Copper nanoparticles (Cu-NPs) have been used more and more in varied merchandise and functions. Though latest research have reported that publicity to Cu-NPs results in organ accumulation and apparent toxicity, it stays unclear whether or not Cu-NPs will be translocated to and trigger injury within the uterus. On this examine, we investigated the potential for uterine harm and gene expression patterns in feminine rats uncovered to three.12, 6.25, or 12.5 mg/kg/d Cu-NPs through intraperitoneal injection for <em>14</em> consecutive days. The outcomes indicated that publicity to Cu-NPs led to vital decreases within the relative uterine weight coefficients and will increase in inflammatory cell infiltration, mitochondrial swelling and vacuolization, shortened and lowered endometrial epithelial cell microvilli, and apoptosis.
Moreover, publicity to Cu-NPs elevated malondialdehyde (MDA) accumulation and decreased superoxide dismutase (SOD) ranges. Sign transduction mechanism research indicated that publicity to Cu-NPs activated <em>caspases</em> 3, 8, and 9 and BH3 interacting area dying agonist (tBid), lowered B cell leukemia/lymphoma 2 (Bcl-2) expression, and elevated the expression of apoptotic peptidase activating issue 1 (Apaf-1), BCL2-associated X, apoptosis regulator (Bax), and cytochrome c. A microarray evaluation revealed vital alterations within the expression of 963 genes; of those, 622 had been upregulated and 341 had been downregulated. The outcomes of additional evaluations of some altered genes, together with matrix metallopeptidase 12 (Mmp12), utilizing quantitative RT-PCR agreed with the microarray findings. These outcomes present sturdy proof that Cu-NPs can set off each intrinsic and extrinsic apoptotic pathways to mediate uterine harm, leading to oxidative stress-related modifications in gene expression.
Beforehand, we confirmed that noxious stimulation of the tail produces quite a few detrimental results after spinal wire harm (SCI), together with an earlier onset and elevated magnitude of mechanical hypersensitivity. Increasing on these observations, this examine sought to find out whether or not localized peripheral irritation equally impacts the expression of mechanical hypersensitivity after SCI.
The Impact of Lengthy-Time period Administration of Fatty Acid Amide Hydrolase Inhibitor URB597 on Oxidative Metabolism within the Coronary heart of Rats with Main and Secondary Hypertension.
Fatty acid amide hydrolase (FAAH) inhibitor [3-(3-carbamoylphenyl)phenyl] N-cyclohexylcarbamate (URB597) might affect redox stability and blood stress by means of the modulation of endocannabinoids ranges. Due to this fact, this examine aimed to check modifications in oxidative metabolism and apoptosis within the hearts of rats with spontaneous hypertension (SHR) and secondary hypertension (11-deoxycorticosterone acetate; DOCA-salt rats) handled by URB597 through intraperitoneal injection for days. The outcomes confirmed that URB597 decreased the exercise of NADPH and xanthine oxidases in each teams of rats. Furthermore, within the coronary heart of SHR rats, URB597 led to a rise of enzymatic and nonenzymatic antioxidant exercise and ranges (catalase, vitamin C, glutathione/glutathione disulfide [GSH/GSSG]) and upregulation of the thioredoxin system; nonetheless, NRf2 expression was downregulated.
The alternative impact in relation to Nrf2 exercise and the thioredoxin system was noticed in DOCA-salt rats after URB597 administration. Regardless of enchancment in antioxidant parameters, URB597 enhanced oxidative modifications of phospholipids (4-hydroxynonenal and isoprostanes) and proteins (carbonyl teams) in SHR coronary heart, whereas 4-hydroxynonenal and carbonyl teams ranges decreased within the coronary heart of DOCA-salt rats. Obtained outcomes recommend that examined lipid mediators are concerned in peroxisome proliferator-activated receptors (PPAR)-independent and PPAR-dependent modulation of cardiac inflammatory reactions. Moreover, decreased expression of pro-apoptotic proteins (Bax and <em>caspase</em> Three and 9) was noticed after URB597 administration within the coronary heart of each teams of hypertensive rats, whereas expression of the antiapoptotic protein (Bcl-2) elevated in SHR rats.
