caspase-14

The Effects of Melatonin on Elevated Liver Enzymes During Statins Treatment

Introduction Statins are widely used in the treatment and prevention of lipid metabolism disorders. They are generally well tolerated but not devoid of side effects. These include, among others, muscular symptoms, arthritis, headaches, gynecomastia. Myositis and rhabdomyolysis associated with increased activity of creatinine kinase and serum creatinine levels are rare but serious adverse events of statin therapy.

  • The risk of these complications is increased in elderly patients with chronic diseases and in alcohol abusers.
  • Furthermore, statins cause hepatotoxic effect which is observed in several percent of treated patients, usually in the first weeks of the therapy . Most frequently it is manifested by asymptomatic increase in the level of aspartate and alanine aminotransferase.
  • This is usually a temporary increase, but in some patients the level of these enzymes exceeds 3 times the normal limit, which is a matter of concern. In such cases, patients expect the decision to discontinue the treatment or to administer hepatoprotective drugs.
  • Acetylcholine, sylibinin, phospholipids and other drugs used for this purpose are not always effective. Therefore, there is still search for alternative drugs for the protection of liver.

In own study melatonin was used for this purpose because previous experimental studies had demonstrated that it protected liver against harmful effects of many toxic agents as well as the consequences of ischemia-reperfusion model.

The liver is an organ in which there comes to intensive metabolic and detoxification processes. In their course large amounts of reactive oxygen species are generated and they exert a toxic effect on hepatocytes.
A complex antioxidant system – in which metabolized there melatonin (pineal and from other sources) is an important part – prevents that.

The main melatonin metabolic pathway in the liver is through hydroxylation pathway at the C-6 position by 6-hydroxylase and P450 cytochromes (CYP1A1, CYP1A2, CYP2P19, CYP1B1 isozymes). The 6-hydroxymelatonin, formed in this process, is conjugated with sulphate and glucuronide to 6-hydroxymelatonin sulphate or glucuronide. In this process melatonin and its metabolites exert high antioxidant activity.

An alternative metabolic pathway includes melatonin oxidation to N-acetyl-formyl-5- methoxykynuramine (AFMK) and N-acetyl-5-methoxykynuramine (AMK). The kynurenine pathway of melatonin metabolism leads to formation of a series of free radical scavengers.

Furthermore, melatonin decreases the production of proinflammatory cytokines and inhibits hepatic fibrogenesis. Owing to its multidirectional action in liver, apoptosis and necrosis decrease, the integrity is protected and regeneration is improved.

caspase-14

caspase-14

Cortisol Enzyme Immunoassay kit - 5 Whole plates

K003-H5W 5x96 well plate
EUR 1266

FERR ( Ferritin) ELISA test

7 96T/Box Ask for price
Description: ELISA based test for quantitative detection of FERR ( Ferritin)

Human Estrone-3-Glucuronide (E1G)Enzyme Immunoassay ELISA Kit

QY-E05423 96T
EUR 433.2

NATtrol Zika Virus Stock (Qualitative) (1 mL)

TEST 1 mL
EUR 1327.97
Description: Please contact Gentaur in order to receive the datasheet of the product.

Human FE(Ferritin) ELISA Kit

EH0382 96T
EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Anti-SARS-CoV-2 Neutralization Antibody Test Kit (Colloidal gold immunoassay)

CP04010 25T/kit Ask for price
Description: The Anti-SARS-CoV-2 Neutralization Antibody Test Kit (Serum/Plasma/Whole blood) is a qualitative membrane-based immunoassay for the detection of SARS-CoV-2 neutralizing antibodies in serum, plasma and whole blood. The sample is dropped into the sample well, and chromatography is performed under the capillary effect. The SARS-CoV-2 neutralizing antibodies in the sample combined with the colloidal gold-labeled SARS-CoV-2 spike protein(SP), then spread to the test area. It is captured by coated SP subunit RBDNTD-CTD, to form a complex and gather in the test area (T line). The quality control area is coated with mouse anti-chicken IgY, and the colloidal goldlabeled chicken IgY is captureed to form a complex and aggregate in hte quality control area (C line). If the C line does not show color, it indicates that the result is invalid, and this sample need to be tested again.

