colon most cancers cell strains, representing the consensus molecular subtypes (CMS). Therapy with Birinapant alone didn’t lead to a considerable enhance in apoptotic cells on this cell line panel.
Annexin-V/PI assays quantified by circulate cytometry and high-content screening confirmed that Birinapant elevated responses of CMS1 and partially CMS3 cell strains to oxaliplatin/5-FU, whereas CMS2 cells weren’t successfully sensitized. FRET-based imaging of <em>caspase</em>-Eight and -Three activation validated these variations on the single-cell degree, with CMS1 cells displaying sustained activation of <em>caspase</em>-8-like exercise throughout Birinapant and oxaliplatin/5-FU co-treatment, in the end activating the intrinsic mitochondrial apoptosis pathway. In CMS2 cell strains, Birinapant exhibited synergistic results together with TNFα, suggesting that Birinapant can restore extrinsic apoptosis signaling within the context of inflammatory indicators on this subtype. To discover this additional, we co-cultured CMS2 and CMS1 colon most cancers cells with peripheral blood mononuclear cells. We noticed elevated cell loss of life throughout Birinapant single remedy in these co-cultures, which was abrogated by anti-TNFα-neutralizing antibodies.
Collectively, our examine demonstrates that IAP inhibition is a promising modulator of response to oxaliplatin/5-FU in
colorectal cancers of the CMS1 subtype, and will present promise as within the CMS2 subtype, suggesting that molecular subtyping could assist as a affected person stratification software for IAP antagonists on this illness.

Protective effect of hesperidin against N,N’-dimethylhydrazine induced oxidative stress, inflammation, and apoptotic response in the colon of Wistar rats
The impact of calcium phosphate biodegradable coatings of titanium implants on cell differentiation and apoptosis in rat bone tissue after experimental fracture
Background: The effectiveness of bone restore is set by the stability of proliferative and harmful elements within the fracture union web site. It may be enhanced through the use of varied nanostructured supplies possessing osteoinductive properties, particularly titanium implants with biodegradable calcium phosphate coatings. The consequences of those coatings on the state of stem cells, their differentiation and distribution within the restore zone is unknown.
Goal: To check the dynamics of proliferation, differentiation, and apoptosis of stem cells after experimental fracture adopted by implantation of titanium implants with calcium phosphate coatings
The localization of proliferation (PCNA) and differentiation (CD44 and osteocalcin) elements and apoptotic molecules (MDM2, p53, <em>caspase</em>-3) was studied in a rat femoral fracture mannequin with implant placement. Titanium implant screws with bioactive calcium phosphate and hydroxyapatite coatings fashioned by plasma electrolytic oxidation had been used within the examine. Experimental rats had been organized into three teams (15 animals per group): management group; rats implanted with uncoated implants; and rats implanted with coated implants. Management rats had been topic to the same fracture as experimental ones and had been allowed to heal conservatively. Rats from all teams had been sampled on days 7, <em>14</em>, and 30 after harm.
Low-differentiated PCNA-, osteocalcin-, and CD44-immunopositive cells had been localized across the implant within the internal layer of the periosteum, layer of outer circumferential lamellae, and connective tissue lining of haversian canals. The spatial density of cells expressing the above proliferation and differentiation elements, in addition to that of MDM2-immunoreactive cells, elevated on day 7 and decreased by day 30 after harm. The spatial density of apoptotic cells reached the utmost on day <em>14</em> after harm. They had been primarily discovered within the internal layer of the periosteum and outer circumferential lamellae. p53- and <em>caspase</em>-3-positive cells occurred on the floor of the concentric lamellae surrounding haversian canals and below the periosteum. Their spatial density decreased by day 30 after harm.
