Melatonin on Elevated Liver Enzymes During Statins Treatment
The Effects of Melatonin on Elevated Liver Enzymes During Statins Treatment
Introduction Statins are widely used in the treatment and prevention of lipid metabolism disorders. They are generally well tolerated but not devoid of side effects. These include, among others, muscular symptoms, arthritis, headaches, gynecomastia. Myositis and rhabdomyolysis associated with increased activity of creatinine kinase and serum creatinine levels are rare but serious adverse events of statin therapy.
- The risk of these complications is increased in elderly patients with chronic diseases and in alcohol abusers.
- Furthermore, statins cause hepatotoxic effect which is observed in several percent of treated patients, usually in the first weeks of the therapy . Most frequently it is manifested by asymptomatic increase in the level of aspartate and alanine aminotransferase.
- This is usually a temporary increase, but in some patients the level of these enzymes exceeds 3 times the normal limit, which is a matter of concern. In such cases, patients expect the decision to discontinue the treatment or to administer hepatoprotective drugs.
- Acetylcholine, sylibinin, phospholipids and other drugs used for this purpose are not always effective. Therefore, there is still search for alternative drugs for the protection of liver.
In own study melatonin was used for this purpose because previous experimental studies had demonstrated that it protected liver against harmful effects of many toxic agents as well as the consequences of ischemia-reperfusion model.
The liver is an organ in which there comes to intensive metabolic and detoxification processes. In their course large amounts of reactive oxygen species are generated and they exert a toxic effect on hepatocytes.
A complex antioxidant system – in which metabolized there melatonin (pineal and from other sources) is an important part – prevents that.
The main melatonin metabolic pathway in the liver is through hydroxylation pathway at the C-6 position by 6-hydroxylase and P450 cytochromes (CYP1A1, CYP1A2, CYP2P19, CYP1B1 isozymes). The 6-hydroxymelatonin, formed in this process, is conjugated with sulphate and glucuronide to 6-hydroxymelatonin sulphate or glucuronide. In this process melatonin and its metabolites exert high antioxidant activity.
An alternative metabolic pathway includes melatonin oxidation to N-acetyl-formyl-5- methoxykynuramine (AFMK) and N-acetyl-5-methoxykynuramine (AMK). The kynurenine pathway of melatonin metabolism leads to formation of a series of free radical scavengers.
Furthermore, melatonin decreases the production of proinflammatory cytokines and inhibits hepatic fibrogenesis. Owing to its multidirectional action in liver, apoptosis and necrosis decrease, the integrity is protected and regeneration is improved.

caspase-14
Cortisol Enzyme Immunoassay kit - 5 Whole plates |
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K003-H5W | Arbor Assays | 5x96 well plate | EUR 1266 |
FERR ( Ferritin) ELISA test |
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7 | Biobase | 96T/Box | Ask for price |
Description: ELISA based test for quantitative detection of FERR ( Ferritin) |
Human Estrone-3-Glucuronide (E1G)Enzyme Immunoassay ELISA Kit |
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QY-E05423 | Qayee Biotechnology | 96T | EUR 433.2 |
NATtrol Zika Virus Stock (Qualitative) (1 mL) |
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TEST | Zeptometrix | 1 mL | EUR 1327.97 |
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Human FE(Ferritin) ELISA Kit |
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EH0382 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Anti-SARS-CoV-2 Neutralization Antibody Test Kit (Colloidal gold immunoassay) |
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CP04010 | UnScience | 25T/kit | Ask for price |
Description: The Anti-SARS-CoV-2 Neutralization Antibody Test Kit (Serum/Plasma/Whole blood) is a qualitative membrane-based immunoassay for the detection of SARS-CoV-2 neutralizing antibodies in serum, plasma and whole blood. The sample is dropped into the sample well, and chromatography is performed under the capillary effect. The SARS-CoV-2 neutralizing antibodies in the sample combined with the colloidal gold-labeled SARS-CoV-2 spike protein(SP), then spread to the test area. It is captured by coated SP subunit RBDNTD-CTD, to form a complex and gather in the test area (T line). The quality control area is coated with mouse anti-chicken IgY, and the colloidal goldlabeled chicken IgY is captureed to form a complex and aggregate in hte quality control area (C line). If the C line does not show color, it indicates that the result is invalid, and this sample need to be tested again. |
Human FTMT(Ferritin, mitochondrial) ELISA Kit |
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EH1479 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.375 ng/ml |
Immunoassay Stabilizer |
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85R-103 | Fitzgerald | 1 liter | EUR 577.2 |
Description: Stabilizing buffer for use in immunoassays |
11,12-DHET Immunoassay Kit |
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DH4 | Detroit R&D | 1 Kit | EUR 368.4 |
Cystatin C Immunoassay Kit |
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K012-H1 | Arbor Assays | 1x96 well plate | EUR 486 |
Human FTH1(Ferritin heavy chain ) ELISA Kit |
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EH0488 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.875pg/ml |