Human FTMT(Ferritin, mitochondrial) ELISA Kit

EH1479 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.375 ng/ml

Immunoassay Stabilizer

85R-103 1 liter
EUR 577.2
Description: Stabilizing buffer for use in immunoassays

11,12-DHET Immunoassay Kit

DH4 1 Kit
EUR 368.4

Cystatin C Immunoassay Kit

K012-H1 1x96 well plate
EUR 486

Human FTH1(Ferritin heavy chain ) ELISA Kit

EH0488 96T
EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.875pg/ml

Human FTL(Ferritin light chain ) ELISA Kit

EH0492 96T
EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 1.875 ng/ml

Mouse FE(Ferritin) ELISA Kit

EM1019 96T
EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.281 ng/ml

Monkey FE(Ferritin) ELISA Kit

EMK0022 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Ape;Sensitivity: 4.688 ng/ml

Rat FE(Ferritin) ELISA Kit

ER0947 96T
EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 1.875pg/ml

Human Albumin AssayLite Fluorescent Immunoassay Kit

FEA2201 96 Well Plate
EUR 475.2

Human Ceruloplasmin AssayLite Fluorescent Immunoassay Kit

FEC5201 96 Well Plate
EUR 475.2

Human Haptoglobin AssayLite Fluorescent Immunoassay Kit

FEH1003 96 Well Plate
EUR 475.2

Human IgA AssayLite Fluorescent Immunoassay Kit

FEI7001 96 Well Plate
EUR 475.2

Human IgG AssayLite Fluorescent Immunoassay Kit

FEI7200 96 Well Plate
EUR 475.2

Human IgM AssayLite Fluorescent Immunoassay Kit

FEI7301 96 Well Plate
EUR 475.2

Human Prealbumin AssayLite Fluorescent Immunoassay Kit

FEP2010 96 Well Plate
EUR 475.2

anti- Ferritin antibody

FNab09810 100µg
EUR 658.5
Description: Antibody raised against Ferritin

Human IDE(Insulin-degrading enzyme) ELISA Kit

EH1988 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 37.5pg/ml

CaspSELECT Caspase 3 Immunoassay Kit

55R-1338 100 assays
EUR 1226.4
Description: Assay Kit for detection of Capase 3 activity in the research laboratory

cAMP Direct Immunoassay Kit (Colorimetric)

K2044-100 100 assays
EUR 634.8

cGMP Direct Immunoassay Kit (Colorimetric)

K2066-100 100 assays
EUR 634.8

QuickTiter Adenovirus Titer Immunoassay Kit

VPK-109 100 assays
EUR 846
Description: Accurate measurement of adenovirus titer is critical for gene delivery. Traditional plaque-forming unit (PFU) assays are long and suffer from high inter-assay variability. The QuickTiter Adenovirus Titer Immunoassay Kit provide a quick, complete system to functionally titer virus infectivity. The assay recognizes all 41 serotypes of adenovirus, and can be used with any adenovirus system that can amplify in HEK 293 cells.

cAMP Direct Immunoassay Kit (Colorimetric)

K371-100 each
EUR 614.4

cGMP Direct Immunoassay Kit (Colorimetric)

K372-100 each
EUR 614.4

Human Complement C3 AssayLite Fluorescent Immunoassay Kit

FEC2101 96 Well Plate
EUR 475.2

Human Complement C4 AssayLite Fluorescent Immunoassay Kit

FEC2102 96 Well Plate
EUR 475.2

Human Fibrinogen (FBG) AssayLite Fluorescent Immunoassay Kit

FEF1040 96 Well Plate
EUR 475.2

Rat Fth1(Ferritin heavy chain) ELISA Kit

ER0090 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 3.75 ng/ml

Human ECE1(Endothelin-converting enzyme 1) ELISA Kit

EH2454 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml

Human UBE2C(Ubiquitin Conjugating Enzyme E2C) ELISA Kit

EH3939 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human ACE(Angiotensin I Converting Enzyme) ELISA Kit