Lengthy-term administration of URB597 altered cardiac redox standing relying on the kind of hypertension. URB597 enhanced oxidative metabolism and lowered pro-apoptotic components within the coronary heart of SHR rats, rising the chance of coronary heart metabolic issues prevalence or development.
Self-nanoemulsifying drug-delivery programs for potentiated anti-inflammatory exercise of diacerein.
UNASSIGNED
Efficient therapy of osteoarthritis necessitates each symptomatic aid and hindrance of joint degeneration development. Non-steroidal anti-inflammatory medicine allow symptomatic aid solely and might trigger mucosal harm within the intestine. Earlier than absorption, diacerein (Dcn) is transformed into rhein that counteracts cartilage degeneration with out affecting prostaglandin manufacturing. But, low solubility and laxative motion of unabsorbed rhein within the colon hindered its use. Thus, enhanced Dcn dissolution would enable absorption on the higher intestine bettering its bioavailability and probably abolishing the laxative motion.
UNASSIGNED
Due to this fact, self-nanoemulsifying drug supply programs (SNEDDSs) with every of gelucire (Glc) and d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) at totally different drug:service weight ratios of 1:1, 1:2, 1:4, 1:6, 1:Eight and 1:10 had been ready by soften methodology and crammed into arduous gelatin capsules. The optimized binary programs had been chosen primarily based on strong state characterization, scanning electron microscopy (SEM) and in vitro analysis of the ready SNEDDSs as compared with their corresponding bodily mixtures (PMs) and Dcn. The optimized programs had been additional examined with respect to their morphology, measurement distribution and ζ-potential. Furthermore, the anti-inflammatory exercise of the optimized programs towards carrageenan-induced paw edema in rats was assessed by means of estimation of edema and edema inhibition percentages in addition to histopathological examination and immunohistochemical localization of tumor necrosis factor-alpha (TNF-α) and <em>caspase</em>-3.
UNASSIGNED
Considerably (P<0.05) enhanced in vitro drug launch was recorded for SNEDDSs with both service when in comparison with Dcn and the corresponding PMs. SNEDDSs primarily based on 1:10 Dcn:Glc and 1:Eight Dcn:TPGS confirmed considerably (P<0.05) lowered edema and irritation in addition to expression of TNF-α and caspase-Three relative to constructive management and Dcn pretreated teams.
FAM FLICA CASPASE-1 KIT (OKSA11275) |
OKSA11275 |
Aviva Systems Biology |
100 Tests |
EUR 1827.6 |
Description: Description of target: The FAM FLICATM Capase 1 kit uses a target sequence (YVAD) sandwiched between a green fluorescent label, FAM, and FMK to make a quick and flexible method to analyze active capases in apoptotic cells. These kits measure apoptosis by detecting active caspases in whole, living cells. They don't work by using antibodies or an ELISA. Instead, their methodology is based a unique cell-permeable and non-cytotoxic reagent called Fluorochrome Inhibitor of Caspases. These kits are suitable for cells in suspension, adherent cells, thin tissue sections (but not fixed or paraffin-embedded cells) from many species including mammalian, insect, and yeast. Different cell types, e.g. HeLa, primary neurons, macrophages and lymphocytes have also been successfully studied with these kits. ;Species reactivity: Human;Application: FC, IF;Assay info: ;Sensitivity: |
FAM FLICA CASPASE-2 KIT (OKSA11283) |
OKSA11283 |
Aviva Systems Biology |
100 Tests |
EUR 1593.6 |
