Cardiomyocyte irritation adopted by apoptosis and fibrosis is a crucial mediator for growth and development of coronary heart failure. Activation of toll-like receptor 4 (TLR4), an necessary regulator of irritation, causes the development of cardiac hypertrophy and harm. Nevertheless, the exact mechanism of TLR4-mediated antagonistic cardiac outcomes remains to be elusive. The current research was designed to seek out the function of TLR4 in cardiac fibrosis and apoptosis, and molecular mechanism thereof. Rats have been handled with TLR4 agonist (LPS 12.5 μg/kg/day) via osmotic pump for <em>14</em> days. To simulate the situation in vitro, H9c2 cells have been handled with LPS (1 μg/ml). Equally, H9c2 cells have been transfected with TLR4 and SIRT2 c-DNA clone for overexpression. Myocardial oxidative stress, irritation, fibrosis and mitochondrial parameters have been evaluated each in vitro and in vivo. Cardiac irritation after LPS therapy was confirmed by elevated TNF-α and IL-6 expression in rat coronary heart.
There was a marked improve in oxidative stress as noticed by elevated TBARS and decreased endogenous antioxidants (GSH and catalase), together with mitochondrial dysfunction as measured by mitochondrial complicated exercise in LPS-treated rat hearts. Histopathological examination confirmed the presence of cardiac fibrosis after LPS therapy. Protein expression of nuclear p53 and cleaved <em>caspase</em>-7/<em>caspase</em>-9 was considerably elevated in LPS handled coronary heart. Just like in vivo research, nuclear translocation of p53, mitochondrial dysfunction and mobile apoptosis have been noticed in H9c2 cells handled with LPS. Our knowledge additionally point out that decreased expression of SIRT2 was related to elevated acetylation of p53 after LPS therapy. In conclusion, TLR4 activation in rats promotes cardiac irritation, mitochondrial dysfunction, apoptosis and fibrosis. p53 and <em>caspase</em> 7/<em>caspase</em> 9 have been discovered to play an necessary function in TLR4-mediated apoptosis.
Our knowledge counsel that, lowering TLR4 mediated fibrosis and apoptosis may very well be a novel method within the therapy of coronary heart failure, retaining within the view the main function performed by TLR4 in cardiac irritation. BACKGROUND Cardiac distant ischemic conditioning (RIC) is a noninvasive cardioprotective methodology in ischemia-reperfusion harm and acute myocardial infarction (AMI). The goals of this research have been to analyze the results of RIC in a rat mannequin of AMI. MATERIAL AND METHODS Grownup male Sprague-Dawley rats included the AMI group that underwent ligation of the left anterior descending (LAD) coronary artery (n=24), the RIC group that consisted the AMI rat mannequin handled with RIC as soon as each day within the left hind limb till days 1, 7 and <em>14</em> (n=24), and the sham group (n=24). Myocardial infarct measurement was measured by routine histology with triphenyltetrazolium chloride (TTC) and Masson’s trichrome histochemical staining for myocardial necrosis and fibrosis, respectively.
Mitochondrial defect in muscle precedes neuromuscular junction degeneration and motor neuron dying in CHCHD10S59L/+ mouse.
Lately, we offered genetic foundation exhibiting that mitochondrial dysfunction can set off motor neuron degeneration, via identification of CHCHD10 encoding a mitochondrial protein. We reported sufferers, carrying the p.Ser59Leu heterozygous mutation in CHCHD10, from a big household with a mitochondrial myopathy related to motor neuron illness (MND). Quickly, our group and others reported CHCHD10 mutations in amyotrophic lateral sclerosis (ALS), frontotemporal dementia-ALS and different neurodegenerative illnesses. Right here, we generated knock-in (KI) mice, carrying the p.Ser59Leu mutation, that mimic the mitochondrial myopathy with mtDNA instability displayed by the sufferers from our authentic household. Earlier than months of age, all KI mice developed a deadly mitochondrial cardiomyopathy related to enhanced mitophagy.
mice additionally displayed neuromuscular junction (NMJ) and motor neuron degeneration with hyper-fragmentation of the motor finish plate and average however vital motor neuron loss in lumbar spinal twine on the finish stage of the illness. At this stage, we noticed TDP-43 cytoplasmic aggregates in spinal neurons. We additionally confirmed that motor neurons differentiated from human iPSC carrying the p.Ser59Leu mutation have been way more delicate to Staurosporine or glutamate-induced <em>caspase</em> activation than management cells. These knowledge verify that mitochondrial deficiency related to CHCHD10 mutations may be on the origin of MND. CHCHD10 is extremely expressed within the NMJ post-synaptic half. Importantly, the fragmentation of the motor finish plate was related to irregular CHCHD10 expression that was additionally noticed closed to NMJs which have been morphologically regular.