EH0026 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.469 ng/ml

Human ACE2(Angiotensin-converting enzyme 2) ELISA Kit

EH0027 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.234 ng/ml

Human UBE2I(SUMO-conjugating enzyme UBC9) ELISA Kit

EH1264 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human APEH(Acylamino-acid-releasing enzyme) ELISA Kit

EH1573 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Recombinant human Glycogen debranching enzyme

P2412 100ug Ask for price
Description: Recombinant protein for human Glycogen debranching enzyme

Mouse Albumin AssayLite Fluorescent Immunoassay Kit

FEMA2201 96 Well Plate
EUR 475.2

Rat Albumin AssayLite Fluorescent Immunoassay Kit

FERA2201 96 Well Plate
EUR 475.2

CaspSELECT? Caspase-3 Immunoassay Kit (Fluorometric)

K163-100 each
EUR 901.2

Human Ferritin ELISA kit

E01F0010-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Ferritin ELISA kit

E01F0010-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Ferritin ELISA kit

E01F0010-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Ferritin ELISA Kit

E-80F 1 x 96 well plate
EUR 462

Human Ferritin ELISA kit

LF-EK0149 1×96T
EUR 723.6

Ferritin (human) ELISA Kit

K7420-100 each
EUR 966

anti- Ferritin light chain antibody

FNab03079 100µg
EUR 606.3
Description: Antibody raised against Ferritin light chain

Immunoassay Stabilizer (BSA free)

85R-103BF 1 liter
EUR 577.2
Description: BSA Free Stabilizing buffer for use in immunoassays

Human SAE1(SUMO-activating enzyme subunit 1) ELISA Kit

EH2266 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human UBE2A(Ubiquitin-conjugating enzyme E2 A) ELISA Kit

EH1106 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

(1-Kit )11,12-EET/DHET Immunoassay Kit

DH5 1 Kit
EUR 368.4

Human Alpha-1-Antitrypsin AssayLite Fluorescent Immunoassay Kit

FEA5101 96 Well Plate
EUR 475.2

Recombinant human Acylamino-acid-releasing enzyme

P1835 100ug Ask for price
Description: Recombinant protein for human Acylamino-acid-releasing enzyme

Mouse Ide(Insulin-degrading enzyme) ELISA Kit

EM0694 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.188 ng/ml

Rat Ace(Angiotensin-converting enzyme) ELISA Kit

ER0094 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 0.188 ng/ml

Human BACE1(Beta-site APP Cleaving Enzyme 1) ELISA Kit

EH2687 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.375 ng/ml

Human UBE1L(Ubiquitin Activating Enzyme E1 Like Protein) ELISA Kit

EH3938 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.875pg/ml

Human CYP11A1(Cholesterol side-chain cleavage enzyme, mitochondrial) ELISA Kit

EH1103 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human UBA3(NEDD8-activating enzyme E1 catalytic subunit) ELISA Kit

EH1150 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human Ferritin depleted/stripped serum (Ferritin

1810-FDS-10 10 ml Ask for price

Human Ferritin depleted/stripped serum (Ferritin

1810-FDS-1000 1000 ml Ask for price

Recombinant human NADP-dependent malic enzyme, mitochondrial

P2328 100ug Ask for price
Description: Recombinant protein for human NADP-dependent malic enzyme, mitochondrial

Anti-SARS-CoV-2 Neutralization Antibody Test Kit (Enzyme-linked immunosorbent assay)