Description: Description of target: FAM FLICAâ„¢ CASPASE-2 KIT;Species reactivity: ;Application: FC, IF;Assay info: ;Sensitivity: |
FAM FLICA CASPASE-3/7 KIT (OKSA11271) |
OKSA11271 |
Aviva Systems Biology |
100 Tests |
EUR 1828.8 |
Description: Description of target: The FAM FLICA™ Caspase 3 & 7 kit uses a quick and easy method to analyze active caspases in apoptotic cells.;Species reactivity: ;Application: FC, IF;Assay info: ;Sensitivity: |
FAM FLICAâ„¢ CASPASE-9 KIT (OKSA11278) |
OKSA11278 |
Aviva Systems Biology |
25 Tests |
EUR 709.2 |
Description: Description of target: FAM FLICAâ„¢ CASPASE-9 KIT;Species reactivity: ;Application: FC, IF;Assay info: ;Sensitivity: |
FAM FLICAâ„¢ CASPASE-9 KIT (OKSA11279) |
OKSA11279 |
Aviva Systems Biology |
100 Tests |
EUR 1828.8 |
Description: Description of target: FAM FLICAâ„¢ CASPASE-9 KIT;Species reactivity: ;Application: FC, IF;Assay info: ;Sensitivity: |
FAM FLICAâ„¢ CASPASE-6 KIT (OKSA11272) |
OKSA11272 |
Aviva Systems Biology |
25 Tests |
EUR 717.6 |
Description: Description of target: FAM FLICAâ„¢ CASPASE-6 KIT;Species reactivity: ;Application: FC, IF;Assay info: ;Sensitivity: |
FAM FLICAâ„¢ CASPASE-6 KIT (OKSA11273) |
OKSA11273 |
Aviva Systems Biology |
100 Tests |
EUR 1860 |
Description: Description of target: FAM FLICAâ„¢ CASPASE-6 KIT;Species reactivity: ;Application: FC, IF;Assay info: ;Sensitivity: |
FAM FLICAâ„¢ CASPASE-8 KIT (OKSA11276) |
OKSA11276 |
Aviva Systems Biology |
25 Tests |
EUR 709.2 |
Description: Description of target: FAM FLICAâ„¢ CASPASE-8 KIT;Species reactivity: ;Application: FC, IF;Assay info: ;Sensitivity: |
FAM FLICAâ„¢ CASPASE-8 KIT (OKSA11277) |
OKSA11277 |
Aviva Systems Biology |
100 Tests |
EUR 1828.8 |
Description: Description of target: FAM FLICAâ„¢ CASPASE-8 KIT;Species reactivity: ;Application: FC, IF;Assay info: ;Sensitivity: |
FAM FLICAâ„¢ CASPASE-2 KIT (OKSA11282) |
OKSA11282 |
Aviva Systems Biology |
25 Tests |
EUR 668.4 |
Description: Description of target: FAM FLICAâ„¢ CASPASE-2 KIT;Species reactivity: ;Application: FC, IF;Assay info: ;Sensitivity: |
FAM FLICAâ„¢ POLY CASPASE KIT (OKSA11268) |
OKSA11268 |
Aviva Systems Biology |
25 Tests |
EUR 709.2 |
Description: Description of target: FAM FLICAâ„¢ POLY CASPASE KIT;Species reactivity: ;Application: FC, IF;Assay info: ;Sensitivity: |
FAM FLICAâ„¢ POLY CASPASE KIT (OKSA11269) |
OKSA11269 |
Aviva Systems Biology |
100 Tests |
EUR 1828.8 |
Description: Description of target: FAM FLICAâ„¢ POLY CASPASE KIT;Species reactivity: ;Application: FC, IF;Assay info: ;Sensitivity: |
SR FLICAâ„¢ CASPASE-9 KIT (OKSA11301) |
OKSA11301 |
Aviva Systems Biology |
25 Tests |
EUR 724.8 |
Description: Description of target: SR FLICAâ„¢ CASPASE-9 KIT;Species reactivity: ;Application: FC, IF;Assay info: ;Sensitivity: |
SR FLICAâ„¢ CASPASE-9 KIT (OKSA11302) |
OKSA11302 |
Aviva Systems Biology |
100 Tests |
EUR 1884 |
Description: Description of target: SR FLICAâ„¢ CASPASE-9 KIT;Species reactivity: ;Application: FC, IF;Assay info: ;Sensitivity: |
SR FLICAâ„¢ POLY CASPASE KIT (OKSA11280) |
OKSA11280 |
Aviva Systems Biology |
25 Tests |
EUR 756 |
Description: Description of target: SR FLICAâ„¢ POLY CASPASE KIT;Species reactivity: ;Application: FC, IF;Assay info: ;Sensitivity: |
SR FLICAâ„¢ POLY CASPASE KIT (OKSA11281) |
OKSA11281 |
Aviva Systems Biology |
100 Tests |
EUR 1828.8 |
Description: Description of target: SR FLICAâ„¢ POLY CASPASE KIT;Species reactivity: ;Application: FC, IF;Assay info: ;Sensitivity: |
Caspase 9 Assay Kit |
20-abx299021 |
Abbexa |
|
|
|
Caspase 9 Assay Kit |
20-abx299035 |
Abbexa |
|
|
|
Rat Caspase-9,Casp-9 ELISA Kit |
CN-01708R1 |
ChemNorm |
96T |
EUR 542.4 |
Rat Caspase-9,Casp-9 ELISA Kit |
CN-01708R2 |
ChemNorm |
