December 11, 2020

Temporal Patterns of Blood Biomarker candidates of Cardiac Remodeling in Relation to Prognosis of Patients With Chronic Heart Failure-The Bio- SH i FT Study.

By Dylan

Background Transforming biomarkers carry excessive potential for predicting hostile occasions in persistent coronary heart failure ( CHF ) sufferers. Nonetheless, temporal patterns throughout the course of CHF , and particularly the trajectory earlier than an hostile occasion, are unknown. We studied the prognostic worth of temporal patterns of cardiac reworking biomarker candidates in steady sufferers with CHF from the Bio-SHiFT (Serial Biomarker Measurements and New Echocardiographic Methods in Persistent Coronary heart Failure Sufferers End in Tailor-made Prediction of Prognosis) research. Strategies and Outcomes In 263 CHF sufferers, we carried out trimonthly blood sampling throughout a median follow-up of two.2 years.

For the evaluation, we chosen all baseline samples, the two samples closest to the first finish level ( PE ), or the final pattern out there for finish point-free sufferers. Thus, in 567 samples, we measured suppression of tumorigenicity-2, galectin-3, galectin-4, progress differentiation factor-15, matrix metalloproteinase-2, 3, and 9, tissue inhibitor metalloproteinase-4, perlecan, aminopeptidase-N, <em>caspase</em>-3, cathepsin-D, cathepsin-Z, and cystatin-B. The PE was a composite of cardiovascular mortality, coronary heart transplantation, left ventricular help machine implantation, and HF hospitalization. Associations between repeatedly measured biomarker candidates and the PE had been investigated by joint modeling. Median age was 68 (interquartile vary: 59-76) years with 72% males; 70 sufferers reached the PE . Repeatedly measured suppression of tumorigenicity-2, galectin-3, galectin-4, progress differentiation factor-15, matrix metalloproteinase-2 and 9, tissue inhibitor metalloproteinase-4, perlecan, cathepsin-D, and cystatin-B ranges had been considerably related to the PE , and elevated because the PE approached. The slopes of biomarker trajectories had been additionally predictors of scientific end result, impartial of their absolute stage. Associations continued after adjustment for scientific traits and pharmacological therapy.

Suppression of tumorigenicity-2 was the strongest predictor (hazard ratio: 7.55 per SD distinction, 95% CI : 5.53-10.30), adopted by progress differentiation factor-15 and matrix metalloproteinase-2. Conclusions Temporal patterns of reworking biomarker candidates predict hostile scientific outcomes in CHF. JNK and its downstream transcriptional elements together with c-Jun, activating transcription issue 2 (ATF2), and JunD had been all considerably phosphorylated in CIH rats. Nonetheless, pretreatment of NF-κB inhibitor BAY 11-7082 inhibited the activation of NF-κB below CIH situation and likewise considerably decreased the phosphorylation of JNK in addition to c-Jun, ATF2, and JunD.

 

Novel compound VB-037 inhibits Aβ aggregation and promotes neurite outgrowth via enhancement of HSP27 and discount of P38 and JNK-mediated irritation in cell fashions for Alzheimer’s illness.

The pathogenesis of Alzheimer’s illness (AD) is concerned within the aggregation of misfolded amyloid β (Aβ), which upregulates the exercise of acetylcholinesterase (AChE), will increase the manufacturing of reactive oxygen species (ROS), enhances neuroinflammation, and finally results in neuronal dying. Due to this fact, compounds concentrating on these mechanisms could also be candidates for multitarget medication in AD therapy. We discovered that two quinoline derivatives, VB-030 and VB-037, markedly decreased Aβ aggregation and ROS ranges within the thioflavin T biochemical assay and Tet-On Aβ-green fluorescent protein (GFP) 293 AD cell mannequin. These compounds additional improved neurite outgrowth, decreased AChE exercise and upregulated the molecular chaperone warmth shock protein household B [small] member 1 (HSP27), whereas knockdown of HSP27 counteracted the compounds’ neuroprotective results on the Tet-On neuronal mannequin. Moreover, VB-037 attenuated lipopolysaccharide (LPS)/interferon (IFN)-γ-induced activation of BV-2 microglial cells.