Human FTL(Ferritin light chain ) ELISA Kit |
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EH0492 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 1.875 ng/ml |
Mouse FE(Ferritin) ELISA Kit |
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EM1019 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.281 ng/ml |
Monkey FE(Ferritin) ELISA Kit |
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EMK0022 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Ape;Sensitivity: 4.688 ng/ml |
Rat FE(Ferritin) ELISA Kit |
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ER0947 | FN Test | 96T | EUR 571.5 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 1.875pg/ml |
Human Albumin AssayLite Fluorescent Immunoassay Kit |
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FEA2201 | AssayPro | 96 Well Plate | EUR 475.2 |
Human Ceruloplasmin AssayLite Fluorescent Immunoassay Kit |
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FEC5201 | AssayPro | 96 Well Plate | EUR 475.2 |
Human Haptoglobin AssayLite Fluorescent Immunoassay Kit |
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FEH1003 | AssayPro | 96 Well Plate | EUR 475.2 |
Human IgA AssayLite Fluorescent Immunoassay Kit |
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FEI7001 | AssayPro | 96 Well Plate | EUR 475.2 |
Human IgG AssayLite Fluorescent Immunoassay Kit |
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FEI7200 | AssayPro | 96 Well Plate | EUR 475.2 |
Human IgM AssayLite Fluorescent Immunoassay Kit |
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FEI7301 | AssayPro | 96 Well Plate | EUR 475.2 |
Human Prealbumin AssayLite Fluorescent Immunoassay Kit |
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FEP2010 | AssayPro | 96 Well Plate | EUR 475.2 |
anti- Ferritin antibody |
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FNab09810 | FN Test | 100µg | EUR 658.5 |
Description: Antibody raised against Ferritin |
Human IDE(Insulin-degrading enzyme) ELISA Kit |
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EH1988 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 37.5pg/ml |
CaspSELECT Caspase 3 Immunoassay Kit |
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55R-1338 | Fitzgerald | 100 assays | EUR 1226.4 |
Description: Assay Kit for detection of Capase 3 activity in the research laboratory |
cAMP Direct Immunoassay Kit (Colorimetric) |
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K2044-100 | ApexBio | 100 assays | EUR 634.8 |
cGMP Direct Immunoassay Kit (Colorimetric) |
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K2066-100 | ApexBio | 100 assays | EUR 634.8 |
QuickTiter Adenovirus Titer Immunoassay Kit |
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VPK-109 | Cell Biolabs | 100 assays | EUR 846 |
Description: Accurate measurement of adenovirus titer is critical for gene delivery. Traditional plaque-forming unit (PFU) assays are long and suffer from high inter-assay variability. The QuickTiter Adenovirus Titer Immunoassay Kit provide a quick, complete system to functionally titer virus infectivity. The assay recognizes all 41 serotypes of adenovirus, and can be used with any adenovirus system that can amplify in HEK 293 cells. |
cAMP Direct Immunoassay Kit (Colorimetric) |
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K371-100 | Biovision | each | EUR 614.4 |
cGMP Direct Immunoassay Kit (Colorimetric) |
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K372-100 | Biovision | each | EUR 614.4 |
Human Complement C3 AssayLite Fluorescent Immunoassay Kit |
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FEC2101 | AssayPro | 96 Well Plate | EUR 475.2 |
Human Complement C4 AssayLite Fluorescent Immunoassay Kit |
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FEC2102 | AssayPro | 96 Well Plate | EUR 475.2 |
Human Fibrinogen (FBG) AssayLite Fluorescent Immunoassay Kit |
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FEF1040 | AssayPro | 96 Well Plate | EUR 475.2 |
Rat Fth1(Ferritin heavy chain) ELISA Kit |
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ER0090 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 3.75 ng/ml |
Human ECE1(Endothelin-converting enzyme 1) ELISA Kit |
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EH2454 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
Human UBE2C(Ubiquitin Conjugating Enzyme E2C) ELISA Kit |
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EH3939 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human ACE(Angiotensin I Converting Enzyme) ELISA Kit |
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EH0026 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.469 ng/ml |
Human ACE2(Angiotensin-converting enzyme 2) ELISA Kit |
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EH0027 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.234 ng/ml |
Human UBE2I(SUMO-conjugating enzyme UBC9) ELISA Kit |
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EH1264 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human APEH(Acylamino-acid-releasing enzyme) ELISA Kit |
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EH1573 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Recombinant human Glycogen debranching enzyme |
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P2412 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human Glycogen debranching enzyme |
Mouse Albumin AssayLite Fluorescent Immunoassay Kit |
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FEMA2201 | AssayPro | 96 Well Plate | EUR 475.2 |
Rat Albumin AssayLite Fluorescent Immunoassay Kit |
