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December 11, 2020

Protective effect of hesperidin against N,N’-dimethylhydrazine induced oxidative stress, inflammation, and apoptotic response in the colon of Wistar rats

Hesperidin (HD), a citrus bioflavonoid possesses quite a lot of organic actions together with antioxidant, anti-inflammatory, anti-apoptotic and anti-carcinogenic properties. Within the current examine, we investigated the impact of HD remedy on N,N’-dimethylhydrazine (DMH) induced oxidative stress, irritation, apoptosis and goblet cell disintegration within the colon of Wistar rats. Administration of HD was accomplished at two doses (100 and 200 mg/kg physique weight) orally to […]