As well as, VB-037 demonstrated its potential to decrease LPS/IFN-γ-induced upregulation of <em>caspase</em> 1 exercise, expression of interleukin (IL)-1β, and lively phosphorylation of mitogen-activated protein kinase <em>14</em> (P38), mitogen-activated protein kinase 8 (JNK), and Jun proto-oncogene, AP-1 transcription issue subunit (JUN) signalings, in addition to enhance cell viability within the Tet-On neuronal mannequin. Our findings strongly point out the potential of VB-037 for modifying AD development by concentrating on a number of mechanisms, thereby providing a brand new drug improvement avenue for AD therapy. Hepatitis B virus X (HBx), a viral onco-protein encoded by HBV, can promote oncogenesis of HCC. Nonetheless, the mechanism of HBx in hepatocarcinogenesis remains to be unclear. On this research, we set up a brand new mouse mannequin with regular immune system to analyze the position of HBx and its purposeful mechanisms below regular immune operate.
The animal mannequin was established by injecting HBx-EGFP-<em>14</em>-19 cells into the hepatic portal vein of KM mice. To confirm the mouse mannequin, the expression of HBx within the liver tissue of mice was detected by qRT-PCR, western blotting and immunohistochemistry. The apoptosis index was calculated utilizing the terminal deoxynucleotidyl transferase-dUTP nick-end labeling (TUNEL) assay, and the expression ranges of apoptosis-related and cell cycle-related elements had been measured.

Metformin alleviates hyperglycemia-induced endothelial impairment by downregulating autophagy by way of the Hedgehog pathway.

Research relating to macroautophagic/autophagic regulation in endothelial cells (ECs) below diabetic circumstances are very restricted. Medical proof establishes an endothelial protecting impact of metformin, however the underlying mechanisms stay unclear. We aimed to analyze whether or not metformin exerts its protecting position in opposition to hyperglycemia-induced endothelial impairment via the autophagy equipment. db/db mice had been handled with intravitreal metformin injections. Human umbilical vein endothelial cells (HUVECs) had been cultured both in regular glucose (NG, 5.5 mM) or excessive glucose (HG, 33 mM) medium within the presence or absence of metformin for 72 h. We noticed an apparent inhibition of hyperglycemia-triggered autophagosome synthesis in each the diabetic retinal vasculature and cultured HUVECs by metformin, together with restoration of hyperglycemia-impaired Hedgehog (Hh) pathway exercise.
Particularly, deletion of ATG7 in retinal vascular ECs of db/db mice and cultured HUVECs indicated a detrimental position of autophagy in hyperglycemia-induced endothelial dysfunction. Pretreatment with GANT61, a Hh pathway inhibitor, abolished the metformin-mediated downregulation of autophagy and endothelial protecting motion. Moreover, GLI-family (transcription elements of the Hh pathway) knockdown in HUVECs and retinal vasculature revealed that downregulation of hyperglycemia-activated autophagy by the metformin-mediated Hh pathway activation was GLI1 dependent. Mechanistically, GLI1 knockdown-triggered autophagy was associated to upregulation of BNIP3, which subsequently disrupted the affiliation of BECN1/Beclin 1 and BCL2.
Anti-Caspase 12 antibody
PAab01286 100 ug
EUR 355
Caspase 12 (Caspase 12) Antibody
20-abx007974
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  • 100 ul
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Caspase 12 (Caspase 12) Antibody
abx432451-200ul 200 ul
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Caspase 12 (Caspase 12) Antibody
abx231286-100ug 100 ug
EUR 481
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Anti-Caspase-12/CASP12 Antibody
PA2103 100ug/vial
EUR 334
Caspase-12 Antibody
24119-100ul 100ul
EUR 390
Caspase-12 Antibody
24120-100ul 100ul
EUR 390
Caspase 12 antibody
20R-1513 100 ug
EUR 673
Description: Rabbit polyclonal Caspase 12 antibody
Caspase 12 antibody
70R-11740 100 ug
EUR 460
Description: Rabbit polyclonal Caspase 12 antibody
Caspase-12 Antibody
3282-100
EUR 354
Caspase-12 Antibody
3282-30T
EUR 146
Caspase 12 antibody
70R-51166 100 ul
EUR 244
Description: Purified Polyclonal Caspase 12 antibody
Anti-Caspase 12 (aa232-244) antibody
STJ72856 100 µg
EUR 359
Caspase-12
RA15048 100 ug
EUR 461
Human cysteinyl aspartate specific proteinases 12,Caspase-12 ELISA Kit
201-12-0763 96 tests
EUR 440
  • This cysteinyl aspartate specific proteinases 12 ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.