Caspase-12 Peptide (Large) |
3195P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: Caspase-12 peptide (Large) |
Caspase-12 Peptide (Small) |
3197P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: Caspase-12 peptide (Small) |
Caspase 12 Blocking Peptide |
33R-10701 |
Fitzgerald |
50 ug |
EUR 229.2 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of Caspase 12 antibody, catalog no. 70R-11740 |
Caspase 12 Blocking Peptide |
33R-10465 |
Fitzgerald |
50 ug |
EUR 418.8 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of Caspase 12 antibody, catalog no. 20R-1513 |
Caspase 12 Blocking Peptide |
20-abx064041 |
Abbexa |
|
|
|
Caspase-12 Blocking Peptide |
3282BP-50 |
Biovision |
each |
EUR 183.6 |
Caspase 12 (Caspase 12) Antibody |
20-abx007974 |
Abbexa |
-
EUR 360.00
-
EUR 526.80
-
EUR 226.80
|
|
|
Caspase 12 (Caspase 12) Antibody |
abx231286-100ug |
Abbexa |
100 ug |
EUR 577.2 |
|
Caspase 12 (Caspase 12) Antibody |
abx432451-200ul |
Abbexa |
200 ul |
EUR 460.8 |
|
Human cysteinyl aspartate specific proteinases 12,Caspase-12 ELISA Kit |
201-12-0763 |
SunredBio |
96 tests |
EUR 528 |
|
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
Caspase-12 |
RA15048 |
Neuromics |
100 ug |
EUR 553.2 |
Caspase 12 antibody |
70R-11740 |
Fitzgerald |
100 ug |
EUR 552 |
Description: Rabbit polyclonal Caspase 12 antibody |
Caspase 12 antibody |
70R-51166 |
Fitzgerald |
100 ul |
EUR 292.8 |
Description: Purified Polyclonal Caspase 12 antibody |
Caspase 12 antibody |
20R-1513 |
Fitzgerald |
100 ug |
EUR 807.6 |
Description: Rabbit polyclonal Caspase 12 antibody |
Caspase-12 Antibody |
2325-002mg |
ProSci |
0.02 mg |
EUR 206.18 |
|
Description: Caspase-12 Antibody: Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues. |
Caspase-12 Antibody |
2325-01mg |
ProSci |
0.1 mg |
EUR 523.7 |
|
Description: Caspase-12 Antibody: Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues. |
Caspase-12 Antibody |
2327-002mg |
ProSci |
0.02 mg |
EUR 206.18 |
|
Description: Caspase-12 Antibody: Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. |
Caspase-12 Antibody |
2327-01mg |
ProSci |
0.1 mg |
EUR 523.7 |
|
Description: Caspase-12 Antibody: Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. |
Caspase-12 Antibody |
24119-100ul |
SAB |
100ul |
EUR 468 |
Caspase-12 Antibody |
24120-100ul |
SAB |
100ul |
EUR 468 |
Caspase-12 Antibody |
3282-100 |
Biovision |
each |
EUR 424.8 |
Caspase-12 Antibody |
3282-30T |
Biovision |
each |
EUR 175.2 |
Caspase 12 Assay Kit |
55R-1290 |
Fitzgerald |
25 assays |
EUR 393.6 |
Description: Assay Kit for detection of Capase 12 activity in the research laboratory |
Caspase-12 Rabbit pAb |
A0217-100ul |
Abclonal |
100 ul |
EUR 369.6 |
Caspase-12 Rabbit pAb |
A0217-200ul |
Abclonal |
200 ul |
EUR 550.8 |
Caspase-12 Rabbit pAb |
A0217-20ul |
Abclonal |
20 ul |
EUR 219.6 |
Caspase-12 Rabbit pAb |
A0217-50ul |
Abclonal |
50 ul |
EUR 267.6 |
Anti-Caspase-12 Antibody |
A04700 |
BosterBio |
100ug |
EUR 565.2 |
Description: Rabbit Polyclonal Caspase-12 Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat. |
Caspase-12 Antibody (Large) |
3195-002mg |
ProSci |
0.02 mg |
EUR 206.18 |
|
Description: Caspase-12 Antibody: (Large)Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the main, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues. |
Caspase-12 Antibody (Large) |
3195-01mg |
ProSci |
0.1 mg |
EUR 523.7 |
|
Description: Caspase-12 Antibody: (Large)Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the main, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues. |
Caspase-12 Antibody (Small) |
3197-002mg |
ProSci |
0.02 mg |
EUR 206.18 |
|
Description: Caspase-12 Antibody: (Small)Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the main, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues. |
Caspase-12 Antibody (Small) |
3197-01mg |
ProSci |
0.1 mg |
EUR 523.7 |
|