48T |
EUR 362.4 |
Rat Caspase-9, Casp-9 ELISA Kit |
CSB-E08863r-24T |
Cusabio |
1 plate of 24 wells |
EUR 198 |
|
Description: Quantitativesandwich ELISA kit for measuring Rat Caspase-9, Casp-9 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Rat Caspase-9, Casp-9 ELISA Kit |
1-CSB-E08863r |
Cusabio |
-
EUR 843.60
-
EUR 5811.60
-
EUR 3084.00
|
- 1 plate of 96 wells
- 10 plates of 96 wells each
- 5 plates of 96 wells each
|
|
Description: Quantitativesandwich ELISA kit for measuring Rat Caspase-9, Casp-9 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Mouse Caspase-9,Casp-9 ELISA Kit |
CN-02586M1 |
ChemNorm |
96T |
EUR 525.6 |
Mouse Caspase-9,Casp-9 ELISA Kit |
CN-02586M2 |
ChemNorm |
48T |
EUR 346.8 |
Human Caspase-9,Casp-9 ELISA Kit |
CN-03799H1 |
ChemNorm |
96T |
EUR 576 |
Human Caspase-9,Casp-9 ELISA Kit |
CN-03799H2 |
ChemNorm |
48T |
EUR 397.2 |
Human Caspase-9, Casp-9 ELISA Kit |
CSB-E08862h-24T |
Cusabio |
1 plate of 24 wells |
EUR 198 |
|
Description: Quantitativesandwich ELISA kit for measuring Human Caspase-9, Casp-9 in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Human Caspase-9, Casp-9 ELISA Kit |
1-CSB-E08862h |
Cusabio |
-
EUR 843.60
-
EUR 5811.60
-
EUR 3084.00
|
- 1 plate of 96 wells
- 10 plates of 96 wells each
- 5 plates of 96 wells each
|
|
Description: Quantitativesandwich ELISA kit for measuring Human Caspase-9, Casp-9 in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Mouse Caspase-9, Casp-9 ELISA Kit |
CSB-E08864m-24T |
Cusabio |
1 plate of 24 wells |
EUR 198 |
|
Description: Quantitativesandwich ELISA kit for measuring Mouse Caspase-9, Casp-9 in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Mouse Caspase-9, Casp-9 ELISA Kit |
1-CSB-E08864m |
Cusabio |
-
EUR 843.60
-
EUR 5811.60
-
EUR 3084.00
|
- 1 plate of 96 wells
- 10 plates of 96 wells each
- 5 plates of 96 wells each
|
|
Description: Quantitativesandwich ELISA kit for measuring Mouse Caspase-9, Casp-9 in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Rat caspase-9 ELISA Kit |
ERC0103 |
Abclonal |
96Tests |
EUR 625.2 |
Goat Caspase-9 ELISA Kit |
EGTC0103 |
Abclonal |
96Tests |
EUR 625.2 |
FAM FLICACASPASE-3/7 KIT (OKSA11270) |
OKSA11270 |
Aviva Systems Biology |
25 Tests |
EUR 709.2 |
Description: Description of target: Caspase FLICA™ kits measure apoptosis by detecting active caspases in whole, living cells. These kits do not work by using antibodies or as an ELISA. Instead, their methodology is based on a unique cell-permeable and non-cytotoxic reagent called the Fluorochrome Inhibitor of Caspases (FLICA). The FLICA™ reagent contains a caspase inhibitor sequence linked to a green (Carboxyfluorescein, FAM) fluorescent probe. The Caspase FLICA™ Kits are suitable for cells in suspension, adherent cells, thin tissue sections (but not fixed or paraffin-embedded cells) from many species including mammalian, insect and yeast. Different cell types, e.g. HeLa, primary neurons, macrophages and lymphocytes have also been successfully studied with these kits. This kit can be used with a flow cytometer, fluorescence microscope or a fluorescence plate reader using black microtitre plates. ;Species reactivity: ;Application: FC, IF;Assay info: ;Sensitivity: |
Mouse caspase-9 ELISA Kit |
EMC0103 |
Abclonal |
96Tests |
EUR 625.2 |
Caspase-9 (Human) ELISA Kit |
K4165-100 |
Biovision |
each |
EUR 966 |
Sheep Caspase-9 ELISA Kit |
ESC0103 |
Abclonal |
96Tests |
EUR 625.2 |
Human Caspase-9 ELISA Kit |
EHC0103 |
Abclonal |
96Tests |
EUR 625.2 |
Monkey Caspase-9 ELISA Kit |
EMKC0103 |
Abclonal |
96Tests |
EUR 625.2 |
Bovine Caspase-9 ELISA Kit |
EBC0103 |
Abclonal |
96Tests |
EUR 625.2 |