Rabbit Polyclonal antibody Anti-CRBN
Anti-CRBN 50 µg
EUR 349
Caspase-12 Antibody (Large)
24208-100ul 100ul
EUR 390
Caspase-12 Antibody (Small)
24209-100ul 100ul
EUR 390
Polyclonal Caspase-12 Antibody
APR00058G 0.1mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-12 . This antibody is tested and proven to work in the following applications:
Caspase 12 (CASP12) Antibody
abx026563-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.
Caspase 12 (CASP12) Antibody
abx026563-80l 80 µl
EUR 286
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Caspase 12 (CASP12) Antibody
abx216233-100ug 100 ug
EUR 439
  • Shipped within 5-10 working days.
Caspase 12 (CASP12) Antibody
20-abx213378
  • EUR 411.00
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  • 100 ul
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Caspase 12 (CASP12) Antibody
20-abx210324
  • EUR 411.00
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Caspase 12 (CASP12) Antibody
20-abx100899
  • EUR 425.00
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  • 100 ug
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Caspase 12 (CASP12) Antibody
20-abx111421
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Caspase 12 (CASP12) Antibody
20-abx129818
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  • 100 ug
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  • 200 ug
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Polyclonal Caspase-12 Antibody
APR06275G 0.1 mg
EUR 659
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-12 . This antibody is tested and proven to work in the following applications:
Polyclonal Caspase-12 Antibody
APR06276G 0.1 mg
EUR 659
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-12 . This antibody is tested and proven to work in the following applications:
Caspase 12 (Casp12) Antibody
20-abx318989
  • EUR 411.00
  • EUR 1845.00
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  • 100 ug
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  • Shipped within 5-10 working days.
Caspase 12 (CASP12) Antibody
20-abx324638
  • EUR 314.00
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  • 100 ug
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Caspase 12 (CASP12) Antibody
20-abx318255
  • EUR 411.00
  • EUR 1845.00
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.
Caspase 12 Polyclonal Antibody
ABP50853-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from the Internal region of human Caspase12
  • Applications tips:
Description: A polyclonal antibody for detection of Caspase 12 from Human. This Caspase 12 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Caspase12
Caspase 12 Polyclonal Antibody
ABP50853-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from the Internal region of human Caspase12
  • Applications tips:
Description: A polyclonal antibody for detection of Caspase 12 from Human. This Caspase 12 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Caspase12
Caspase 12 Polyclonal Antibody
ABP50853-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from the Internal region of human Caspase12
  • Applications tips:
Description: A polyclonal antibody for detection of Caspase 12 from Human. This Caspase 12 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Caspase12
Rabbit Anti Caspase-12 (Aa100-116) Polyclonal Antibody
CPBT-66303RC 0.1 mg
EUR 580
Polyclonal Caspase-12 Antibody (Large)
APR06327G 0.1 mg
EUR 659
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-12 (Large). This antibody is tested and proven to work in the following applications:
Polyclonal Caspase-12 Antibody (Small)
APR06328G 0.1 mg
EUR 659
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-12 (Small). This antibody is tested and proven to work in the following applications:
Caspase 12 (Casp12) Antibody (HRP)
20-abx318990
  • EUR 411.00
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.
Caspase 12 (Casp12) Antibody (FITC)
20-abx318991
  • EUR 411.00
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
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Caspase 12 (Casp12) Antibody (Biotin)
20-abx318992
  • EUR 411.00
  • EUR 1845.00
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  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.
Caspase 12 (CASP12) Antibody (HRP)
20-abx316303
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.
Caspase 12 (CASP12) Antibody (FITC)
20-abx316304
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.
Caspase 12 (CASP12) Antibody (Biotin)
20-abx316305
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.