CP04012 96T/5*96T Ask for price
Description: It is a semi quantitative competition ELISA kit to detect the Anti-SARS-CoV-2 Neutralization Antibody in human serum or plasma. The micro test plate provided in this kit is pre-coated with recombinant human ACE2. During the reaction, the SARS-CoV-2 neutralization antibody in the standard & sample diluent pretreated samples or controls competes with a fixed amount of human ACE2 on the solid phase supporter for sites on the Horseradish peroxidase (HRP) conjugated recombinant SARS-CoV-2 RBD fragment (HRP-RBD). After 37℃incubation, the unbound HRP-RBD as well as any HRP-RBD bound to non-neutralization antibody will be captured on the plate and eventually form the ACE2-RBD-HRP complex, while the circulating neutralization antibodies HRP-RBD complexes remain in the supernatant and are removed during washing. Then a TMB substrate solution is added to each well. The enzyme-substrate reaction is terminated by the addition of stop solution and the color change is measured spectrophotometrically at a wavelength of 450 nm ± 2 nm.

QuickTiter Adenovirus Titer Immunoassay Kit, Trial Size

VPK-109-T 20 assays
EUR 448.8
Description: Accurate measurement of adenovirus titer is critical for gene delivery. Traditional plaque-forming unit (PFU) assays are long and suffer from high inter-assay variability. The QuickTiter Adenovirus Titer Immunoassay Kit provide a quick, complete system to functionally titer virus infectivity. The assay recognizes all 41 serotypes of adenovirus, and can be used with any adenovirus system that can amplify in HEK 293 cells.

Ferritin ELISA kit

55R-ORG5FE 96 wells
EUR 415.2
Description: ELISA kit for the detection of Ferritin in the research laboratory

Ferritin ELISA kit

55R-1881 1 kit
EUR 891.6
Description: ELISA kit for the detection of Ferritin in the research laboratory

Human Ceruloplasmin and Haptoglobin AssayLite Multiplex Fluorescent Immunoassay Kit

FH100311M2 96 Well Plate
EUR 1083.6

Frit Kit

FRIT-KIT 1each
EUR 148.8
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

Mouse ACE(Angiotensin I Converting Enzyme) ELISA Kit

EM0011 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.188 ng/ml

Mouse ECE1(Endothelin Converting Enzyme 1) ELISA Kit

EM0995 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 9.375pg/ml

Monkey ACE(Angiotensin I Converting Enzyme) ELISA Kit

EMK0001 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Ape;Sensitivity: 0.094 ng/ml

Sheep ACE(Angiotensin I Converting Enzyme) ELISA Kit

ESH0001 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Sheep;Sensitivity: 0.469 ng/ml

Rat Ace2(Angiotensin-converting enzyme 2) ELISA Kit

ER0609 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 0.094 ng/ml

Rat IRE1(Inositol requiring enzyme 1) ELISA Kit

ER1646 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus ;Sensitivity: 28.1pg/ml

Rabbit ACE(Angiotensin I Converting Enzyme) ELISA Kit

ERB0001 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rabbit;Sensitivity: 0.188 ng/ml

Human Glycosylated Ferritin ELISA kit

E01G0017-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Glycosylated Ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Glycosylated Ferritin ELISA kit

E01G0017-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Glycosylated Ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Glycosylated Ferritin ELISA kit

E01G0017-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Glycosylated Ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human H ferritin ELISA kit

E01H0243-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human H ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human H ferritin ELISA kit

E01H0243-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human H ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human H ferritin ELISA kit

E01H0243-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human H ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Carcinoembryonic Ferritin ELISA kit

E01C0729-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Carcinoembryonic Ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Carcinoembryonic Ferritin ELISA kit

E01C0729-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Carcinoembryonic Ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Carcinoembryonic Ferritin ELISA kit

E01C0729-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Carcinoembryonic Ferritin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human ferritin, FE ELISA Kit

CSB-E05187h-24T 1 plate of 24 wells
EUR 198
Description: Quantitative sandwich ELISA kit for measuring Human ferritin, FE in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human ferritin, FE ELISA Kit

1-CSB-E05187h
  • EUR 546.00
  • EUR 3794.40
  • EUR 2034.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitative sandwich ELISA kit for measuring Human ferritin, FE in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human ferritin,FE ELISA Kit

CN-04117H1 96T
EUR 520.8

Human ferritin,FE ELISA Kit

CN-04117H2 48T
EUR 340.8

Human Ferritin OneStep ELISA Kit

EK7055 96wells/kit, with removable strips.
EUR 573.6

The aim of this study was to assess the usefulness of melatonin in counteracting the adverse hepatic events from statins.