Rabbit Caspase-9 ELISA Kit |
ERTC0103 |
Abclonal |
96Tests |
EUR 625.2 |
Canine Caspase-9 ELISA Kit |
ECC0103 |
Abclonal |
96Tests |
EUR 625.2 |
Porcine Caspase-9 ELISA Kit |
EPC0103 |
Abclonal |
96Tests |
EUR 625.2 |
Chicken Caspase-9 ELISA Kit |
ECKC0103 |
Abclonal |
96Tests |
EUR 625.2 |
Rat Caspase 9 ELISA kit |
E02C0096-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A sandwich ELISA for quantitative measurement of Rat Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Caspase 9 ELISA kit |
E02C0096-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A sandwich ELISA for quantitative measurement of Rat Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Caspase 9 ELISA kit |
E02C0096-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A sandwich ELISA for quantitative measurement of Rat Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Caspase 9 Assay Kit, red |
KF17302 |
Neuromics |
25 Tests |
EUR 364.8 |
Dog Caspase 9 ELISA kit |
E08C0096-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A sandwich ELISA for quantitative measurement of Canine Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Caspase 9 ELISA kit |
E08C0096-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A sandwich ELISA for quantitative measurement of Canine Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Caspase 9 ELISA kit |
E08C0096-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A sandwich ELISA for quantitative measurement of Canine Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Caspase 9 ELISA kit |
E07C0096-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A sandwich ELISA for quantitative measurement of Porcine Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Caspase 9 ELISA kit |
E07C0096-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A sandwich ELISA for quantitative measurement of Porcine Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Caspase 9 ELISA kit |
E07C0096-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A sandwich ELISA for quantitative measurement of Porcine Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Caspase-9 Peptide |
2071P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (IN1) Caspase-9 peptide |
Caspase-9 Peptide |
2073P |
ProSci |
0.05 mg |
EUR 197.7 |
Description: (IN2) Caspase-9 peptide |
Caspase-9 Antibody |
6670-100 |
Biovision |
each |
EUR 405.6 |
Caspase-9 Antibody |
6670-30T |
Biovision |
each |
EUR 175.2 |
Caspase-9 Antibody |
48161-100ul |
SAB |
100ul |
EUR 399.6 |
Caspase-9 Antibody |
48161-50ul |
SAB |
50ul |
EUR 286.8 |
Caspase-9 Antibody |
48687-100ul |
SAB |
100ul |
EUR 399.6 |
Caspase-9 Antibody |
48687-50ul |
SAB |
50ul |
EUR 286.8 |
Caspase-9 Antibody |
49014-100ul |
SAB |
100ul |
EUR 399.6 |
Caspase-9 Antibody |
49014-50ul |
SAB |
50ul |
EUR 286.8 |
Caspase-9 Antibody |
24049-100ul |
SAB |
100ul |
EUR 468 |
Caspase-9 Antibody |
24050-100ul |
SAB |
100ul |
EUR 468 |
Caspase-9 Antibody |
2071-002mg |
ProSci |
0.02 mg |
EUR 206.18 |
|
Description: Caspase-9 Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. A novel member in the caspase family was recently identified and designated ICE-LAP6, Mch6, and Apaf-3. Caspase-9 and Apaf-1 bind to each other, which leads to caspase-9 activation. Caspase-9 is also activated by granzyme B and CPP32. Activated caspase-9 cleaves and activates caspase-3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis. Caspase-9 play a central role in cell death induced by a wide variety of apoptosis activators including TNFα, TRAIL, anti-CD-95, FADD, and TRADD. Caspase-9 is expressed in a variety of human tissues. |
Caspase-9 Antibody |
2071-01mg |
ProSci |
0.1 mg |
EUR 523.7 |
|