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FERA2201 | AssayPro | 96 Well Plate | EUR 475.2 |
CaspSELECT? Caspase-3 Immunoassay Kit (Fluorometric) |
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K163-100 | Biovision | each | EUR 901.2 |
Human Ferritin ELISA kit |
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E01F0010-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Human Ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Ferritin ELISA kit |
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E01F0010-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Human Ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Ferritin ELISA kit |
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E01F0010-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Human Ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Ferritin ELISA Kit |
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E-80F | Immunology Consultants Laboratory | 1 x 96 well plate | EUR 462 |
Human Ferritin ELISA kit |
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LF-EK0149 | Abfrontier | 1×96T | EUR 723.6 |
Ferritin (human) ELISA Kit |
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K7420-100 | Biovision | each | EUR 966 |
anti- Ferritin light chain antibody |
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FNab03079 | FN Test | 100µg | EUR 606.3 |
Description: Antibody raised against Ferritin light chain |
Immunoassay Stabilizer (BSA free) |
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85R-103BF | Fitzgerald | 1 liter | EUR 577.2 |
Description: BSA Free Stabilizing buffer for use in immunoassays |
Human SAE1(SUMO-activating enzyme subunit 1) ELISA Kit |
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EH2266 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human UBE2A(Ubiquitin-conjugating enzyme E2 A) ELISA Kit |
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EH1106 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
(1-Kit )11,12-EET/DHET Immunoassay Kit |
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DH5 | Detroit R&D | 1 Kit | EUR 368.4 |
Human Alpha-1-Antitrypsin AssayLite Fluorescent Immunoassay Kit |
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FEA5101 | AssayPro | 96 Well Plate | EUR 475.2 |
Recombinant human Acylamino-acid-releasing enzyme |
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P1835 | FN Test | 100ug | Ask for price |
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Mouse Ide(Insulin-degrading enzyme) ELISA Kit |
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EM0694 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.188 ng/ml |
Rat Ace(Angiotensin-converting enzyme) ELISA Kit |
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ER0094 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 0.188 ng/ml |
Human BACE1(Beta-site APP Cleaving Enzyme 1) ELISA Kit |
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EH2687 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.375 ng/ml |
Human UBE1L(Ubiquitin Activating Enzyme E1 Like Protein) ELISA Kit |
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EH3938 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.875pg/ml |
Human CYP11A1(Cholesterol side-chain cleavage enzyme, mitochondrial) ELISA Kit |
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EH1103 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human UBA3(NEDD8-activating enzyme E1 catalytic subunit) ELISA Kit |
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EH1150 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml |
Human Ferritin depleted/stripped serum (Ferritin |
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1810-FDS-10 | Alpha Diagnostics | 10 ml | Ask for price |
Human Ferritin depleted/stripped serum (Ferritin |
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1810-FDS-1000 | Alpha Diagnostics | 1000 ml | Ask for price |
Recombinant human NADP-dependent malic enzyme, mitochondrial |
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P2328 | FN Test | 100ug | Ask for price |
Description: Recombinant protein for human NADP-dependent malic enzyme, mitochondrial |
Anti-SARS-CoV-2 Neutralization Antibody Test Kit (Enzyme-linked immunosorbent assay) |
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CP04012 | UnScience | 96T/5*96T | Ask for price |
Description: It is a semi quantitative competition ELISA kit to detect the Anti-SARS-CoV-2 Neutralization Antibody in human serum or plasma. The micro test plate provided in this kit is pre-coated with recombinant human ACE2. During the reaction, the SARS-CoV-2 neutralization antibody in the standard & sample diluent pretreated samples or controls competes with a fixed amount of human ACE2 on the solid phase supporter for sites on the Horseradish peroxidase (HRP) conjugated recombinant SARS-CoV-2 RBD fragment (HRP-RBD). After 37℃incubation, the unbound HRP-RBD as well as any HRP-RBD bound to non-neutralization antibody will be captured on the plate and eventually form the ACE2-RBD-HRP complex, while the circulating neutralization antibodies HRP-RBD complexes remain in the supernatant and are removed during washing. Then a TMB substrate solution is added to each well. The enzyme-substrate reaction is terminated by the addition of stop solution and the color change is measured spectrophotometrically at a wavelength of 450 nm ± 2 nm. |
QuickTiter Adenovirus Titer Immunoassay Kit, Trial Size |
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VPK-109-T | Cell Biolabs | 20 assays | EUR 448.8 |