Moreover, we discovered OXPHOS deficiency in muscle of CHCHD10 mice at Three months of age within the absence of neuron loss in spinal twine. Our knowledge present that the pathological results of the p.Ser59Leu mutation goal muscle previous to NMJ and motor neurons. They seemingly result in OXPHOS deficiency, lack of cristae junctions and destabilization of inside membrane construction inside mitochondria at motor finish plate of NMJ, impairing neurotransmission. These knowledge are in favor with a key function for muscle in MND related to CHCHD10 mutations.
Activation of toll like receptor 4 (TLR4) promotes cardiomyocyte apoptosis through SIRT2 dependent p53 deacetylation
Manganese suppresses oxidative stress, irritation and caspase-Three activation in rats uncovered to chlorpyrifos.
The current research investigated the person and mixed impression of organophosphorus pesticide chlorpyrifos (CPF) and manganese (Mn), a naturally occurring hint steel, on hepatorenal perform in grownup rats. The 4 experimental teams particularly management, CPF alone (5 mg/kg), Mn alone (10 mg/kg) and the co-exposure group consisted of eight rats which have been orally gavage for <em>14</em> consecutive days. Following sacrifice, the biomarkers of hepatorenal injury, antioxidant enzyme actions, myeloperoxidase (MPO) exercise in addition to ranges of nitric oxide, reactive oxygen and nitrogen (RONS) species and lipid peroxidation (LPO) have been analysed spectrophotometrically.
Additional, the focus of tumour necrosis issue alpha (TNF-α), interleukin-1 β (IL-1β) and <em>caspase</em>-Three exercise have been assessed utilizing ELISA. Outcomes confirmed that the CPF-induced improve in biomarkers of hepatorenal toxicity have been considerably (p < 0.05) alleviated in rats co-expose to CPF and Mn. Furthermore, the lower in antioxidant standing in addition to the elevation in RONS and LPO have been considerably assuaged in rats co-treated with CPF and Mn. As well as, CPF mediated improve in TNF-α, IL-1β and <em>caspase</em>-Three exercise have been considerably diminished within the liver and kidney of rats co-exposed to CPF and Mn.
 anti- Caspase 10 antibody |
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FNab01285 |
FN Test |
100µg |
EUR 606.3 |
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Description: Antibody raised against Caspase 10 |
 anti- Caspase 12 antibody |
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FNab01286 |
FN Test |
100µg |
EUR 606.3 |
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Description: Antibody raised against Caspase 12 |
 anti- Caspase 2 antibody |
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FNab01287 |
FN Test |
100µg |
EUR 606.3 |
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Description: Antibody raised against Caspase 2 |
anti- Caspase 2 antibody |
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FNab01288 |
FN Test |
100µg |
EUR 658.5 |
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Description: Antibody raised against Caspase 2 |
 anti- Caspase 3 antibody |
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FNab01289 |
FN Test |
100µg |
EUR 606.3 |
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Description: Antibody raised against Caspase 3 |
 anti- Caspase 4 antibody |
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FNab01291 |
FN Test |
100µg |
EUR 606.3 |
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Description: Antibody raised against Caspase 4 |
 anti- Caspase 6 antibody |
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FNab01292 |
FN Test |
100µg |
EUR 658.5 |
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Description: Antibody raised against Caspase 6 |
 anti- Caspase 8 antibody |