Description: Caspase-9 Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. A novel member in the caspase family was recently identified and designated ICE-LAP6, Mch6, and Apaf-3. Caspase-9 and Apaf-1 bind to each other, which leads to caspase-9 activation. Caspase-9 is also activated by granzyme B and CPP32. Activated caspase-9 cleaves and activates caspase-3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis. Caspase-9 play a central role in cell death induced by a wide variety of apoptosis activators including TNFα, TRAIL, anti-CD-95, FADD, and TRADD. Caspase-9 is expressed in a variety of human tissues. |
Caspase-9 Antibody |
2073-002mg |
ProSci |
0.02 mg |
EUR 206.18 |
|
Description: Caspase-9 Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. A novel member in the caspase family was recently identified and designated ICE-LAP6, Mch6, and Apaf-3. Caspase-9 and Apaf-1 bind to each other, which leads to caspase-9 activation. Caspase-9 is also activated by granzyme B and CPP32. Activated caspase-9 cleaves and activates caspase-3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis. Caspase-9 play a central role in cell death induced by a wide variety of apoptosis activators including TNFα, TRAIL, anti-CD-95, FADD, and TRADD. Caspase-9 is expressed in a variety of human tissues. |
Caspase-9 Antibody |
2073-01mg |
ProSci |
0.1 mg |
EUR 523.7 |
|
Description: Caspase-9 Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. A novel member in the caspase family was recently identified and designated ICE-LAP6, Mch6, and Apaf-3. Caspase-9 and Apaf-1 bind to each other, which leads to caspase-9 activation. Caspase-9 is also activated by granzyme B and CPP32. Activated caspase-9 cleaves and activates caspase-3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis. Caspase-9 play a central role in cell death induced by a wide variety of apoptosis activators including TNFα, TRAIL, anti-CD-95, FADD, and TRADD. Caspase-9 is expressed in a variety of human tissues. |
Caspase-9 Antibody |
3016-100 |
Biovision |
each |
EUR 405.6 |
Caspase-9 Antibody |
3016-30T |
Biovision |
each |
EUR 175.2 |
Caspase-9 Antibody |
3136-100 |
Biovision |
each |
EUR 392.4 |
Caspase-9 Antibody |
3136-30T |
Biovision |
each |
EUR 175.2 |
Caspase-9 Antibody |
3409-100 |
Biovision |
each |
EUR 379.2 |
Caspase-9 Antibody |
3409-30T |
Biovision |
each |
EUR 175.2 |
Caspase-9 Antibody |
F50929-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 140.25 |
Description: Caspase 9 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. |
Caspase-9 Antibody |
F50929-0.4ML |
NSJ Bioreagents |
0.4 ml |
EUR 322.15 |
Description: Caspase 9 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. |
Caspase-9 Antibody |
F50930-0.08ML |
NSJ Bioreagents |
0.08 ml |
EUR 140.25 |
Description: Caspase 9 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. |
Caspase-9 Antibody |
F50930-0.4ML |
NSJ Bioreagents |
0.4 ml |
EUR 322.15 |
Description: Caspase 9 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. |
Caspase-9 Antibody |
RQ6459 |
NSJ Bioreagents |
100ug |
EUR 356.15 |
Description: CASP9 is also known as MCH6 or APAF3. This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. |
Caspase-9 Antibody |
RQ6974 |
NSJ Bioreagents |
100 ug |
EUR 356.15 |
Description: CASP9 is also known as MCH6 or APAF3. This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. |
Caspase-9 Antibody |
R31745 |
NSJ Bioreagents |
100 ug |
EUR 356.15 |
Description: Caspase-9 is also known as MCH6 or APAF3. The CASP9 gene encodes a member of the cysteine-aspartic acid protease family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of Cytochrome Cand the Apoptotic peptidase activating factor 1. This step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. |