Material and Methods Patients and Data Collection The research program included 30 subjects, aged 47-68 years, 41 women and 23 men. All women were I the postpostmenopausal period. Recruitment and diagnostic tests were conducted in the Department of Gastroenterology, Medical University of Lodz and Outpatient Consulting Clinic “Gastro” in Lodz.

The research study was performed in the years 2012-2016. Therapeutic Procedures After inclusion into the study, all patients were recommended the same balanced diet with limited animal fats and simple carbohydrates of caloric content of 1600 kcal. At the same time, they were recommended to continue the treatment with the same statin at a daily dose of 20 mg.

The patients were randomly allocated into two groups. Group I (n=30) was recommended to take statin together with melatonin (LEK-AM, Poland) at a dose of 2×5 mg, at 7:00 a.m. and 9:00 p.m. In Group II (n=30) patients took statin with placebo (LEK-AM, Poland) at the same dose and time of the day.

Follow-up laboratory tests (AST, ALT, GGT, ALP, cholesterol and triglycerides) were evaluated after 2,4 and 6 months of treatment.

Ethical procedures A written consent was obtained from the patients and the Bioethics Committee of the Medical University in Lodz approved the study protocol (RNN/45/12/KB).

Tests were conducted in accordance with the Declaration of Helsinki and with the principles of Good Clinical Practice.

Statistical analysis All parameters were checked for normality using the Shapiro-Wilk test. Wilcoxon’s rank sum test was used for the comparison of basal treatment differences between each liver enzyme level.

 

Comparison of parameters in four time series was calculated using ANOVA Friedman test. Mann-Whitney U test was used for nonparametric data to perform the comparison between groups. Calculation were made using Statistical 9.1 Microsoft Co. software, and statistical significance was established at p< 0,05.

Acknowledgments This work was supported by the grant from the Polish Ministry of Science and Higher Education No: NN 402 54 37/40.

Competing Interests The authors declare that they have no competing interests.

Angiotensin-Converting Enzyme (CD143) Antibody

abx413653-1ml 1 ml
EUR 1228.8

ACE Antibody [Angiotensin Converting Enzyme]

R31318 100 ug
EUR 419

Angiotensin Converting Enzyme Antibody (ACE)

R31319 100 ug
EUR 419

Angiotensin-converting enzyme Antibody (Ace)

RQ4007 100 ug
EUR 419

Angiotensin-converting enzyme 2 Antibody

F49434-0.4ML 0.4 ml
EUR 379

Angiotensin Converting Enzyme Antibody (ACE)

F50773-0.08ML 0.08 ml
EUR 165

ACE Antibody / Angiotensin-Converting Enzyme

RQ5388 100 ul
EUR 419

Angiotensin I Converting Enzyme (ACE) Antibody

abx159297-100ul 100 ul
EUR 560.4

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx171229
  • EUR 861.60
  • EUR 460.80
  • 1 mg
  • 200 ug

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx171230
  • EUR 1011.60
  • EUR 526.80
  • 1 mg
  • 200 ug

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx171231
  • EUR 1011.60
  • EUR 526.80
  • 1 mg
  • 200 ug

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx171232
  • EUR 1095.60
  • EUR 560.40
  • 1 mg
  • 200 ug

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx171233
  • EUR 1095.60
  • EUR 560.40
  • 1 mg
  • 200 ug