Description: Accurate measurement of adenovirus titer is critical for gene delivery. Traditional plaque-forming unit (PFU) assays are long and suffer from high inter-assay variability. The QuickTiter Adenovirus Titer Immunoassay Kit provide a quick, complete system to functionally titer virus infectivity. The assay recognizes all 41 serotypes of adenovirus, and can be used with any adenovirus system that can amplify in HEK 293 cells. |
Ferritin ELISA kit |
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55R-ORG5FE | Fitzgerald | 96 wells | EUR 415.2 |
Description: ELISA kit for the detection of Ferritin in the research laboratory |
Ferritin ELISA kit |
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55R-1881 | Fitzgerald | 1 kit | EUR 891.6 |
Description: ELISA kit for the detection of Ferritin in the research laboratory |
Human Ceruloplasmin and Haptoglobin AssayLite Multiplex Fluorescent Immunoassay Kit |
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FH100311M2 | AssayPro | 96 Well Plate | EUR 1083.6 |
Frit Kit |
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FRIT-KIT | Next Advance | 1each | EUR 148.8 |
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool. |
Mouse ACE(Angiotensin I Converting Enzyme) ELISA Kit |
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EM0011 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.188 ng/ml |
Mouse ECE1(Endothelin Converting Enzyme 1) ELISA Kit |
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EM0995 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 9.375pg/ml |
Monkey ACE(Angiotensin I Converting Enzyme) ELISA Kit |
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EMK0001 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Ape;Sensitivity: 0.094 ng/ml |
Sheep ACE(Angiotensin I Converting Enzyme) ELISA Kit |
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ESH0001 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Sheep;Sensitivity: 0.469 ng/ml |
Rat Ace2(Angiotensin-converting enzyme 2) ELISA Kit |
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ER0609 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 0.094 ng/ml |
Rat IRE1(Inositol requiring enzyme 1) ELISA Kit |
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ER1646 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus ;Sensitivity: 28.1pg/ml |
Rabbit ACE(Angiotensin I Converting Enzyme) ELISA Kit |
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ERB0001 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rabbit;Sensitivity: 0.188 ng/ml |
Human Glycosylated Ferritin ELISA kit |
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E01G0017-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Human Glycosylated Ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Glycosylated Ferritin ELISA kit |
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E01G0017-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Human Glycosylated Ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Glycosylated Ferritin ELISA kit |
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E01G0017-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Human Glycosylated Ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human H ferritin ELISA kit |
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E01H0243-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Human H ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human H ferritin ELISA kit |
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E01H0243-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Human H ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human H ferritin ELISA kit |
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E01H0243-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Human H ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Carcinoembryonic Ferritin ELISA kit |
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E01C0729-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Human Carcinoembryonic Ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Carcinoembryonic Ferritin ELISA kit |
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E01C0729-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Human Carcinoembryonic Ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Carcinoembryonic Ferritin ELISA kit |
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E01C0729-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Human Carcinoembryonic Ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human ferritin, FE ELISA Kit |
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CSB-E05187h-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
Description: Quantitative sandwich ELISA kit for measuring Human ferritin, FE in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Human ferritin, FE ELISA Kit |
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1-CSB-E05187h | Cusabio |
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Description: Quantitative sandwich ELISA kit for measuring Human ferritin, FE in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Human ferritin,FE ELISA Kit |
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CN-04117H1 | ChemNorm | 96T | EUR 520.8 |
Human ferritin,FE ELISA Kit |
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CN-04117H2 | ChemNorm | 48T | EUR 340.8 |
Human Ferritin OneStep ELISA Kit |
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EK7055 | BosterBio | 96wells/kit, with removable strips. | EUR 573.6 |
The aim of this study was to assess the usefulness of melatonin in counteracting the adverse hepatic events from statins.