Caspase-9 Antibody |
R30673 |
NSJ Bioreagents |
100 ug |
EUR 356.15 |
Description: Caspase-9, also called APAF3, is an initiator caspase, encoded by the CASP9 gene. The gene is mapped to chromosome 1p36.3-p36.1 by FISH. CASP9 is identified as a member of the caspase family that participates in CASP3 activation in vitro. And it also regarded as the most upstream member of the apoptotic protease cascade that is triggered by Cytochrome C and dATP. The crystal structure of CASP9 is complex with the BIR3 in an inhibitory domain of XIAP at 2.4-angstrom resolution and the gene contains 9 exons and spans approximately 35 kb of genomic DNA. Caspase-9 and APAF1 bind to each other via their respective NH2-terminal CED-3 homologous domains in the presence of Cytochrome C and dATP, an event that leads to CASP9 activation. Activity increases dramatically upon association with the apoptosome complex. And the majority of CASP9 knockout mice died perinatally with a markedly enlarged and malformed cerebrum caused by reduced apoptosis during brain development. |
Goat Caspase 9 ELISA kit |
E06C0096-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A sandwich ELISA for quantitative measurement of Goat Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Caspase 9 ELISA kit |
E06C0096-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A sandwich ELISA for quantitative measurement of Goat Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Caspase 9 ELISA kit |
E06C0096-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A sandwich ELISA for quantitative measurement of Goat Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Caspase 9 Cell ELISA Kit |
abx595093-96tests |
Abbexa |
96 tests |
EUR 764.4 |
|
Human Caspase 9 ELISA kit |
55R-IB49680 |
Fitzgerald |
96 wells |
EUR 1413.6 |
Description: ELISA kit for the detection of Caspase 9 in the research laboratory |
Human Caspase 9 ELISA kit |
E01C0096-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A sandwich ELISA for quantitative measurement of Human Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Caspase 9 ELISA kit |
E01C0096-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A sandwich ELISA for quantitative measurement of Human Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Caspase 9 ELISA kit |
E01C0096-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A sandwich ELISA for quantitative measurement of Human Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Caspase 9 ELISA kit |
E03C0096-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A sandwich ELISA for quantitative measurement of Mouse Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Caspase 9 ELISA kit |
E03C0096-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A sandwich ELISA for quantitative measurement of Mouse Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Caspase 9 ELISA kit |
E03C0096-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A sandwich ELISA for quantitative measurement of Mouse Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Caspase 9 Assay Kit, green |
KF17206 |
Neuromics |
25 Tests |
EUR 364.8 |
Caspase-9 Colorimetric Assay Kit |
K119-100 |
Biovision |
each |
EUR 588 |
Caspase-9 Colorimetric Assay Kit |
K119-200 |
Biovision |
each |
EUR 744 |
Caspase-9 Colorimetric Assay Kit |
K119-25 |
Biovision |
each |
EUR 261.6 |
Caspase-9 Colorimetric Assay Kit |
K119-400 |
Biovision |
each |
EUR 1149.6 |
Caspase-9 Fluorometric Assay Kit |
K118-100 |
Biovision |
each |
EUR 561.6 |
Caspase-9 Fluorometric Assay Kit |
K118-200 |
Biovision |