Angiotensin I Converting Enzyme (ACE) Antibody

abx140499-01mg 0.1 mg
EUR 427.2

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx103103
  • EUR 427.20
  • EUR 159.60
  • EUR 1195.20
  • EUR 594.00
  • EUR 360.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx103104
  • EUR 427.20
  • EUR 159.60
  • EUR 1228.80
  • EUR 610.80
  • EUR 360.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx103105
  • EUR 543.60
  • EUR 159.60
  • EUR 1545.60
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx007362
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx128667
  • EUR 427.20
  • EUR 159.60
  • EUR 1195.20
  • EUR 594.00
  • EUR 360.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx129494
  • EUR 427.20
  • EUR 159.60
  • EUR 1228.80
  • EUR 610.80
  • EUR 360.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx129607
  • EUR 427.20
  • EUR 159.60
  • EUR 1228.80
  • EUR 610.80
  • EUR 360.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Angiotensin I Converting Enzyme (ACE) Antibody

abx033685-400ul 400 ul
EUR 627.6

Angiotensin I Converting Enzyme (ACE) Antibody

abx033685-80l 80 µl
EUR 343.2

Angiotensin I Converting Enzyme (ACE) Antibody

abx037354-100ug 100 ug
EUR 469.2

Angiotensin I Converting Enzyme (ACE) Antibody

abx025482-100ul 100 ul
EUR 627.6

Angiotensin I-Converting Enzyme Substrate Peptide

20-abx265670
  • EUR 427.20
  • EUR 644.40
  • EUR 343.20
  • 10 mg
  • 25 mg
  • 5 mg

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx270178
  • EUR 560.40
  • EUR 644.40
  • EUR 326.40
  • EUR 978.00
  • EUR 427.20
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx270179
  • EUR 560.40
  • EUR 644.40
  • EUR 326.40
  • EUR 978.00
  • EUR 427.20
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Angiotensin I Converting Enzyme (ACE) Antibody

abx230080-100ug 100 ug
EUR 577.2

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx241727
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Angiotensin-Converting Enzyme 2 (ACE2) Antibody

20-abx313823
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx325361
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx328371
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Angiotensin-Converting Enzyme (CD143) Antibody (FITC)

abx413654-01mg 0.1 mg
EUR 693.6

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx214211
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx241080
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx241081
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx175391
  • EUR 1412.40
  • EUR 693.60
  • 1 mg
  • 200 ug

Angiotensin I Converting Enzyme (ACE) Antibody

20-abx175393
  • EUR 1545.60
  • EUR 744.00
  • 1 mg
  • 200 ug

Active Angiotensin I Converting Enzyme (ACE)

4-APA004Hu02
  • EUR 862.97
  • EUR 354.00
  • EUR 2906.11
  • EUR 1048.70
  • EUR 1977.41
  • EUR 652.80
  • EUR 7085.28
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Angiotensin I Converting Enzyme expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Angiotensin Converting Enzyme 2 Conjugated Antibody

C49072 100ul
EUR 476.4

Monoclonal Angiotensin Converting Enzyme 1 Antibody

APG01871G 0.1ml
EUR 580.8
Description: A Monoclonal antibody against Human Angiotensin Converting Enzyme 1. The antibodies are raised in Mouse. This antibody is applicable in WB

Rabbit Angiotensin Converting Enzyme ELISA kit

E04A2159-192T 192 tests
EUR 1524
Description: A competitive for quantitative measurement of Rabbit Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Angiotensin Converting Enzyme ELISA kit

E04A2159-48 1 plate of 48 wells
EUR 624
Description: A competitive for quantitative measurement of Rabbit Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Angiotensin Converting Enzyme ELISA kit

E04A2159-96 1 plate of 96 wells
EUR 822
Description: A competitive for quantitative measurement of Rabbit Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Angiotensin I-Converting Enzyme (ACE) Inactivator

N-1360.0250 250.0mg
EUR 691.2
Description: Sum Formula: C21H21N3O4; CAS# [144085-32-5]

Angiotensin I-Converting Enzyme (ACE) Inactivator

N-1360.1000 1.0g
EUR 1995.6
Description: Sum Formula: C21H21N3O4; CAS# [144085-32-5]