Description: Caspase-12 Antibody: (Small)Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the main, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues. |
Caspase-12 Antibody (Large) |
24208-100ul |
SAB |
100ul |
EUR 468 |
Caspase-12 Antibody (Small) |
24209-100ul |
SAB |
100ul |
EUR 468 |
Caspase 12 (CASP12) Antibody |
20-abx100899 |
Abbexa |
-
EUR 510.00
-
EUR 159.60
-
EUR 1412.40
-
EUR 693.60
-
EUR 393.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Caspase 12 Polyclonal Antibody |
ABP50853-003ml |
Abbkine |
0.03ml |
EUR 189.6 |
|
Description: A polyclonal antibody for detection of Caspase 12 from Human. This Caspase 12 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Caspase12 |
Caspase 12 Polyclonal Antibody |
ABP50853-01ml |
Abbkine |
0.1ml |
EUR 346.8 |
|
Description: A polyclonal antibody for detection of Caspase 12 from Human. This Caspase 12 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Caspase12 |
Caspase 12 Polyclonal Antibody |
ABP50853-02ml |
Abbkine |
0.2ml |
EUR 496.8 |
|
Description: A polyclonal antibody for detection of Caspase 12 from Human. This Caspase 12 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Caspase12 |
Caspase 12 (CASP12) Antibody |
20-abx111421 |
Abbexa |
|
|
|
Caspase 12 (CASP12) Antibody |
20-abx129818 |
Abbexa |
-
EUR 493.20
-
EUR 159.60
-
EUR 1362.00
-
EUR 661.20
-
EUR 376.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Caspase 12 (CASP12) Antibody |
abx026563-400ul |
Abbexa |
400 ul |
EUR 627.6 |
|
Caspase 12 (CASP12) Antibody |
abx026563-80l |
Abbexa |
80 µl |
EUR 343.2 |
|
Caspase 12 (CASP12) Antibody |
20-abx210324 |
Abbexa |
|
|
|
Caspase 12 (CASP12) Antibody |
abx216233-100ug |
Abbexa |
100 ug |
EUR 526.8 |
|
Caspase 12 (CASP12) Antibody |
20-abx324638 |
Abbexa |
|
|
|
Caspase 12 (CASP12) Antibody |
20-abx318255 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Caspase 12 (Casp12) Antibody |
20-abx318989 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Caspase 12 (CASP12) Antibody |
20-abx213378 |
Abbexa |
|
|
|
Polyclonal Caspase-12 Antibody |
APR00058G |
Leading Biology |
0.1mg |
EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-12 . This antibody is tested and proven to work in the following applications: |
Polyclonal Caspase-12 Antibody |
APR06275G |
Leading Biology |
0.1 mg |
EUR 790.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-12 . This antibody is tested and proven to work in the following applications: |
Polyclonal Caspase-12 Antibody |
APR06276G |
Leading Biology |
0.1 mg |
EUR 790.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-12 . This antibody is tested and proven to work in the following applications: |
anti- Caspase 12 antibody |
FNab01286 |
FN Test |
100µg |
EUR 606.3 |
|
Description: Antibody raised against Caspase 12 |
Recombinant Caspase 12 (CASP12) |
4-RPA682Mu01 |
Cloud-Clone |
-
EUR 560.83
-
EUR 273.60
-
EUR 1773.12
-
EUR 671.04
-
EUR 1222.08
-
EUR 451.20
-
EUR 4252.80
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Mouse Caspase 12 expressed in: E.coli |
Recombinant Caspase 12 (CASP12) |
4-RPA682Ra01 |
Cloud-Clone |
-
EUR 593.09
-
EUR 282.00
-
EUR 1894.08
-
EUR 711.36
-
EUR 1302.72
-
EUR 472.80
-
EUR 4555.20
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Rat Caspase 12 expressed in: E.coli |
99445-12 DCT 12 X 75MM |
99445-12 |
CORNING |
250/pk |
EUR 80.4 |
Description: Disposable Culture Tubes; DCT's, CGW |
Human Caspase 12,Casp-12 ELISA Kit |
CN-03708H1 |
ChemNorm |
96T |
EUR 583.2 |
Human Caspase 12,Casp-12 ELISA Kit |
CN-03708H2 |
ChemNorm |
48T |
EUR 403.2 |
Caspase-10 Peptide |
1128P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (CT) Caspase-10 peptide |
Caspase 6 Peptide |
43-365P |
ProSci |
0.1 mg |
EUR 405.6 |
Caspase-9 Peptide |
2071P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (IN1) Caspase-9 peptide |
Caspase-9 Peptide |
2073P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (IN2) Caspase-9 peptide |
Caspase-3 Peptide |
3445P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (IN) Caspase-3 peptide |