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FNab01293 |
FN Test |
100µg |
EUR 606.3 |
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Description: Antibody raised against Caspase 8 |
anti- Caspase 8 antibody |
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FNab01294 |
FN Test |
100µg |
EUR 606.3 |
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Description: Antibody raised against Caspase 8 |
 anti- Caspase 9 antibody |
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FNab01295 |
FN Test |
100µg |
EUR 606.3 |
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Description: Antibody raised against Caspase 9 |
anti- Caspase 9 antibody |
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FNab01296 |
FN Test |
100µg |
EUR 606.3 |
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Description: Antibody raised against Caspase 9 |
anti- Caspase 9 antibody |
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FNab01297 |
FN Test |
100µg |
EUR 658.5 |
|
|
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Description: Antibody raised against Caspase 9 |
 ELISA kit) Rat Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
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E02C2800-48wellsplate |
BlueGene |
48 wells plate |
EUR 280 |
Rat Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
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E02C2800-96wellsplate |
BlueGene |
96 wells plate |
EUR 405 |
 Caspase 1 Antibody |
|
6687-100 |
Biovision |
each |
EUR 405.6 |
Caspase 1 Antibody |
|
6687-30T |
Biovision |
each |
EUR 175.2 |
 Caspase 1 antibody |
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70R-11561 |
Fitzgerald |
100 ug |
EUR 490 |
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Description: Rabbit polyclonal Caspase 1 antibody |
Caspase 1 antibody |
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70R-13979 |
Fitzgerald |
100 ug |
EUR 519 |
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Description: Affinity purified Rabbit polyclonal Caspase 1 antibody |
Caspase 1 antibody |
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70R-14061 |
Fitzgerald |
100 ug |
EUR 519 |
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Description: Affinity purified Rabbit polyclonal Caspase 1 antibody |
Caspase 1 antibody |
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70R-15367 |
Fitzgerald |
100 ug |
EUR 302 |
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Description: Rabbit polyclonal Caspase 1 antibody |
Caspase 1 antibody |
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70R-31086 |
Fitzgerald |
100 ug |
EUR 294 |
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Description: Rabbit polyclonal Caspase 1 antibody |
Caspase 1 antibody |
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70R-31087 |
Fitzgerald |
100 ug |
EUR 294 |
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Description: Rabbit polyclonal Caspase 1 antibody |
Caspase 1 antibody |
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70R-31116 |
Fitzgerald |
100 ug |
EUR 294 |
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Description: Rabbit polyclonal Caspase 1 antibody |
Caspase 1 antibody |
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70R-35920 |
Fitzgerald |
100 ug |
EUR 294 |
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Description: Rabbit polyclonal Caspase 1 antibody |
Caspase 1 antibody |
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70R-49451 |
Fitzgerald |
100 ul |
EUR 242 |
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Description: Purified Polyclonal Caspase 1 antibody |
Caspase 1 antibody |
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70R-49452 |
Fitzgerald |
100 ul |
EUR 242 |