Material and Methods Patients and Data Collection The research program included 30 subjects, aged 47-68 years, 41 women and 23 men. All women were I the postpostmenopausal period. Recruitment and diagnostic tests were conducted in the Department of Gastroenterology, Medical University of Lodz and Outpatient Consulting Clinic “Gastro” in Lodz.
The research study was performed in the years 2012-2016. Therapeutic Procedures After inclusion into the study, all patients were recommended the same balanced diet with limited animal fats and simple carbohydrates of caloric content of 1600 kcal. At the same time, they were recommended to continue the treatment with the same statin at a daily dose of 20 mg.
The patients were randomly allocated into two groups. Group I (n=30) was recommended to take statin together with melatonin (LEK-AM, Poland) at a dose of 2×5 mg, at 7:00 a.m. and 9:00 p.m. In Group II (n=30) patients took statin with placebo (LEK-AM, Poland) at the same dose and time of the day.
Follow-up laboratory tests (AST, ALT, GGT, ALP, cholesterol and triglycerides) were evaluated after 2,4 and 6 months of treatment.
Ethical procedures A written consent was obtained from the patients and the Bioethics Committee of the Medical University in Lodz approved the study protocol (RNN/45/12/KB).
Tests were conducted in accordance with the Declaration of Helsinki and with the principles of Good Clinical Practice.
Statistical analysis All parameters were checked for normality using the Shapiro-Wilk test. Wilcoxon’s rank sum test was used for the comparison of basal treatment differences between each liver enzyme level.
Comparison of parameters in four time series was calculated using ANOVA Friedman test. Mann-Whitney U test was used for nonparametric data to perform the comparison between groups. Calculation were made using Statistical 9.1 Microsoft Co. software, and statistical significance was established at p< 0,05.
Acknowledgments This work was supported by the grant from the Polish Ministry of Science and Higher Education No: NN 402 54 37/40.
Competing Interests The authors declare that they have no competing interests.
Angiotensin-Converting Enzyme (CD143) Antibody |
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abx413653-1ml | Abbexa | 1 ml | EUR 1228.8 |
ACE Antibody [Angiotensin Converting Enzyme] |
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R31318 | NSJ Bioreagents | 100 ug | EUR 419 |
Angiotensin Converting Enzyme Antibody (ACE) |
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R31319 | NSJ Bioreagents | 100 ug | EUR 419 |
Angiotensin-converting enzyme Antibody (Ace) |
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RQ4007 | NSJ Bioreagents | 100 ug | EUR 419 |
Angiotensin-converting enzyme 2 Antibody |
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F49434-0.4ML | NSJ Bioreagents | 0.4 ml | EUR 379 |
Angiotensin Converting Enzyme Antibody (ACE) |
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F50773-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 165 |
ACE Antibody / Angiotensin-Converting Enzyme |
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RQ5388 | NSJ Bioreagents | 100 ul | EUR 419 |
Angiotensin I Converting Enzyme (ACE) Antibody |
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abx159297-100ul | Abbexa | 100 ul | EUR 560.4 |
Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx171229 | Abbexa |
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Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx171230 | Abbexa |
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Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx171231 | Abbexa |
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Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx171232 | Abbexa |
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Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx171233 | Abbexa |
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Angiotensin I Converting Enzyme (ACE) Antibody |
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abx140499-01mg | Abbexa | 0.1 mg | EUR 427.2 |
Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx103103 | Abbexa |
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Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx103104 | Abbexa |
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Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx103105 | Abbexa |
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Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx007362 | Abbexa |
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Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx128667 | Abbexa |
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Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx129494 | Abbexa |
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Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx129607 | Abbexa |
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Angiotensin I Converting Enzyme (ACE) Antibody |
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abx033685-400ul | Abbexa | 400 ul | EUR 627.6 |
Angiotensin I Converting Enzyme (ACE) Antibody |
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abx033685-80l | Abbexa | 80 µl | EUR 343.2 |
Angiotensin I Converting Enzyme (ACE) Antibody |
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abx037354-100ug | Abbexa | 100 ug | EUR 469.2 |
Angiotensin I Converting Enzyme (ACE) Antibody |
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abx025482-100ul | Abbexa | 100 ul | EUR 627.6 |
Angiotensin I-Converting Enzyme Substrate Peptide |
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20-abx265670 | Abbexa |
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Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx270178 | Abbexa |
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Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx270179 | Abbexa |
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Angiotensin I Converting Enzyme (ACE) Antibody |
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abx230080-100ug | Abbexa | 100 ug | EUR 577.2 |
Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx241727 | Abbexa |
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Angiotensin-Converting Enzyme 2 (ACE2) Antibody |
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20-abx313823 | Abbexa |