Caspase-2 Peptide |
3447P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (NT) Caspase-2 peptide |
Caspase-4 Peptide |
3451P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (NT) Caspase-4 peptide |
Caspase-4 Peptide |
3453P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (IN) Caspase-4 peptide |
Caspase-5 Peptide |
3455P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (NT) Caspase-5 peptide |
Caspase-5 Peptide |
3457P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (IN) Caspase-5 peptide |
Caspase-1 Peptide |
3459P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (CT) Caspase-1 peptide |
Caspase-1 Peptide |
3463P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (IN) Caspase-1 peptide |
Caspase-7 Peptide |
3465P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (CT) Caspase-7 peptide |
Caspase-7 Peptide |
3467P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (NT) Caspase-7 peptide |
Caspase-6 Peptide |
3469P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (IN) Caspase-6 peptide |
Caspase-6 Peptide |
3471P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (IN) Caspase-6 peptide |
Caspase-8 Peptide |
3473P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (CT) Caspase-8 peptide |
Caspase-8 Peptide |
3475P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (CT) Caspase-8 peptide |
Caspase-13 Peptide |
2245P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: Caspase-13 peptide |
Caspase-14 Peptide |
2509P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (CT) Caspase-14 peptide |
Mouse Caspase 12 (CASP12) Protein |
20-abx167225 |
Abbexa |
-
EUR 777.60
-
EUR 326.40
-
EUR 2397.60
-
EUR 927.60
-
EUR 560.40
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Rat Caspase 12 (CASP12) Protein |
20-abx065753 |
Abbexa |
-
EUR 828.00
-
EUR 343.20
-
EUR 2548.80
-
EUR 978.00
-
EUR 594.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Caspase 12 (Casp12) Antibody (HRP) |
20-abx318990 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Caspase 12 (Casp12) Antibody (FITC) |
20-abx318991 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Caspase 12 (Casp12) Antibody (Biotin) |
20-abx318992 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Caspase 12 (CASP12) Antibody (HRP) |
20-abx316303 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Caspase 12 (CASP12) Antibody (FITC) |
20-abx316304 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Caspase 12 (CASP12) Antibody (Biotin) |
20-abx316305 |
Abbexa |
-
EUR 493.20
-
EUR 2214.00
-
EUR 718.80
-
EUR 218.40
-
EUR 360.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Polyclonal Caspase-12 Antibody (Large) |
APR06327G |
Leading Biology |
0.1 mg |
EUR 790.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-12 (Large). This antibody is tested and proven to work in the following applications: |
Polyclonal Caspase-12 Antibody (Small) |
APR06328G |
Leading Biology |
0.1 mg |
EUR 790.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-12 (Small). This antibody is tested and proven to work in the following applications: |
Goat Caspase 12 ELISA kit |
E06C0690-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Goat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Caspase 12 ELISA kit |
E06C0690-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Goat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Caspase 12 ELISA kit |
E06C0690-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Goat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Caspase 12 ELISA kit |
E04C0690-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Caspase 12 ELISA kit |
E04C0690-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Caspase 12 ELISA kit |
E04C0690-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Porcine Caspase-12 ELISA Kit |
EPC0697 |
Abclonal |
96Tests |
EUR 625.2 |
Rabbit Caspase-12 ELISA Kit |
ERTC0697 |
Abclonal |
96Tests |
EUR 625.2 |
Rat Caspase-12 ELISA Kit |