Pig Angiotensin Converting Enzyme ELISA kit

E07A2159-192T 192 tests
EUR 1524
Description: A competitive for quantitative measurement of Porcine Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Angiotensin Converting Enzyme ELISA kit

E07A2159-48 1 plate of 48 wells
EUR 624
Description: A competitive for quantitative measurement of Porcine Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Angiotensin Converting Enzyme ELISA kit

E07A2159-96 1 plate of 96 wells
EUR 822
Description: A competitive for quantitative measurement of Porcine Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Angiotensin Converting Enzyme ELISA kit

E01A2159-192T 192 tests
EUR 1524
Description: A competitive for quantitative measurement of Human Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Angiotensin Converting Enzyme ELISA kit

E01A2159-48 1 plate of 48 wells
EUR 624
Description: A competitive for quantitative measurement of Human Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Angiotensin Converting Enzyme ELISA kit

E01A2159-96 1 plate of 96 wells
EUR 822
Description: A competitive for quantitative measurement of Human Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Angiotensin Converting Enzyme ELISA kit

E06A2159-192T 192 tests
EUR 1524
Description: A competitive for quantitative measurement of Goat Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Angiotensin Converting Enzyme ELISA kit

E06A2159-48 1 plate of 48 wells
EUR 624
Description: A competitive for quantitative measurement of Goat Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Angiotensin Converting Enzyme ELISA kit

E06A2159-96 1 plate of 96 wells
EUR 822
Description: A competitive for quantitative measurement of Goat Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Angiotensin Converting Enzyme ELISA kit

E03A2159-192T 192 tests
EUR 1524
Description: A competitive for quantitative measurement of Mouse Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Angiotensin Converting Enzyme ELISA kit

E03A2159-48 1 plate of 48 wells
EUR 624
Description: A competitive for quantitative measurement of Mouse Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Angiotensin Converting Enzyme ELISA kit

E03A2159-96 1 plate of 96 wells
EUR 822
Description: A competitive for quantitative measurement of Mouse Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Angiotensin Converting Enzyme ELISA kit

E08A2159-192T 192 tests
EUR 1524
Description: A competitive for quantitative measurement of Canine Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Angiotensin Converting Enzyme ELISA kit

E08A2159-48 1 plate of 48 wells
EUR 624
Description: A competitive for quantitative measurement of Canine Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Angiotensin Converting Enzyme ELISA kit

E08A2159-96 1 plate of 96 wells
EUR 822
Description: A competitive for quantitative measurement of Canine Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Angiotensin Converting Enzyme ELISA kit

E02A2159-192T 192 tests
EUR 1524
Description: A competitive for quantitative measurement of Rat Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Angiotensin Converting Enzyme ELISA kit

E02A2159-48 1 plate of 48 wells
EUR 624
Description: A competitive for quantitative measurement of Rat Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Angiotensin Converting Enzyme ELISA kit

E02A2159-96 1 plate of 96 wells
EUR 822
Description: A competitive for quantitative measurement of Rat Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Angiotensin Converting Enzyme ELISA kit

E09A2159-192T 192 tests
EUR 1524
Description: A competitive for quantitative measurement of Monkey Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Angiotensin Converting Enzyme ELISA kit

E09A2159-48 1 plate of 48 wells
EUR 624
Description: A competitive for quantitative measurement of Monkey Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Angiotensin Converting Enzyme ELISA kit

E09A2159-96 1 plate of 96 wells
EUR 822
Description: A competitive for quantitative measurement of Monkey Angiotensin Converting Enzyme in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Anti-Angiotensin Converting Enzyme 1 antibody

STJ99092 200 µl
EUR 236.4
Description: Mouse monoclonal to Angiotensin Converting Enzyme 1.