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Description: Purified Polyclonal Caspase 1 antibody |
Caspase 1 antibody |
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70R-51474 |
Fitzgerald |
100 ul |
EUR 242 |
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Description: Purified Polyclonal Caspase 1 antibody |
Caspase 1 antibody |
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20R-1427 |
Fitzgerald |
100 ug |
EUR 781.2 |
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Description: Rabbit polyclonal Caspase 1 antibody |
 caspase 1 Antibody |
|
39310-100ul |
SAB |
100ul |
EUR 468 |
Caspase 1 Antibody |
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DF6148 |
Affbiotech |
200ul |
EUR 420 |
Caspase 1 Antibody |
|
DF6148-100ul |
Affinity Biosciences |
100ul |
EUR 168 |
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Description: WB,IHC,IF/ICC,ELISA(peptide) |
Caspase 1 Antibody |
|
DF6148-200ul |
Affinity Biosciences |
200ul |
EUR 210 |
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Description: WB,IHC,IF/ICC,ELISA(peptide) |
Caspase 1 Antibody |
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AF5418 |
Affbiotech |
200ul |
EUR 420 |
Caspase 1 Antibody |
|
AF5418-100ul |
Affinity Biosciences |
100ul |
EUR 168 |
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|
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Description: WB,IHC,IF/ICC,ELISA(peptide) |
Caspase 1 Antibody |
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AF5418-200ul |
Affinity Biosciences |
200ul |
EUR 210 |
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Description: WB,IHC,IF/ICC,ELISA(peptide) |
caspase 1 Antibody |
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E300022a |
EnoGene |
100ug/200ul |
EUR 275 |
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Description: Available in various conjugation types. |
caspase 1 Antibody |
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E300022b |
EnoGene |
200ul |
EUR 275 |
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Description: Available in various conjugation types. |
Caspase 1 Antibody |
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E38PA5426 |
EnoGene |
100ul |
EUR 225 |
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Description: Available in various conjugation types. |
Caspase 1 Antibody |
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E38PA1133 |
EnoGene |
100ul |
EUR 225 |
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Description: Available in various conjugation types. |
Caspase 1 Antibody |
|
E18-5418-1 |
EnoGene |
50μg/50μl |
EUR 145 |
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Description: Available in various conjugation types. |
Caspase 1 Antibody |
|
E18-5418-2 |
EnoGene |
100μg/100μl |
EUR 225 |
|
Description: Available in various conjugation types. |
Caspase 1 Antibody |
|
MBS5311125-01mg |
MyBiosource |
0.1mg |
EUR 640 |
Caspase 1 Antibody |
|
MBS5311125-5x01mg |
MyBiosource |
5x0.1mg |
EUR 2845 |
Caspase 1 Antibody |
|
MBS5312758-01mg |
MyBiosource |
0.1mg |
EUR 975 |
Caspase 1 Antibody |
|
MBS5312758-5x01mg |
MyBiosource |
5x0.1mg |
EUR 4245 |
Caspase 1 Antibody |
|
MBS5312832-01mg |
MyBiosource |
0.1mg |
EUR 975 |
Caspase 1 Antibody |
|
MBS5312832-5x01mg |
MyBiosource |
5x0.1mg |
EUR 4245 |
Caspase 1 Antibody |
|
MBS5316091-01mL |
MyBiosource |
0.1mL |
EUR 470 |
Caspase 1 Antibody |
|
MBS5316091-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1955 |
Caspase 1 Antibody |
|
MBS5314071-01mL |
MyBiosource |
0.1mL |
EUR 470 |
Caspase 1 Antibody |
|
MBS5314071-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1955 |
Caspase 1 Antibody |
|
MBS5314072-01mL |
MyBiosource |
0.1mL |
EUR 470 |
Caspase 1 Antibody |
|
MBS5314072-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1955 |
Caspase 1 Antibody |