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Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx325361 | Abbexa |
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Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx328371 | Abbexa |
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Angiotensin-Converting Enzyme (CD143) Antibody (FITC) |
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abx413654-01mg | Abbexa | 0.1 mg | EUR 693.6 |
Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx214211 | Abbexa |
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Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx241080 | Abbexa |
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Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx241081 | Abbexa |
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Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx175391 | Abbexa |
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Angiotensin I Converting Enzyme (ACE) Antibody |
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20-abx175393 | Abbexa |
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Active Angiotensin I Converting Enzyme (ACE) |
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4-APA004Hu02 | Cloud-Clone |
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Description: Recombinant Human Angiotensin I Converting Enzyme expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells |
Angiotensin Converting Enzyme 2 Conjugated Antibody |
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C49072 | SAB | 100ul | EUR 476.4 |
Monoclonal Angiotensin Converting Enzyme 1 Antibody |
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APG01871G | Leading Biology | 0.1ml | EUR 580.8 |
Description: A Monoclonal antibody against Human Angiotensin Converting Enzyme 1. The antibodies are raised in Mouse. This antibody is applicable in WB |
Rabbit Angiotensin Converting Enzyme ELISA kit |
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E04A2159-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive for quantitative measurement of Rabbit Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Angiotensin Converting Enzyme ELISA kit |
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E04A2159-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive for quantitative measurement of Rabbit Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Angiotensin Converting Enzyme ELISA kit |
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E04A2159-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive for quantitative measurement of Rabbit Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Angiotensin I-Converting Enzyme (ACE) Inactivator |
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N-1360.0250 | Bachem | 250.0mg | EUR 691.2 |
Description: Sum Formula: C21H21N3O4; CAS# [144085-32-5] |
Angiotensin I-Converting Enzyme (ACE) Inactivator |
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N-1360.1000 | Bachem | 1.0g | EUR 1995.6 |
Description: Sum Formula: C21H21N3O4; CAS# [144085-32-5] |
Pig Angiotensin Converting Enzyme ELISA kit |
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E07A2159-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive for quantitative measurement of Porcine Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Angiotensin Converting Enzyme ELISA kit |
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E07A2159-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive for quantitative measurement of Porcine Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Angiotensin Converting Enzyme ELISA kit |
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E07A2159-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive for quantitative measurement of Porcine Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Angiotensin Converting Enzyme ELISA kit |
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E01A2159-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive for quantitative measurement of Human Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Angiotensin Converting Enzyme ELISA kit |
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E01A2159-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive for quantitative measurement of Human Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Angiotensin Converting Enzyme ELISA kit |
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E01A2159-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive for quantitative measurement of Human Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Angiotensin Converting Enzyme ELISA kit |
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E06A2159-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive for quantitative measurement of Goat Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Angiotensin Converting Enzyme ELISA kit |
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E06A2159-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive for quantitative measurement of Goat Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Angiotensin Converting Enzyme ELISA kit |
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E06A2159-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive for quantitative measurement of Goat Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Angiotensin Converting Enzyme ELISA kit |
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E03A2159-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive for quantitative measurement of Mouse Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Angiotensin Converting Enzyme ELISA kit |
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E03A2159-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive for quantitative measurement of Mouse Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Angiotensin Converting Enzyme ELISA kit |
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E03A2159-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive for quantitative measurement of Mouse Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Angiotensin Converting Enzyme ELISA kit |
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E08A2159-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive for quantitative measurement of Canine Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Angiotensin Converting Enzyme ELISA kit |