Caspase 12 Blocking Peptide
33R-10465 50 ug
EUR 349
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of Caspase 12 antibody, catalog no. 20R-1513
Caspase 12 Blocking Peptide
33R-10701 50 ug
EUR 191
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of Caspase 12 antibody, catalog no. 70R-11740
Caspase-12 Blocking Peptide
3282BP-50
EUR 153
Caspase 12 Assay Kit
55R-1290 25 assays
EUR 328
Description: Assay Kit for detection of Capase 12 activity in the research laboratory
Caspase-12 Rabbit pAb
A0217-100ul 100 ul
EUR 308
Caspase-12 Rabbit pAb
A0217-200ul 200 ul
EUR 459
Caspase-12 Rabbit pAb
A0217-20ul 20 ul
EUR 183
Caspase-12 Rabbit pAb
A0217-50ul 50 ul
EUR 223
Caspase 12 Blocking Peptide
20-abx064041
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg
  • Shipped within 5-10 working days.
Recombinant Caspase 12 (CASP12)
4-RPA682Mu01
  • EUR 467.36
  • EUR 228.00
  • EUR 1477.60
  • EUR 559.20
  • EUR 1018.40
  • EUR 376.00
  • EUR 3544.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: O08736
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 79.6kDa
  • Isoelectric Point: 6.1
Description: Recombinant Mouse Caspase 12 expressed in: E.coli
Recombinant Caspase 12 (CASP12)
4-RPA682Ra01
  • EUR 494.24
  • EUR 235.00
  • EUR 1578.40
  • EUR 592.80
  • EUR 1085.60
  • EUR 394.00
  • EUR 3796.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q920D5
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 31.4kDa
  • Isoelectric Point: 5.1
Description: Recombinant Rat Caspase 12 expressed in: E.coli
99445-12 DCT 12 X 75MM
99445-12 250/pk
EUR 67
Description: Disposable Culture Tubes; DCT's, CGW
Caspase 12 (CASP12) Polyclonal Antibody (Mouse)
4-PAA682Mu01
  • EUR 236.00
  • EUR 2338.00
  • EUR 586.00
  • EUR 294.00
  • EUR 209.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Phe413)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Caspase 12 (CASP12)
Human Caspase 12,Casp-12 ELISA Kit
CN-03708H1 96T
EUR 486
Human Caspase 12,Casp-12 ELISA Kit
CN-03708H2 48T
EUR 336
Caspase-12 Substrate ATAD-AFC
1117-1000
EUR 1088
Caspase-12 Substrate ATAD-AFC
1117-200
EUR 436
Human Caspase 12 ELISA kit
E01C0690-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Human Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Caspase 12 ELISA kit
E01C0690-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Human Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Caspase 12 ELISA kit
E01C0690-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Human Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Caspase 12 ELISA kit
E06C0690-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Goat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Caspase 12 ELISA kit
E06C0690-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Goat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Caspase 12 ELISA kit
E06C0690-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Goat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Caspase 12 ELISA kit
E03C0690-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Mouse Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Caspase 12 ELISA kit
E03C0690-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Mouse Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Caspase 12 ELISA kit
E03C0690-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Mouse Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Caspase 12 ELISA kit
E04C0690-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rabbit Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Caspase 12 ELISA kit
E04C0690-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rabbit Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Caspase 12 ELISA kit
E04C0690-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Rabbit Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rat Caspase 12 ELISA kit
E02C0690-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rat Caspase 12 ELISA kit
E02C0690-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Rat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rat Caspase 12 ELISA kit
E02C0690-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Rat Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Caspase 12 (CASP12) Protein
20-abx167225
  • EUR 648.00
  • EUR 272.00
  • EUR 1998.00
  • EUR 773.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Rat Caspase 12 (CASP12) Protein
20-abx065753
  • EUR 690.00
  • EUR 286.00
  • EUR 2124.00
  • EUR 815.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Human Caspase-12 ELISA Kit
EHC0697 96Tests
EUR 521
Monkey Caspase 12 ELISA kit