each |
EUR 738 |
Caspase-9 Fluorometric Assay Kit |
K118-25 |
Biovision |
each |
EUR 248.4 |
Caspase-9 Fluorometric Assay Kit |
K118-400 |
Biovision |
each |
EUR 1149.6 |
Caspase-9 Fluorometric Assay Kit |
K2018-100 |
ApexBio |
100 assays |
EUR 602.4 |
Caspase-9 Fluorometric Assay Kit |
K2018-200 |
ApexBio |
200 assays |
EUR 802.8 |
Caspase-9 Fluorometric Assay Kit |
K2018-25 |
ApexBio |
25 assays |
EUR 285.6 |
Caspase-9 Fluorometric Assay Kit |
K2018-400 |
ApexBio |
400 assays |
EUR 1336.8 |
Caspase-9 Colorimetric Assay Kit |
K2019-100 |
ApexBio |
100 assays |
EUR 634.8 |
Caspase-9 Colorimetric Assay Kit |
K2019-200 |
ApexBio |
200 assays |
EUR 835.2 |
Caspase-9 Colorimetric Assay Kit |
K2019-25 |
ApexBio |
25 assays |
EUR 301.2 |
Caspase-9 Colorimetric Assay Kit |
K2019-400 |
ApexBio |
400 assays |
EUR 1387.2 |
Rabbit Caspase 9 ELISA kit |
E04C0096-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A sandwich ELISA for quantitative measurement of Rabbit Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Caspase 9 ELISA kit |
E04C0096-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A sandwich ELISA for quantitative measurement of Rabbit Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Caspase 9 ELISA kit |
E04C0096-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A sandwich ELISA for quantitative measurement of Rabbit Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Caspase 9 ELISA kit |
E09C0096-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A sandwich ELISA for quantitative measurement of Monkey Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Caspase 9 ELISA kit |
E09C0096-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A sandwich ELISA for quantitative measurement of Monkey Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Caspase 9 ELISA kit |
E09C0096-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A sandwich ELISA for quantitative measurement of Monkey Caspase 9 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Caspase 9 protein |
30R-2406 |
Fitzgerald |
25 units |
EUR 450 |
Description: Purified recombinant Human Caspase 9 protein |
Caspase 9 protein |
30R-2407 |
Fitzgerald |
50 ug |
EUR 697.2 |
Description: Purified recombinant Human Caspase 9 protein |
Mouse CASP9(Caspase-9) ELISA Kit |
EM0901 |
FN Test |
96T |
EUR 628.92 |
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml |
Human CASP9/ Caspase-9 ELISA Kit |
E0363Hu |
Sunlong |
1 Kit |
EUR 675.6 |
Human CASP9(Caspase-9) ELISA Kit |
EH0650 |
FN Test |
96T |
EUR 628.92 |
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml |
CLIA kit for Human CASP 9 (Caspase 9) |
E-CL-H0504 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 700.8 |
|
Description: A sandwich CLIA kit for quantitative measurement of Human CASP 9 (Caspase 9) in samples from Serum, Plasma, Cell supernatant |
Caspase 9 antibody |
70R-11636 |
Fitzgerald |
100 ug |
EUR 501.6 |
Description: Rabbit polyclonal Caspase 9 antibody |
Caspase 9 antibody |
70R-11806 |
Fitzgerald |
100 ug |
EUR 483.6 |
Description: Rabbit polyclonal Caspase 9 antibody |
Caspase 9 antibody |
70R-13511 |
Fitzgerald |
100 ul |
EUR 548.4 |
Description: Affinity purified Rabbit polyclonal Caspase 9 antibody |
Caspase 9 antibody |
70R-14132 |
Fitzgerald |
100 ug |
EUR 386.4 |
Description: Affinity purified Rabbit polyclonal Caspase 9 antibody |
Caspase 9 antibody |
70R-30659 |
Fitzgerald |
100 ug |
EUR 392.4 |
Description: Rabbit polyclonal Caspase 9 antibody |
Caspase 9 Antibody |
21422-100ul |
SAB |
100ul |
EUR 302.4 |
Caspase 9 Antibody |
21422-50ul |
SAB |
50ul |
EUR 224.4 |
UNASSIGNED
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