ERC0697 |
Abclonal |
96Tests |
EUR 625.2 |
Mouse Caspase-12 ELISA Kit |
EMC0697 |
Abclonal |
96Tests |
EUR 625.2 |
Human Caspase-12 ELISA Kit |
EHC0697 |
Abclonal |
96Tests |
EUR 625.2 |
Goat Caspase-12 ELISA Kit |
EGTC0697 |
Abclonal |
96Tests |
EUR 625.2 |
Dog Caspase 12 ELISA kit |
E08C0690-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Canine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Caspase 12 ELISA kit |
E08C0690-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Canine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Caspase 12 ELISA kit |
E08C0690-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Canine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Caspase 12 ELISA kit |
E09C0690-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Monkey Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Caspase 12 ELISA kit |
E09C0690-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Monkey Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Caspase 12 ELISA kit |
E09C0690-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Monkey Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Caspase 12 ELISA kit |
E01C0690-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Human Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Caspase 12 ELISA kit |
E01C0690-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Human Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Caspase 12 ELISA kit |
E01C0690-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Human Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Canine Caspase-12 ELISA Kit |
ECC0697 |
Abclonal |
96Tests |
EUR 625.2 |
Anserini Caspase-12 ELISA Kit |
EAC0697 |
Abclonal |
96Tests |
EUR 625.2 |
Bovine Caspase-12 ELISA Kit |
EBC0697 |
Abclonal |
96Tests |
EUR 625.2 |
Rat Caspase 12 ELISA kit |
E02C0690-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Rat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Caspase 12 ELISA kit |
E02C0690-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Rat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Caspase 12 ELISA kit |
E02C0690-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Rat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Caspase 12 ELISA kit |
E03C0690-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Mouse Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Caspase 12 ELISA kit |
E03C0690-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Mouse Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Caspase 12 ELISA kit |
E03C0690-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Mouse Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Caspase 12 ELISA kit |
E07C0690-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Porcine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Caspase 12 ELISA kit |
E07C0690-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Porcine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Caspase 12 ELISA kit |
E07C0690-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Porcine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Caspase-12 Fluorometric Assay Kit |
K2150-100 |
ApexBio |
100 assays |
EUR 634.8 |
Caspase-12 Fluorometric Assay Kit |
K2150-25 |
ApexBio |
25 assays |
EUR 301.2 |
Anti-Caspase-12/CASP12 Antibody |
PA2103 |
BosterBio |
100ug/vial |
EUR 400.8 |
Caspase-12 Fluorometric Assay Kit |
K139-100 |
Biovision |
each |
EUR 601.2 |
Caspase-12 Fluorometric Assay Kit |
K139-25 |
Biovision |
each |
EUR 307.2 |
Conclusions: Calcium phosphate coatings stimulate cell proliferation at early levels of fracture restoration and apoptotic cell loss of life at later levels. Coating parts could present positional data guiding the differentiation of mesenchymal stromal cells. A change within the exercise of apoptotic elements, osteocalcin, and CD44 is brought on by gene induction in response to the diffusion of calcium phosphate compounds from coating to surrounding tissue.