E09C0690-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Monkey Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Monkey Caspase 12 ELISA kit
E09C0690-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Monkey Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Monkey Caspase 12 ELISA kit
E09C0690-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Monkey Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Caspase-12 ELISA Kit
EGTC0697 96Tests
EUR 521
Dog Caspase 12 ELISA kit
E08C0690-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Canine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Dog Caspase 12 ELISA kit
E08C0690-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Canine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Dog Caspase 12 ELISA kit
E08C0690-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Canine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Caspase 12 ELISA kit
E07C0690-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Porcine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Caspase 12 ELISA kit
E07C0690-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Porcine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Caspase 12 ELISA kit
E07C0690-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Porcine Caspase 12 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Bovine Caspase-12 ELISA Kit
EBC0697 96Tests
EUR 521
Canine Caspase-12 ELISA Kit
ECC0697 96Tests
EUR 521
Anserini Caspase-12 ELISA Kit
EAC0697 96Tests
EUR 521
Caspase 12 ELISA KIT|Human
EF008399 96 Tests
EUR 689
Mouse Caspase-12 ELISA Kit
EMC0697 96Tests
EUR 521
Rat Caspase-12 ELISA Kit
ERC0697 96Tests
EUR 521
Rabbit Caspase-12 ELISA Kit
ERTC0697 96Tests
EUR 521
Porcine Caspase-12 ELISA Kit
EPC0697 96Tests
EUR 521
Caspase-12 Fluorometric Assay Kit
K2150-100 100 assays
EUR 529
Caspase-12 Fluorometric Assay Kit
K2150-25 25 assays
EUR 251
Caspase-12 Fluorometric Assay Kit
K139-100
EUR 501
Caspase-12 Fluorometric Assay Kit
K139-25
EUR 256
Caspase 12 (CASP12) Polyclonal Antibody (Mouse), APC
4-PAA682Mu01-APC
  • EUR 329.00
  • EUR 3041.00
  • EUR 854.00
  • EUR 416.00
  • EUR 212.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Phe413)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Caspase 12 (CASP12). This antibody is labeled with APC.
Caspase 12 (CASP12) Polyclonal Antibody (Mouse), Biotinylated
4-PAA682Mu01-Biotin
  • EUR 299.00
  • EUR 2288.00
  • EUR 684.00
  • EUR 363.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Phe413)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Caspase 12 (CASP12). This antibody is labeled with Biotin.
Caspase 12 (CASP12) Polyclonal Antibody (Mouse), Cy3
4-PAA682Mu01-Cy3
  • EUR 397.00
  • EUR 4013.00
  • EUR 1097.00
  • EUR 513.00
  • EUR 241.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Phe413)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Caspase 12 (CASP12). This antibody is labeled with Cy3.
Caspase 12 (CASP12) Polyclonal Antibody (Mouse), FITC
4-PAA682Mu01-FITC
  • EUR 283.00
  • EUR 2452.00
  • EUR 703.00
  • EUR 353.00
  • EUR 189.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Phe413)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Caspase 12 (CASP12). This antibody is labeled with FITC.
Caspase 12 (CASP12) Polyclonal Antibody (Mouse), HRP
4-PAA682Mu01-HRP
  • EUR 302.00
  • EUR 2652.00
  • EUR 756.00
  • EUR 377.00
  • EUR 200.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Phe413)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Caspase 12 (CASP12). This antibody is labeled with HRP.
Caspase 12 (CASP12) Polyclonal Antibody (Mouse), PE
4-PAA682Mu01-PE
  • EUR 283.00
  • EUR 2452.00
  • EUR 703.00
  • EUR 353.00
  • EUR 189.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Phe413)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Caspase 12 (CASP12). This antibody is labeled with PE.
Caspase 12 (CASP12) Polyclonal Antibody (Mouse, Rat)
4-PAA682Ra01
  • EUR 243.00
  • EUR 2457.00
  • EUR 613.00
  • EUR 305.00
  • EUR 212.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CASP12 (Met1~Thr244)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Caspase 12 (CASP12)
Individual Reaction Mix 12
G065-12 200 reactions
EUR 167
Human 12-lipoxygenase,LOX-12 ELISA Kit
201-12-0949 96 tests
EUR 440
  • This 12-lipoxygenase ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.
Anti-Caspase-4 Antibody
A02941 100ul
EUR 397
Description: Rabbit Polyclonal Caspase-4 Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat.
Anti-Caspase-1 Antibody
A00048 100ug
EUR 432
Description: Rabbit Polyclonal Caspase-1 Antibody. Validated in IP, IF, IHC, WB and tested in Human, Mouse, Rat.