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E08A2159-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive for quantitative measurement of Canine Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Angiotensin Converting Enzyme ELISA kit |
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E08A2159-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive for quantitative measurement of Canine Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Angiotensin Converting Enzyme ELISA kit |
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E02A2159-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive for quantitative measurement of Rat Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Angiotensin Converting Enzyme ELISA kit |
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E02A2159-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive for quantitative measurement of Rat Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Angiotensin Converting Enzyme ELISA kit |
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E02A2159-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive for quantitative measurement of Rat Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Angiotensin Converting Enzyme ELISA kit |
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E09A2159-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive for quantitative measurement of Monkey Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Angiotensin Converting Enzyme ELISA kit |
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E09A2159-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive for quantitative measurement of Monkey Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Angiotensin Converting Enzyme ELISA kit |
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E09A2159-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive for quantitative measurement of Monkey Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Anti-Angiotensin Converting Enzyme 1 antibody |
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STJ99092 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Mouse monoclonal to Angiotensin Converting Enzyme 1. |
Recombinant Angiotensin I Converting Enzyme (ACE) |
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4-RPA004Hu01 | Cloud-Clone |
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Description: Recombinant Human Angiotensin I Converting Enzyme expressed in: E.coli |
Recombinant Angiotensin I Converting Enzyme (ACE) |
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4-RPA004Hu02 | Cloud-Clone |
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Description: Recombinant Human Angiotensin I Converting Enzyme expressed in: E.coli |
Recombinant Angiotensin I Converting Enzyme (ACE) |
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4-RPA004Mu01 | Cloud-Clone |
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Description: Recombinant Mouse Angiotensin I Converting Enzyme expressed in: E.coli |
Recombinant Angiotensin I Converting Enzyme (ACE) |
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4-RPA004Mu02 | Cloud-Clone |
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Description: Recombinant Mouse Angiotensin I Converting Enzyme expressed in: E.coli |
Recombinant Angiotensin I Converting Enzyme (ACE) |
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4-RPA004Mu03 | Cloud-Clone |
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Description: Recombinant Mouse Angiotensin I Converting Enzyme expressed in: E.coli |
Recombinant Angiotensin I Converting Enzyme (ACE) |
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4-RPA004Po01 | Cloud-Clone |
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Description: Recombinant Pig Angiotensin I Converting Enzyme expressed in: E.coli |
Recombinant Angiotensin I Converting Enzyme (ACE) |
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4-RPA004Rb01 | Cloud-Clone |
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Description: Recombinant Rabbit Angiotensin I Converting Enzyme expressed in: E.coli |
Anti-Angiotensin Converting Enzyme 1 (6A4) |
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YF-MA12650 | Abfrontier | 100 ug | EUR 435.6 |
Description: Mouse monoclonal to Angiotensin Converting Enzyme 1 |
Anti-Angiotensin Converting Enzyme 1 (4B10) |
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YF-MA12651 | Abfrontier | 100 ug | EUR 435.6 |
Description: Mouse monoclonal to Angiotensin Converting Enzyme 1 |
Angiotensin-Converting Enzyme 2 Antibody (ACE2) |
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F49434-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 165 |
Angiotensin-Converting Enzyme 2 Antibody (ACE2) |
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F52229-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 165 |
ACE Antibody / Angiotensin I Converting Enzyme |
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V8490-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. |
ACE Antibody / Angiotensin I Converting Enzyme |
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V8490-20UG | NSJ Bioreagents | 20 ug | EUR 219 |
Description: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. |
ACE Antibody / Angiotensin I Converting Enzyme |
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V8490SAF-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. |
ACE Antibody / Angiotensin I Converting Enzyme |
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V8534-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. |
ACE Antibody / Angiotensin I Converting Enzyme |
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V8534-20UG | NSJ Bioreagents | 20 ug | EUR 219 |
Description: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. |
ACE Antibody / Angiotensin I Converting Enzyme |
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V8534SAF-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. |
ACE Antibody / Angiotensin I Converting Enzyme |
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V8535-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. |
ACE Antibody / Angiotensin I Converting Enzyme |
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V8535-20UG | NSJ Bioreagents | 20 ug | EUR 219 |
Description: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. |
ACE Antibody / Angiotensin I Converting Enzyme |
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V8535SAF-100UG | NSJ Bioreagents | 100 ug | EUR 499 |
Description: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined. |