Recombinant Angiotensin I Converting Enzyme (ACE)

4-RPA004Hu01
  • EUR 532.87
  • EUR 266.40
  • EUR 1668.29
  • EUR 636.10
  • EUR 1152.19
  • EUR 432.00
  • EUR 3990.72
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Angiotensin I Converting Enzyme expressed in: E.coli

Recombinant Angiotensin I Converting Enzyme (ACE)

4-RPA004Hu02
  • EUR 532.87
  • EUR 266.40
  • EUR 1668.29
  • EUR 636.10
  • EUR 1152.19
  • EUR 432.00
  • EUR 3990.72
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Angiotensin I Converting Enzyme expressed in: E.coli

Recombinant Angiotensin I Converting Enzyme (ACE)

4-RPA004Mu01
  • EUR 571.58
  • EUR 276.00
  • EUR 1813.44
  • EUR 684.48
  • EUR 1248.96
  • EUR 458.40
  • EUR 4353.60
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Angiotensin I Converting Enzyme expressed in: E.coli

Recombinant Angiotensin I Converting Enzyme (ACE)

4-RPA004Mu02
  • EUR 571.58
  • EUR 276.00
  • EUR 1813.44
  • EUR 684.48
  • EUR 1248.96
  • EUR 458.40
  • EUR 4353.60
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Angiotensin I Converting Enzyme expressed in: E.coli

Recombinant Angiotensin I Converting Enzyme (ACE)

4-RPA004Mu03
  • EUR 571.58
  • EUR 276.00
  • EUR 1813.44
  • EUR 684.48
  • EUR 1248.96
  • EUR 458.40
  • EUR 4353.60
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Angiotensin I Converting Enzyme expressed in: E.coli

Recombinant Angiotensin I Converting Enzyme (ACE)

4-RPA004Po01
  • EUR 601.69
  • EUR 284.40
  • EUR 1926.34
  • EUR 722.11
  • EUR 1324.22
  • EUR 477.60
  • EUR 4635.84
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Pig Angiotensin I Converting Enzyme expressed in: E.coli

Recombinant Angiotensin I Converting Enzyme (ACE)

4-RPA004Rb01
  • EUR 636.10
  • EUR 294.00
  • EUR 2055.36
  • EUR 765.12
  • EUR 1410.24
  • EUR 501.60
  • EUR 4958.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rabbit Angiotensin I Converting Enzyme expressed in: E.coli

Anti-Angiotensin Converting Enzyme 1 (6A4)

YF-MA12650 100 ug
EUR 435.6
Description: Mouse monoclonal to Angiotensin Converting Enzyme 1

Anti-Angiotensin Converting Enzyme 1 (4B10)

YF-MA12651 100 ug
EUR 435.6
Description: Mouse monoclonal to Angiotensin Converting Enzyme 1

Angiotensin-Converting Enzyme 2 Antibody (ACE2)

F49434-0.08ML 0.08 ml
EUR 165

Angiotensin-Converting Enzyme 2 Antibody (ACE2)

F52229-0.08ML 0.08 ml
EUR 165

ACE Antibody / Angiotensin I Converting Enzyme

V8490-100UG 100 ug
EUR 499
Description: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

ACE Antibody / Angiotensin I Converting Enzyme

V8490-20UG 20 ug
EUR 219
Description: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

ACE Antibody / Angiotensin I Converting Enzyme

V8490SAF-100UG 100 ug
EUR 499
Description: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

ACE Antibody / Angiotensin I Converting Enzyme

V8534-100UG 100 ug
EUR 499
Description: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

ACE Antibody / Angiotensin I Converting Enzyme

V8534-20UG 20 ug
EUR 219
Description: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

ACE Antibody / Angiotensin I Converting Enzyme

V8534SAF-100UG 100 ug
EUR 499
Description: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

ACE Antibody / Angiotensin I Converting Enzyme

V8535-100UG 100 ug
EUR 499
Description: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

ACE Antibody / Angiotensin I Converting Enzyme

V8535-20UG 20 ug
EUR 219
Description: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

ACE Antibody / Angiotensin I Converting Enzyme

V8535SAF-100UG 100 ug
EUR 499
Description: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.