Anti-Caspase-3 Antibody
A1751-100
EUR 479
Anti-Caspase-7 Antibody
A1752-100
EUR 479
anti- Caspase 2 antibody
FNab098281 100µg
EUR 548.75
  • Recommended dilution: WB: 1:1000-1:6000
  • Immunogen: Caspase 2
  • Uniprot ID: P42575
  • Gene ID: 835
  • Research Area: Neuroscience, Immunology, Signal Transduction
Description: Antibody raised against Caspase 2
anti- Caspase 3 antibody
FNab10013 100µg
EUR 548.75
  • Recommended dilution: WB: 1:200-1:2000
  • IHC: 1:50-1:500
  • Immunogen: caspase 3, apoptosis-related cysteine peptidase
  • Uniprot ID: P42574
  • Research Area: Cancer, Metabolism, Neuroscience
Description: Antibody raised against Caspase 3
anti- Caspase 1 antibody
FNab10015 100µg
EUR 548.75
  • Recommended dilution: WB: 1:200-1:2000
  • IHC: 1:50-1:500
  • Immunogen: caspase 1
  • Uniprot ID: P29466
  • Gene ID: 834
  • Research Area: Signal Transduction, Metabolism, Cardiovascular, Neuroscience
Description: Antibody raised against Caspase 1
anti- Caspase 8 antibody
FNab10024 100µg
EUR 548.75
  • Recommended dilution: WB: 1:500-1:2000
  • IHC: 1:50-1:500
  • Immunogen: caspase 8, apoptosis-related cysteine peptidase
  • Uniprot ID: Q14790
  • Gene ID: 841
  • Research Area: Signal Transduction, Metabolism, cancer
Description: Antibody raised against Caspase 8
anti- Caspase 1 antibody
FNab01284 100µg
EUR 548.75
  • Recommended dilution: WB: 1:500-1:2000,IHC: 1:20-1:200
  • Immunogen: caspase 1, apoptosis-related cysteine peptidase(interleukin 1, beta, convertase)
  • Uniprot ID: P29466
  • Gene ID: 834
  • Research Area: Metabolism
Description: Antibody raised against Caspase 1
anti- Caspase 10 antibody
FNab01285 100µg
EUR 505.25
  • Recommended dilution: WB: 1:500-1:1000
  • IP: 1:200-1:1000
  • IHC: 1:20-1:200
  • IF: 1:20-1:200
  • Immunogen: caspase 10, apoptosis-related cysteine peptidase
  • Uniprot ID: Q92851
  • Gene ID: 843
  • Research Area: Metabolism
Description: Antibody raised against Caspase 10
anti- Caspase 2 antibody
FNab01287 100µg
EUR 505.25
  • Recommended dilution: WB: 1:500-1:2000
  • IHC: 1:50-1:200
  • Immunogen: caspase 2, apoptosis-related cysteine peptidase
  • Uniprot ID: P42575
  • Research Area: Metabolism
Description: Antibody raised against Caspase 2
anti- Caspase 2 antibody
FNab01288 100µg
EUR 548.75
  • Recommended dilution: WB: 1:500-1:2000
  • IHC: 1:50-1:200
  • Immunogen: caspase 2, apoptosis-related cysteine peptidase
  • Uniprot ID: P42575
  • Research Area: Metabolism
Description: Antibody raised against Caspase 2
anti- Caspase 3 antibody
FNab01289 100µg
EUR 505.25
  • Recommended dilution: WB: 1:200-1:2000
  • IP: 1:200-1:2000
  • IHC: 1:50-1:500
  • IF: 1:20-1:200
  • Immunogen: caspase 3, apoptosis-related cysteine peptidase
  • Uniprot ID: P42574
  • Research Area: Metabolism
Description: Antibody raised against Caspase 3
anti- Caspase 4 antibody
FNab01291 100µg
EUR 505.25
  • Recommended dilution: WB: 1:200-1:2000
  • IHC: 1:20-1:200
  • IF: 1:50-1:500
  • Immunogen: caspase 4, apoptosis-related cysteine peptidase
  • Uniprot ID: P49662
  • Research Area: Metabolism
Description: Antibody raised against Caspase 4
anti- Caspase 6 antibody
FNab01292 100µg
EUR 548.75
  • Immunogen: caspase 6, apoptosis-related cysteine peptidase