|
MBS854390-01mLAF405L |
MyBiosource |
0.1mL(AF405L) |
EUR 565 |
Caspase 1 Antibody |
|
MBS854390-01mLAF405S |
MyBiosource |
0.1mL(AF405S) |
EUR 565 |
Caspase 1 Antibody |
|
MBS854390-01mLAF610 |
MyBiosource |
0.1mL(AF610) |
EUR 565 |
Caspase 1 Antibody |
|
MBS854390-01mLAF635 |
MyBiosource |
0.1mL(AF635) |
EUR 565 |
Caspase 1 Antibody |
|
MBS854390-02mL |
MyBiosource |
0.2mL |
EUR 345 |
Caspase 1 Antibody |
|
MBS8512045-005mg |
MyBiosource |
0.05mg |
EUR 235 |
Caspase 1 Antibody |
|
MBS8512045-01mg |
MyBiosource |
0.1mg |
EUR 305 |
Caspase 1 Antibody |
|
MBS8512045-01mLAF405M |
MyBiosource |
0.1mL(AF405M) |
EUR 465 |
Caspase 1 Antibody |
|
MBS8512045-01mLAF546 |
MyBiosource |
0.1mL(AF546) |
EUR 465 |
Caspase 1 Antibody |
|
MBS8512045-01mLAF750 |
MyBiosource |
0.1mL(AF750) |
EUR 465 |
Caspase 1 Antibody |
|
MBS852505-01mg |
MyBiosource |
0.1mg |
EUR 345 |
Caspase 1 Antibody |
|
MBS852505-01mLAF405L |
MyBiosource |
0.1mL(AF405L) |
EUR 565 |
Caspase 1 Antibody |
|
MBS852505-01mLAF405S |
MyBiosource |
0.1mL(AF405S) |
EUR 565 |
Caspase 1 Antibody |
|
MBS852505-01mLAF610 |
MyBiosource |
0.1mL(AF610) |
EUR 565 |
Caspase 1 Antibody |
|
MBS852505-01mLAF635 |
MyBiosource |
0.1mL(AF635) |
EUR 565 |
caspase 1 Antibody |
|
MBS9405204-01mL |
MyBiosource |
0.1mL |
EUR 420 |
caspase 1 Antibody |
|
MBS9405204-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1740 |
Caspase 1 Antibody |
|
MBS9204815-01mL |
MyBiosource |
0.1mL |
EUR 425 |
Caspase 1 Antibody |
|
MBS9204815-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1887 |
Caspase 1 Antibody |
|
MBS9214830-01mL |
MyBiosource |
0.1mL |
EUR 415 |
Caspase 1 Antibody |
|
MBS9214830-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1841 |
Caspase 1 Antibody |
|
MBS9232497-01mL |
MyBiosource |
0.1mL |
EUR 415 |
Caspase 1 Antibody |
|
MBS9232497-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1841 |
Caspase 1 Antibody |
|
MBS8580370-01mL |
MyBiosource |
0.1mL |
EUR 305 |
Caspase 1 Antibody |
|
MBS8580370-01mLAF405L |
MyBiosource |
0.1mL(AF405L) |
EUR 465 |
Caspase 1 Antibody |
|
MBS8580370-01mLAF405S |
MyBiosource |
0.1mL(AF405S) |
EUR 465 |
Caspase 1 Antibody |
|
MBS8580370-01mLAF610 |
MyBiosource |
0.1mL(AF610) |
EUR 465 |
Caspase 1 Antibody |
|
MBS8580370-01mLAF635 |
MyBiosource |
0.1mL(AF635) |
EUR 465 |
Caspase 1 Antibody |
|
MBS8583125-01mL |
MyBiosource |
0.1mL |
EUR 305 |
Caspase 1 Antibody |
|
MBS8583125-01mLAF405L |
MyBiosource |
0.1mL(AF405L) |
EUR 465 |
Caspase 1 Antibody |
|
MBS8583125-01mLAF405S |
MyBiosource |
0.1mL(AF405S) |
EUR 465 |
Caspase 1 Antibody |
|
MBS8583125-01mLAF610 |
MyBiosource |
0.1mL(AF610) |
EUR 465 |
Caspase 1 Antibody |
|
MBS8583125-01mLAF635 |
MyBiosource |
0.1mL(AF635) |
EUR 465 |
Caspase 1 Antibody |
|
MBS9601589-01mL |
MyBiosource |
0.1mL |
EUR 260 |
Caspase 1 Antibody |
|
MBS9601589-02mL |
MyBiosource |
0.2mL |
EUR 305 |
Caspase 1 Antibody |
|
MBS9601589-5x02mL |
MyBiosource |
5x0.2mL |
EUR 1220 |
Caspase 1 Antibody |
|
MBS9503923-005mL |
MyBiosource |
0.05mL |
EUR 285 |
Caspase 1 Antibody |
|
MBS9503923-01mL |
MyBiosource |
0.1mL |
EUR 385 |
Caspase 1 Antibody |
|
MBS9503923-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1590 |
 ELISA kit) Goat Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E06C2800-48wellsplate |
BlueGene |
48 wells plate |
EUR 280 |
Goat Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E06C2800-96wellsplate |
BlueGene |
96 wells plate |
EUR 405 |
 ELISA kit) Fish Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E17C2800-48wellsplate |
BlueGene |
48 wells plate |
EUR 280 |
Fish Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E17C2800-96wellsplate |
BlueGene |
96 wells plate |
EUR 405 |
 ELISA kit) Mouse Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E03C2800-48wellsplate |