  • Uniprot ID: P55212
  • Research Area: Metabolism
Description: Antibody raised against Caspase 6
anti- Caspase 8 antibody
FNab01293 100µg
EUR 505.25
  • Recommended dilution: WB: 1:200-1:2000
  • IP: 1:200-1:2000
  • IHC: 1:50-1:100
  • IF: 1:10-1:100
  • Immunogen: caspase 8, apoptosis-related cysteine peptidase
  • Uniprot ID: Q14790
  • Gene ID: 841
  • Research Area: Metabolism
Description: Antibody raised against Caspase 8
anti- Caspase 8 antibody
FNab01294 100µg
EUR 505.25
  • Recommended dilution: WB: 1:500-1:5000
  • IP: 1:200-1:2000
  • IHC: 1:100-1:400
  • IF: 1:50-1:500
  • Immunogen: caspase 8, apoptosis-related cysteine peptidase
  • Uniprot ID: Q14790
  • Research Area: Metabolism
Description: Antibody raised against Caspase 8
anti- Caspase 9 antibody
FNab01295 100µg
EUR 505.25
  • Recommended dilution: WB: 1:200-1:1000
  • IP: 1:200-1:1000
  • IHC: 1:50-1:200
  • IF: 1:10-1:100
  • Immunogen: caspase 9, apoptosis-related cysteine peptidase
  • Uniprot ID: P55211
  • Gene ID: 842
  • Research Area: Metabolism
Description: Antibody raised against Caspase 9
anti- Caspase 9 antibody
FNab01296 100µg
EUR 505.25
  • Recommended dilution: WB: 1:200 - 1:500
  • IHC: 1:50 - 1:200
  • IF: 1:50 - 1:100
  • Immunogen: caspase 9, apoptosis-related cysteine peptidase
  • Uniprot ID: P55211
  • Gene ID: 842
  • Research Area: Metabolism
Description: Antibody raised against Caspase 9
anti- Caspase 9 antibody
FNab01297 100µg
EUR 548.75
  • Recommended dilution: WB: 1:500-1:2000
  • IP: 1:500-1:1000
  • IHC: 1:100-1:400
  • IF: 1:50-1:500
  • Immunogen: caspase 9, apoptosis-related cysteine peptidase
  • Uniprot ID: P55211
  • Gene ID: 842
  • Research Area: Metabolism
Description: Antibody raised against Caspase 9
Anti-Caspase 1 antibody
PAab01284 100 ug
EUR 386
Anti-Caspase 10 antibody
PAab01285 100 ug
EUR 355
Anti-Caspase 2 antibody
PAab01287 100 ug
EUR 355
Anti-Caspase 2 antibody
PAab01288 100 ug
EUR 386
Anti-Caspase 3 antibody
PAab01289 100 ug
EUR 355
Anti-Caspase 4 antibody
PAab01291 100 ug
EUR 355
Anti-Caspase 6 antibody
PAab01292 100 ug
EUR 386
Anti-Caspase 8 antibody
PAab01293 100 ug
EUR 355
Anti-Caspase 9 antibody
PAab01295 100 ug
EUR 355
Anti-Caspase 9 antibody
PAab01296 100 ug
EUR 355
Anti-Caspase-4 antibody
STJ11100597 100 µl
EUR 277
Anti-Caspase-9 antibody
STJ11100939 100 µl
EUR 393
Description: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.
Anti-Caspase-3 antibody
STJ119192 100 µl
EUR 277
Description: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
Anti-Caspase-3 antibody
STJ119193 100 µl
EUR 277
Description: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
The position of BNIP3 in BECN1 dissociation from BCL2 was additional confirmed by BNIP3 overexpression or BNIP3 RNAi. Taken collectively, the endothelial protecting impact of metformin below hyperglycemia circumstances could possibly be partly attributed to its position in downregulating autophagy by way of Hh pathway activation. Abbreviations: 3-MA = 3-methyladenine; 8×GLI BS-FL = 8×GLI-binding website firefly luciferase; AAV = adeno-associated virus; AAV-Cdh5-sh-Atg7 = AAV vectors carrying shRNA in opposition to murine Atg7 below management of murine Cdh5 promoter.