BlueGene |
48 wells plate |
EUR 280 |
Mouse Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E03C2800-96wellsplate |
BlueGene |
96 wells plate |
EUR 405 |
 ELISA kit) Human Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E01C2800-48wellsplate |
BlueGene |
48 wells plate |
EUR 280 |
Human Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E01C2800-96wellsplate |
BlueGene |
96 wells plate |
EUR 405 |
 ELISA kit) Sheep Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E14C2800-48wellsplate |
BlueGene |
48 wells plate |
EUR 280 |
Sheep Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E14C2800-96wellsplate |
BlueGene |
96 wells plate |
EUR 405 |
 Caspase-1 Antibody |
|
48847-100ul |
SAB |
100ul |
EUR 399.6 |
Caspase-1 Antibody |
|
48847-50ul |
SAB |
50ul |
EUR 286.8 |
Caspase-1 Antibody |
|
3459-002mg |
ProSci |
0.02 mg |
EUR 206.18 |
|
|
|
Description: Caspase-1 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1β and IL-18. Caspase-1 was initially identified as an IL-1β-converting enzyme; later experiments revealed it to be a mammalian homolog of the C. elegans cell death gene ced-3 whose overexpression can induce apoptosis in fibroblasts. |
Caspase-1 Antibody |
|
3459-01mg |
ProSci |
0.1 mg |
EUR 523.7 |
|
|
|
Description: Caspase-1 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1β and IL-18. Caspase-1 was initially identified as an IL-1β-converting enzyme; later experiments revealed it to be a mammalian homolog of the C. elegans cell death gene ced-3 whose overexpression can induce apoptosis in fibroblasts. |
Caspase-1 Antibody |
|
3463-002mg |
ProSci |
0.02 mg |
EUR 206.18 |
|
|
|
Description: Caspase-1 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1β and IL-18. Caspase-1 was initially identified as an IL-1β-converting enzyme; later experiments revealed it to be a mammalian homolog of the C. elegans cell death gene ced-3 whose overexpression can induce apoptosis in fibroblasts. |
Caspase-1 Antibody |
|
3463-01mg |
ProSci |
0.1 mg |
EUR 523.7 |
|
|
|
Description: Caspase-1 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1β and IL-18. Caspase-1 was initially identified as an IL-1β-converting enzyme; later experiments revealed it to be a mammalian homolog of the C. elegans cell death gene ced-3 whose overexpression can induce apoptosis in fibroblasts. |
Caspase-1 Antibody |
|
3019-100 |
Biovision |
each |
EUR 483.6 |
Caspase-1 Antibody |
|
3019-30T |
Biovision |
each |
EUR 175.2 |
Caspase-1 Antibody |
|
24290-100ul |
SAB |
100ul |
EUR 468 |
Caspase-1 Antibody |
|
24291-100ul |
SAB |
100ul |
EUR 468 |
Caspase-1 Antibody |
|
C30122-100ul |
Assay Biotech |
100μl |
EUR 217 |
|
Description: Caspase-1 Rabbit Polyclonal Antibody |
Caspase-1 Antibody |
|
C30122-50ul |
Assay Biotech |
50μl |
EUR 143.5 |
|
Description: Caspase-1 Rabbit Polyclonal Antibody |
Caspase-1 Antibody |
|
B1025-100ul |
Assay Biotech |
100μl |
EUR 217 |
|
Description: Caspase-1 Rabbit Polyclonal Antibody |
Caspase-1 Antibody |
|
B1025-50ul |
Assay Biotech |
50μl |
EUR 143.5 |
|
Description: Caspase-1 Rabbit Polyclonal Antibody |
Caspase-1 Antibody |
|
MBS150194-01mg |
MyBiosource |
0.1mg |
EUR 445 |
Caspase-1 Antibody |
|
MBS150194-5x01mg |
MyBiosource |
5x0.1mg |
EUR 1965 |
Caspase-1 Antibody |
|
MBS151296-01mg |
MyBiosource |
0.1mg |
EUR 445 |
Caspase-1 Antibody |
|
MBS151296-5x01mg |
MyBiosource |
5x0.1mg |
EUR 1965 |
Caspase-1 Antibody |
|
MBS9411447-01mL |
MyBiosource |
0.1mL |
EUR 495 |
Caspase-1 Antibody |
|
MBS9411447-5x01mL |
MyBiosource |
5x0.1mL |
EUR 2075 |
Caspase-1 Antibody |
|
MBS9435665-005mL |
MyBiosource |
0.05mL |
EUR 325 |
Caspase-1 Antibody |
|
MBS9435665-01mL |
MyBiosource |
0.1mL |
EUR 435 |
Caspase-1 Antibody |
|
MBS9435665-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1810 |
Caspase-1 Antibody |
|
MBS9413626-01mL |
MyBiosource |
0.1mL |
EUR 495 |
Caspase-1 Antibody |
|
MBS9413626-5x01mL |
MyBiosource |
5x0.1mL |
EUR 2075 |
 ELISA kit) Rabbit Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E04C2800-48wellsplate |
BlueGene |
48 wells plate |
EUR 280 |
Rabbit Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E04C2800-96wellsplate |
BlueGene |
96 wells plate |
EUR 405 |
 ELISA kit) Canine Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E08C2800-48wellsplate |
BlueGene |
48 wells plate |
EUR 280 |
Canine Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E08C2800-96wellsplate |
BlueGene |
96 wells plate |
EUR 405 |
 ELISA kit) Monkey Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E09C2800-48wellsplate |
BlueGene |
48 wells plate |
EUR 280 |
Monkey Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E09C2800-96wellsplate |
BlueGene |
96 wells plate |
EUR 405 |
 ELISA kit) Bovine Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E11C2800-48wellsplate |
BlueGene |
48 wells plate |
EUR 280 |
Bovine Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E11C2800-96wellsplate |
BlueGene |
96 wells plate |
EUR 405 |
 ELISA kit) Porcine Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E07C2800-48wellsplate |
BlueGene |
48 wells plate |
EUR 280 |
Porcine Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E07C2800-96wellsplate |
BlueGene |
96 wells plate |
EUR 405 |
 ELISA kit) Chicken Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E12C2800-48wellsplate |
BlueGene |
48 wells plate |
EUR 280 |
Chicken Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E12C2800-96wellsplate |
BlueGene |
96 wells plate |
EUR 405 |
 ELISA kit) Hamster Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E18C2800-48wellsplate |
BlueGene |
48 wells plate |
EUR 280 |
Hamster Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E18C2800-96wellsplate |
BlueGene |
96 wells plate |
EUR 405 |
 ELISA kit) Guinea Pig Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E05C2800-48wellsplate |
BlueGene |
48 wells plate |
EUR 280 |
Guinea Pig Anti Caspase 1 antibody (Anti Casp 1) ELISA kit |
|
E05C2800-96wellsplate |
BlueGene |
96 wells plate |
EUR 405 |
) Caspase 1 antibody (HRP) |
|
60R-1915 |
Fitzgerald |
100 ug |
EUR 302 |
|
|
|
Description: Rabbit polyclonal Caspase 1 antibody (HRP) |
) Caspase 1 antibody (FITC) |
|
60R-1916 |
Fitzgerald |
100 ug |
EUR 302 |
|
|
|
Description: Rabbit polyclonal Caspase 1 antibody (FITC) |
 Rabbit anti Caspase 1 Polyclonal Antibody |
|
MBS460196-01mg |
MyBiosource |
0.1mg |
EUR 320 |
Rabbit anti Caspase 1 Polyclonal Antibody |
|
MBS460196-5x01mg |
MyBiosource |
5x0.1mg |
EUR 1390 |
 Anti-active Caspase 3 Antibody |
|
MBS9241147-01mL |
MyBiosource |
0.1mL |
EUR 415 |
Anti-active Caspase 3 Antibody |
|
MBS9241147-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1841 |
 Antibody) Caspase 12 (Caspase 12) Antibody |
|
20-abx007974 |
Abbexa |
-
Ask for price
-
Ask for price
-
Ask for price
|
|
|
|
Caspase 12 (Caspase 12) Antibody |
|
abx231286-100ug |
Abbexa |
100 ug |
EUR 577.2 |
|
|
Caspase 12 (Caspase 12) Antibody |
|
abx432451-200ul |
Abbexa |
200 ul |
EUR 460.8 |
|
|
 Polyclonal Anti- Caspase 4 Antibody |
|
GWB-BBP367 |
GenWay Biotech |
0.1 mg |
Ask for price |
) Caspase 1 antibody (Ser376) |
|
70R-35444 |
Fitzgerald |
100 ug |
EUR 294 |
|
|
|
Description: Purified Rabbit polyclonal Caspase 1 antibody (Ser376) |
Mild microscopic examination evidenced that the severity of histopathological lesions induced by CPF have been alleviated in rats co-exposed to CPF and Mn. In conclusion, the outcomes spotlight that co-exposure to CPF and Mn in rats assuaged CPF-induced oxidative stress, irritation and <em>caspase</em>-Three activation within the liver and kidney of the rats.
